IE45460L - Propanediol derivative. - Google Patents

Propanediol derivative.

Info

Publication number
IE45460L
IE45460L IE771643A IE164377A IE45460L IE 45460 L IE45460 L IE 45460L IE 771643 A IE771643 A IE 771643A IE 164377 A IE164377 A IE 164377A IE 45460 L IE45460 L IE 45460L
Authority
IE
Ireland
Prior art keywords
compound
ch3o2s
formula
stands
denotes
Prior art date
Application number
IE771643A
Other versions
IE45460B1 (en
Original Assignee
Zambon Chimica
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Zambon Chimica filed Critical Zambon Chimica
Publication of IE45460L publication Critical patent/IE45460L/en
Publication of IE45460B1 publication Critical patent/IE45460B1/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C233/00—Carboxylic acid amides
    • C07C233/01—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
    • C07C233/16—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by singly-bound oxygen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents

Abstract

The compounds of the annexed formula <IMAGE> in which R stands for CH3S- or CH3O2S- and R1 stands for hydrogen or, if R denotes CH3O2S-, for an acyl radical of an aliphatic carboxylic acid having 15-17 C atoms or aminoacetic acid, are prepared by reaction of a compound of the annexed formula <IMAGE> with free trifluoroacetic acid or a functional derivative thereof. The corresponding esters, if R stands for CH3O2S-, are obtained by subsequent esterification to give the corresponding compound in which R1 is an acyl radical. The compound of the formula Ia in which R denotes CH3O2S and R1 denotes hydrogen is also prepared by oxidation of the corresponding methylmercapto compound using a peroxide compound. The esters of aminoacetic acid of the formula Ia can be converted into the corresponding therapeutically utilisable acid addition salts. The compounds obtained show a broad antibiotic spectrum of action and are highly suitable for use in human medicine. [GB1534387A]
IE1643/77A 1976-08-05 1977-08-05 D-threo-1-phenyl-2-trifluoroacetmido-1-3-propanediol derivatives IE45460B1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT26042/76A IT1065143B (en) 1976-08-05 1976-08-05 D-TREO-1-FENYL-2-TRIFLUOROACETAMIDO-1,3-PROPANDIOL DERIVATIVES AND PROCESSES FOR THEIR PREPARATION

Publications (2)

Publication Number Publication Date
IE45460L true IE45460L (en) 1978-02-05
IE45460B1 IE45460B1 (en) 1982-08-25

Family

ID=11218484

Family Applications (1)

Application Number Title Priority Date Filing Date
IE1643/77A IE45460B1 (en) 1976-08-05 1977-08-05 D-threo-1-phenyl-2-trifluoroacetmido-1-3-propanediol derivatives

Country Status (16)

Country Link
JP (1) JPS5321135A (en)
AT (1) AT351018B (en)
AU (1) AU509278B2 (en)
BE (1) BE857543A (en)
CA (1) CA1087207A (en)
CH (1) CH609338A5 (en)
DE (1) DE2735431A1 (en)
ES (1) ES461093A1 (en)
FR (1) FR2360560A1 (en)
GB (1) GB1534387A (en)
HU (1) HU173169B (en)
IE (1) IE45460B1 (en)
IT (1) IT1065143B (en)
NL (1) NL7708695A (en)
PT (1) PT66889B (en)
YU (1) YU40678B (en)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5977276A (en) * 1982-10-27 1984-05-02 松下冷機株式会社 Ice machine
EP0678506A3 (en) 1983-06-02 1996-07-24 Zambon Spa Intermediates for the preparation of 1-(phenyl)-1-hydroxy-2-amino-3-fluoro propane derivatives.
IT1317836B1 (en) * 2000-02-16 2003-07-15 Zambon Spa USE OF TIAMFENICOLO FOR THE PREPARATION OF PHARMACEUTICAL COMPOSITIONS USEFUL FOR THE TREATMENT OF STAPHYLOCOCCI INFECTIONS

Also Published As

Publication number Publication date
DE2735431A1 (en) 1978-02-09
IT1065143B (en) 1985-02-25
IE45460B1 (en) 1982-08-25
HU173169B (en) 1979-03-28
PT66889B (en) 1979-01-25
ES461093A1 (en) 1978-06-16
PT66889A (en) 1977-09-01
JPS5321135A (en) 1978-02-27
AU2765577A (en) 1979-02-08
FR2360560A1 (en) 1978-03-03
AT351018B (en) 1979-07-10
ATA577177A (en) 1978-12-15
GB1534387A (en) 1978-12-06
NL7708695A (en) 1978-02-07
FR2360560B1 (en) 1981-02-06
BE857543A (en) 1977-12-01
YU177977A (en) 1982-10-31
CA1087207A (en) 1980-10-07
CH609338A5 (en) 1979-02-28
YU40678B (en) 1986-04-30
AU509278B2 (en) 1980-05-01

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