IE44591L - Gamma globulin injections. - Google Patents

Gamma globulin injections.

Info

Publication number
IE44591L
IE44591L IE770186A IE18677A IE44591L IE 44591 L IE44591 L IE 44591L IE 770186 A IE770186 A IE 770186A IE 18677 A IE18677 A IE 18677A IE 44591 L IE44591 L IE 44591L
Authority
IE
Ireland
Prior art keywords
tolerated
fractions
gamma
globulin
sheet silicates
Prior art date
Application number
IE770186A
Other versions
IE44591B1 (en
Original Assignee
Armour Pharma
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Armour Pharma filed Critical Armour Pharma
Publication of IE44591L publication Critical patent/IE44591L/en
Publication of IE44591B1 publication Critical patent/IE44591B1/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/06Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies from serum

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicinal Preparation (AREA)
  • Peptides Or Proteins (AREA)
  • Silicates, Zeolites, And Molecular Sieves (AREA)

Abstract

A precipitate, which consists of fractions which are tolerated and those which are not tolerated by the body, of gamma-globulins precipitated from blood and blood products is chemically fractionated. The entire precipitate is for this purpose taken up or dissolved in an aqueous solution which contains macromolecular substances which are capable of uniting with the fractions which are not tolerated. The resulting aqueous solution containing gamma-globulin is then additionally mixed with a suspension of micaceous sheet silicates which have cation-exchange capacity. After a reaction time sufficient for the globulin fractions which are not tolerated to bind, by cation exchange, in the sheets of the sheet silicate has elapsed, a precipitating medium is added in order to remove the gamma-globulin fraction which separates out, together with the sheet silicates. Examples of suitable sheet silicates are bentonite, batavite and vermiculite, and an example of a suitable precipitating medium is polyethylene glycol. [GB1577031A]
IE186/77A 1976-02-07 1977-01-28 Improved process of increasing the intravenous compatibility of gamma globulins IE44591B1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE2604759A DE2604759C2 (en) 1976-02-07 1976-02-07 Method of Obtaining IV Compatible Gamma Globulins

Publications (2)

Publication Number Publication Date
IE44591L true IE44591L (en) 1977-08-07
IE44591B1 IE44591B1 (en) 1982-01-27

Family

ID=5969262

Family Applications (1)

Application Number Title Priority Date Filing Date
IE186/77A IE44591B1 (en) 1976-02-07 1977-01-28 Improved process of increasing the intravenous compatibility of gamma globulins

Country Status (22)

Country Link
JP (1) JPS52117414A (en)
AT (1) AT351672B (en)
AU (1) AU508852B2 (en)
BE (1) BE851151R (en)
CA (1) CA1087524A (en)
CH (1) CH629669A5 (en)
DD (1) DD132758A6 (en)
DE (1) DE2604759C2 (en)
DK (1) DK151609C (en)
ES (1) ES455708A2 (en)
FI (1) FI62624C (en)
FR (1) FR2340738A2 (en)
GB (1) GB1577031A (en)
HU (1) HU177708B (en)
IE (1) IE44591B1 (en)
IN (1) IN144987B (en)
MX (1) MX5356E (en)
NL (1) NL7700975A (en)
PL (1) PL104234B3 (en)
SE (1) SE442707B (en)
YU (1) YU30577A (en)
ZA (1) ZA77684B (en)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2837168A1 (en) * 1978-08-25 1980-03-06 Blutspendedienst Dt Rote Kreuz METHOD FOR PRODUCING AN IMMUNAL GLOBULIN SOLUTION SUITABLE FOR INTRAVENOUS APPLICATION
JPS60222773A (en) * 1984-04-19 1985-11-07 Sekisui Chem Co Ltd Manufacture of latex reagent
EP0168506B2 (en) * 1984-07-07 1998-01-07 Armour Pharma GmbH Process for preparing gamma globulin suitable for intravenous administration
DE3440444A1 (en) * 1984-11-06 1986-05-07 Dechema Deutsche Gesellschaft für chemisches Apparatewesen e.V., 6000 Frankfurt METHOD FOR THE PRODUCTION OF COARSE GRAINED LAYERED SILICATES AND THE USE THEREOF AS ADSORBENTS FOR PROTEINS
UA64742C2 (en) * 1997-12-24 2004-03-15 Альфа Терапевтик Корпорейшн Process for producing intravenously-administrable gamma globulin solution and product manufactured by this process
CA2941232C (en) 2014-03-11 2020-08-25 Green Cross Holdings Corporation Method for purifying immunoglobulin
CN106459140B (en) 2014-03-11 2019-12-10 株式会社绿十字控股 Method for purifying immunoglobulins
KR101657690B1 (en) 2015-06-05 2016-09-19 주식회사 녹십자홀딩스 Methods for Preparing Hepatitis B immune globulin derived from plasma

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3449316A (en) * 1967-03-03 1969-06-10 American Cyanamid Co Process for the purification of gamma globulin employing bentonite
DE2500076C3 (en) * 1975-01-02 1982-11-18 SCHURA Blutderivate GmbH & Co KG, 4150 Krefeld Process for the production of intravenously tolerated gamma globulins

Also Published As

Publication number Publication date
DE2604759A1 (en) 1977-09-29
DK47277A (en) 1977-08-07
AU2190277A (en) 1978-08-10
SE442707B (en) 1986-01-27
FI62624B (en) 1982-10-29
HU177708B (en) 1981-12-28
PL104234B3 (en) 1979-08-31
ZA77684B (en) 1977-12-28
ES455708A2 (en) 1978-01-16
FI62624C (en) 1983-02-10
SE7700960L (en) 1977-08-08
FR2340738B2 (en) 1981-07-31
IE44591B1 (en) 1982-01-27
BE851151R (en) 1977-08-04
NL7700975A (en) 1977-08-09
DK151609B (en) 1987-12-21
CH629669A5 (en) 1982-05-14
DK151609C (en) 1988-06-20
AT351672B (en) 1979-08-10
GB1577031A (en) 1980-10-15
DE2604759C2 (en) 1983-06-01
FR2340738A2 (en) 1977-09-09
AU508852B2 (en) 1980-04-03
JPS52117414A (en) 1977-10-01
FI770290A (en) 1977-08-08
YU30577A (en) 1984-04-30
JPS6231695B2 (en) 1987-07-09
CA1087524A (en) 1980-10-14
IN144987B (en) 1978-08-05
DD132758A6 (en) 1978-11-01
MX5356E (en) 1983-06-29
ATA74177A (en) 1979-01-15

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