ES455708A2 - Process of increasing the intravenous compatibility of gamma globulins - Google Patents
Process of increasing the intravenous compatibility of gamma globulinsInfo
- Publication number
- ES455708A2 ES455708A2 ES455708A ES455708A ES455708A2 ES 455708 A2 ES455708 A2 ES 455708A2 ES 455708 A ES455708 A ES 455708A ES 455708 A ES455708 A ES 455708A ES 455708 A2 ES455708 A2 ES 455708A2
- Authority
- ES
- Spain
- Prior art keywords
- tolerated
- gamma
- fractions
- globulin
- sheet silicates
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/06—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies from serum
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Life Sciences & Earth Sciences (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Immunology (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Medicinal Preparation (AREA)
- Peptides Or Proteins (AREA)
- Silicates, Zeolites, And Molecular Sieves (AREA)
Abstract
A precipitate, which consists of fractions which are tolerated and those which are not tolerated by the body, of gamma-globulins precipitated from blood and blood products is chemically fractionated. The entire precipitate is for this purpose taken up or dissolved in an aqueous solution which contains macromolecular substances which are capable of uniting with the fractions which are not tolerated. The resulting aqueous solution containing gamma-globulin is then additionally mixed with a suspension of micaceous sheet silicates which have cation-exchange capacity. After a reaction time sufficient for the globulin fractions which are not tolerated to bind, by cation exchange, in the sheets of the sheet silicate has elapsed, a precipitating medium is added in order to remove the gamma-globulin fraction which separates out, together with the sheet silicates. Examples of suitable sheet silicates are bentonite, batavite and vermiculite, and an example of a suitable precipitating medium is polyethylene glycol.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE2604759A DE2604759C2 (en) | 1976-02-07 | 1976-02-07 | Method of Obtaining IV Compatible Gamma Globulins |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES455708A2 true ES455708A2 (en) | 1978-01-16 |
Family
ID=5969262
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES455708A Expired ES455708A2 (en) | 1976-02-07 | 1977-02-07 | Process of increasing the intravenous compatibility of gamma globulins |
Country Status (22)
| Country | Link |
|---|---|
| JP (1) | JPS52117414A (en) |
| AT (1) | AT351672B (en) |
| AU (1) | AU508852B2 (en) |
| BE (1) | BE851151R (en) |
| CA (1) | CA1087524A (en) |
| CH (1) | CH629669A5 (en) |
| DD (1) | DD132758A6 (en) |
| DE (1) | DE2604759C2 (en) |
| DK (1) | DK151609C (en) |
| ES (1) | ES455708A2 (en) |
| FI (1) | FI62624C (en) |
| FR (1) | FR2340738A2 (en) |
| GB (1) | GB1577031A (en) |
| HU (1) | HU177708B (en) |
| IE (1) | IE44591B1 (en) |
| IN (1) | IN144987B (en) |
| MX (1) | MX5356E (en) |
| NL (1) | NL7700975A (en) |
| PL (1) | PL104234B3 (en) |
| SE (1) | SE442707B (en) |
| YU (1) | YU30577A (en) |
| ZA (1) | ZA77684B (en) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE2837168A1 (en) * | 1978-08-25 | 1980-03-06 | Blutspendedienst Dt Rote Kreuz | METHOD FOR PRODUCING AN IMMUNAL GLOBULIN SOLUTION SUITABLE FOR INTRAVENOUS APPLICATION |
| JPS60222773A (en) * | 1984-04-19 | 1985-11-07 | Sekisui Chem Co Ltd | Manufacture of latex reagent |
| EP0168506B2 (en) * | 1984-07-07 | 1998-01-07 | Armour Pharma GmbH | Process for preparing gamma globulin suitable for intravenous administration |
| DE3440444A1 (en) * | 1984-11-06 | 1986-05-07 | Dechema Deutsche Gesellschaft für chemisches Apparatewesen e.V., 6000 Frankfurt | METHOD FOR THE PRODUCTION OF COARSE GRAINED LAYERED SILICATES AND THE USE THEREOF AS ADSORBENTS FOR PROTEINS |
| UA64742C2 (en) * | 1997-12-24 | 2004-03-15 | Альфа Терапевтик Корпорейшн | Process for producing intravenously-administrable gamma globulin solution and product manufactured by this process |
| EP3118210B1 (en) | 2014-03-11 | 2019-11-13 | Green Cross Holdings Corporation | Method for purifying immunoglobulin |
| EP3118209B1 (en) | 2014-03-11 | 2020-02-19 | Green Cross Holdings Corporation | Method for purifying immunoglobulin |
| KR101657690B1 (en) | 2015-06-05 | 2016-09-19 | 주식회사 녹십자홀딩스 | Methods for Preparing Hepatitis B immune globulin derived from plasma |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3449316A (en) * | 1967-03-03 | 1969-06-10 | American Cyanamid Co | Process for the purification of gamma globulin employing bentonite |
| DE2500076C3 (en) * | 1975-01-02 | 1982-11-18 | SCHURA Blutderivate GmbH & Co KG, 4150 Krefeld | Process for the production of intravenously tolerated gamma globulins |
-
1976
- 1976-02-07 DE DE2604759A patent/DE2604759C2/en not_active Expired
-
1977
- 1977-01-28 FI FI770290A patent/FI62624C/en not_active IP Right Cessation
- 1977-01-28 IE IE186/77A patent/IE44591B1/en unknown
- 1977-01-31 NL NL7700975A patent/NL7700975A/en not_active Application Discontinuation
- 1977-01-31 SE SE7700960A patent/SE442707B/en not_active IP Right Cessation
- 1977-02-03 AU AU21902/77A patent/AU508852B2/en not_active Expired
- 1977-02-04 DK DK047277A patent/DK151609C/en not_active IP Right Cessation
- 1977-02-04 BE BE6045865A patent/BE851151R/en not_active IP Right Cessation
- 1977-02-04 DD DD7700197241A patent/DD132758A6/en unknown
- 1977-02-04 FR FR7703139A patent/FR2340738A2/en active Granted
- 1977-02-04 HU HU77PA1277A patent/HU177708B/en unknown
- 1977-02-04 PL PL1977195821A patent/PL104234B3/en unknown
- 1977-02-04 YU YU00305/77A patent/YU30577A/en unknown
- 1977-02-04 MX MX775414U patent/MX5356E/en unknown
- 1977-02-04 AT AT74177A patent/AT351672B/en not_active IP Right Cessation
- 1977-02-05 IN IN168/CAL/77A patent/IN144987B/en unknown
- 1977-02-07 GB GB5017/77A patent/GB1577031A/en not_active Expired
- 1977-02-07 ZA ZA770684A patent/ZA77684B/en unknown
- 1977-02-07 ES ES455708A patent/ES455708A2/en not_active Expired
- 1977-02-07 JP JP1172177A patent/JPS52117414A/en active Granted
- 1977-02-07 CA CA271,204A patent/CA1087524A/en not_active Expired
- 1977-02-07 CH CH146277A patent/CH629669A5/en not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| DE2604759A1 (en) | 1977-09-29 |
| MX5356E (en) | 1983-06-29 |
| DK151609C (en) | 1988-06-20 |
| DE2604759C2 (en) | 1983-06-01 |
| DK151609B (en) | 1987-12-21 |
| FR2340738A2 (en) | 1977-09-09 |
| ZA77684B (en) | 1977-12-28 |
| FI62624B (en) | 1982-10-29 |
| SE442707B (en) | 1986-01-27 |
| SE7700960L (en) | 1977-08-08 |
| AU508852B2 (en) | 1980-04-03 |
| HU177708B (en) | 1981-12-28 |
| DD132758A6 (en) | 1978-11-01 |
| FI62624C (en) | 1983-02-10 |
| DK47277A (en) | 1977-08-07 |
| IN144987B (en) | 1978-08-05 |
| AT351672B (en) | 1979-08-10 |
| FR2340738B2 (en) | 1981-07-31 |
| AU2190277A (en) | 1978-08-10 |
| JPS52117414A (en) | 1977-10-01 |
| CA1087524A (en) | 1980-10-14 |
| FI770290A (en) | 1977-08-08 |
| IE44591L (en) | 1977-08-07 |
| PL104234B3 (en) | 1979-08-31 |
| JPS6231695B2 (en) | 1987-07-09 |
| YU30577A (en) | 1984-04-30 |
| IE44591B1 (en) | 1982-01-27 |
| ATA74177A (en) | 1979-01-15 |
| GB1577031A (en) | 1980-10-15 |
| BE851151R (en) | 1977-08-04 |
| CH629669A5 (en) | 1982-05-14 |
| NL7700975A (en) | 1977-08-09 |
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