IE44471L - Stabilized erythrocytes and their use - Google Patents

Stabilized erythrocytes and their use

Info

Publication number
IE44471L
IE44471L IE249476A IE249476A IE44471L IE 44471 L IE44471 L IE 44471L IE 249476 A IE249476 A IE 249476A IE 249476 A IE249476 A IE 249476A IE 44471 L IE44471 L IE 44471L
Authority
IE
Ireland
Prior art keywords
erythrocytes
coated
aldehyde
erythrocyte preparations
chromium
Prior art date
Application number
IE249476A
Other versions
IE44471B1 (en
Original Assignee
Behringwerke Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Behringwerke Ag filed Critical Behringwerke Ag
Publication of IE44471L publication Critical patent/IE44471L/en
Publication of IE44471B1 publication Critical patent/IE44471B1/en

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/554—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals the carrier being a biological cell or cell fragment, e.g. bacteria, yeast cells
    • G01N33/555—Red blood cell
    • G01N33/556—Fixed or stabilised red blood cell
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N1/00—Preservation of bodies of humans or animals, or parts thereof
    • A01N1/02—Preservation of living parts
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N1/00—Preservation of bodies of humans or animals, or parts thereof
    • A01N1/02—Preservation of living parts
    • A01N1/0205—Chemical aspects
    • A01N1/021—Preservation or perfusion media, liquids, solids or gases used in the preservation of cells, tissue, organs or bodily fluids
    • A01N1/0221—Freeze-process protecting agents, i.e. substances protecting cells from effects of the physical process, e.g. cryoprotectants, osmolarity regulators like oncotic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/14—Blood; Artificial blood
    • A61K35/18—Erythrocytes

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Cell Biology (AREA)
  • Hematology (AREA)
  • Immunology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biomedical Technology (AREA)
  • Zoology (AREA)
  • Chemical & Material Sciences (AREA)
  • Molecular Biology (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Environmental Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Dentistry (AREA)
  • Urology & Nephrology (AREA)
  • Mycology (AREA)
  • General Physics & Mathematics (AREA)
  • Public Health (AREA)
  • Developmental Biology & Embryology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Food Science & Technology (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • Veterinary Medicine (AREA)
  • Pathology (AREA)
  • Epidemiology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Virology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)

Abstract

Stable lyophilisable erythrocyte preparations are obtained by treating erythrocytes which are suspended in aqueous isotonic solutions with a lower aliphatic aldehyde and a water-soluble salt of 2- or 3-valent chromium. The treatment with aldehyde and the chromium salts can take place successively in any desired sequence or simultaneously. The treated erythrocytes are washed and, if required, lyophilised. The resulting stabilised erythrocyte preparations can be coated with antigen and antibodies too. The coated erythrocytes can be employed for haemagglutination tests. [GB1563839A]
IE249476A 1975-11-14 1976-11-12 Stable preparation of erythrocytes process for preparing it and its use IE44471B1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19752551208 DE2551208C3 (en) 1975-11-14 1975-11-14 Process for the production of a stable erythrocyte preparation

Publications (2)

Publication Number Publication Date
IE44471L true IE44471L (en) 1977-05-14
IE44471B1 IE44471B1 (en) 1981-12-16

Family

ID=5961771

Family Applications (1)

Application Number Title Priority Date Filing Date
IE249476A IE44471B1 (en) 1975-11-14 1976-11-12 Stable preparation of erythrocytes process for preparing it and its use

Country Status (18)

Country Link
JP (1) JPS5261218A (en)
AR (1) AR213420A1 (en)
AT (1) AT356812B (en)
AU (1) AU511427B2 (en)
BE (1) BE848377A (en)
BR (1) BR7607564A (en)
CH (1) CH626999A5 (en)
DE (1) DE2551208C3 (en)
DK (1) DK146138C (en)
ES (1) ES453136A1 (en)
FR (1) FR2331352A1 (en)
GB (1) GB1563839A (en)
IE (1) IE44471B1 (en)
IT (1) IT1063992B (en)
LU (1) LU76194A1 (en)
MX (1) MX3937E (en)
NL (1) NL189133C (en)
SE (1) SE431800B (en)

Families Citing this family (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2828820A1 (en) * 1977-08-01 1979-02-08 Warner Lambert Co METHOD OF MANUFACTURING STABLE PLATE SUSPENSION AND STABLE PLATE SUSPENSION OBTAINED BY THE METHOD
US4302355A (en) * 1977-08-01 1981-11-24 Warner-Lambert Company Platelet reference control
JPS5917388B2 (en) * 1979-02-22 1984-04-20 富士レビオ株式会社 Absorbent for indirect flocculation reaction
EP0039195B1 (en) * 1980-04-28 1986-06-18 Montefiore Hospital and Medical Center Antibody detection process
GB2138132B (en) * 1983-04-12 1987-02-18 Robin Royston Amos Coombs Storage-stable antibody-linked erythrocytes
JPS6161055A (en) * 1984-08-31 1986-03-28 Shionogi & Co Ltd Preservative liquid of fixed red blood cells of aves for virus hemagglutination test
DE3501496A1 (en) * 1985-01-18 1986-07-24 Behringwerke Ag, 3550 Marburg METHOD FOR DETERMINING THE ACTIVITY OF THE COMPLEMENT SYSTEM OF THE BLOOD
FR2617185B1 (en) * 1987-06-25 1990-03-09 Fondation Nale Transfusion San METHOD FOR STABILIZING CELL MEMBRANES AND ITS APPLICATION TO THE PRESERVATION OF CELLS IN A FORM PROTECTING THE ESSENTIALS OF THEIR SURFACE ANTIGENS
US5079173A (en) * 1987-08-19 1992-01-07 Shionogi & Co., Ltd. Methods, hybridomas, monoclonal antibodies and sensitized cells for measuring hbs antigen
JPH01107154A (en) * 1987-10-20 1989-04-25 Seitetsu Kagaku Co Ltd Processed red blood-corpuscle and its manufacturing method
IL90188A0 (en) * 1988-05-18 1989-12-15 Cryopharm Corp Process and medium for the lyophilization of erythrocytes
US5045446A (en) * 1988-08-26 1991-09-03 Cryopharm Corporation Lyophilization of cells
EP0356258A3 (en) * 1988-08-26 1990-06-06 Cryopharm Corporation Processes for the lyophilization of red blood cells, together with media for lyophilization
US5059518A (en) * 1988-10-20 1991-10-22 Coulter Corporation Stabilized lyophilized mammalian cells and method of making same
BR9106374A (en) * 1990-04-24 1993-03-30 Univ Newcastle Res Ass ORAL VACCINE AND THE PROCESS OF EXTRACTING AN IMMUNORESPONSTA IN A MAMMAL
US5882649A (en) * 1990-04-24 1999-03-16 Flustat Pty. Ltd. Oral vaccine comprising antigen surface-associated with red blood cells
BR9407003A (en) * 1993-07-05 1996-03-26 North Gen Hospital Nhs Trust Preparation and stabilization of cells
EP0721104A2 (en) * 1993-07-05 1996-07-10 Northern General Hospital N.H.S. Trust Preparation and stabilisation of cells
US5858699A (en) * 1994-04-05 1999-01-12 Northern General Hospital Nhs Trust Method to stabilize cell suspensions using aged heavy metal solution and paraformaldehyde
GB2313288B (en) * 1996-05-24 2000-07-12 North Gen Hospital Nhs Trust Specimen collection fluid
CN100376669C (en) 2005-02-25 2008-03-26 深圳迈瑞生物医疗电子股份有限公司 Treatment method for biological erythrocyte volume long time stabilization
JP7110360B2 (en) 2017-10-09 2022-08-01 テルモ ビーシーティー バイオテクノロジーズ，エルエルシー Freeze-drying method
JP7379361B2 (en) * 2018-03-27 2023-11-14 イグザクト サイエンシーズ コーポレイション Methods for stabilizing hemoglobin and reagents for the same
CN113614477B (en) 2019-03-14 2023-04-28 泰尔茂比司特生物技术有限公司 Freeze-drying loading tray assembly and system
FR3121577B1 (en) 2021-04-12 2024-03-08 Elitech Microbio Stabilizing composition, process using said composition for the manufacture of control products for analyzes of biological samples in mammals, and control products resulting from the implementation of said process
CN115399314B (en) * 2022-11-01 2023-05-19 天津德祥生物技术股份有限公司 Human ABO blood type inverse typing red blood cell capable of being freeze-dried and stored and storage method

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR1521350A (en) * 1965-09-10 1968-04-19 Princeton Lab Mononucleosis detection
DE2025718C3 (en) * 1967-11-13 1979-06-13 Abbott Laboratories, Chicago, Ill. (V.St.A.) Method for stabilizing lyophilized erythrocytes
GB1244344A (en) * 1967-11-13 1971-08-25 Abbott Lab Hemagglutination testing procedure employing stabilized and potentiated erythrocytes and a method for their preparation
FR2233024A1 (en) * 1973-06-15 1975-01-10 Greyward Lab Interconti Treponema haemagglutination test - using tanned avian erythrocytes as carrier for ireponema antigen

Also Published As

Publication number Publication date
MX3937E (en) 1981-10-02
SE431800B (en) 1984-02-27
LU76194A1 (en) 1977-06-06
GB1563839A (en) 1980-04-02
IE44471B1 (en) 1981-12-16
AT356812B (en) 1980-05-27
AU1958876A (en) 1978-05-18
NL7612439A (en) 1977-05-17
DK146138C (en) 1983-11-28
ES453136A1 (en) 1978-01-16
NL189133C (en) 1993-01-18
BR7607564A (en) 1977-09-27
FR2331352B1 (en) 1982-07-09
AR213420A1 (en) 1979-01-31
DK146138B (en) 1983-07-04
ATA843476A (en) 1979-10-15
CH626999A5 (en) 1981-12-15
JPS5261218A (en) 1977-05-20
JPS616941B2 (en) 1986-03-03
AU511427B2 (en) 1980-08-21
DE2551208A1 (en) 1977-05-26
DE2551208C3 (en) 1981-05-27
BE848377A (en) 1977-05-16
IT1063992B (en) 1985-02-18
DK510976A (en) 1977-05-15
FR2331352A1 (en) 1977-06-10
NL189133B (en) 1992-08-17
DE2551208B2 (en) 1980-09-11
SE7612622L (en) 1977-05-15

Similar Documents

Publication Publication Date Title
IE44471L (en) Stabilized erythrocytes and their use
NL174250B (en) PROCESS FOR PREPARING A FUNGICIDE PREPARATION BY INCLUDING D-DERIVATIVES OF N-BENZYL N'-PHENYLUREA OR THIOUREA AS THE ACTIVE SUBSTANCE IN A CARRIER, AND THE DERIVATIVES OF N-BENZYLEA-N'-PHENYLURA SUITABLE THEREFOR.
DE3685625D1 (en) ANTIBODY COMPLEXES OF HAPTEN-MODIFIED DIAGNOSTIC OR THERAPEUTIC AGENTS.
NL7711026A (en) PROCESS FOR PREPARING A PREPARATION FOR TREATING ALLERGENS AND PROCESS FOR PREPARING A MULTIVALENT ANTIGENE PROTEIN COMPLEX, STOPPING ALLERGIC REACTIONS
SE8300320D0 (en) MONOCLONAL ANTIBODY FORMULATION FOR DIAGNOSTIC USE
GB1528071A (en) Radioimmunoassay
NL169733C (en) METHOD FOR PREPARING OR MANUFACTURING A PHARMACEUTICAL PREPARATION WITH BETA-ADRENOLYTIC AND BLOOD PRESSURE-REDUCING PROCESS AND METHOD FOR PREPARING THE USE THEREFROMENOUS-1-ARYLOXY-2-HYDROXY-IN-AMINOPROPRODE-PROPINE ACCEPTABLE SALTS THEREOF.
NO874453D0 (en) PROCEDURE FOR DETERMINING ANTI-HIV, ITS MEDICINE AND ITS USE IN THE PROCEDURE.
SE7704359L (en) PROCEDURE FOR ENRICHMENT OF A PLACENTAS-SPECIFIC GLYCOPROTEIN
NL175297B (en) PROCESS FOR PREPARING AND / OR MANUFACTURING A PHARMACEUTICAL PREPARATION CONTAINING ONE OR A NUMBER OF MORFANTHRIDINE DERIVATIVES SUBSTITUTED IN THE 6-PLACE AND / OR THE ACID ADDITION SALTS OF ITS PROPERTIES.
NL7609451A (en) NEW TRIFLUORMETHYLPHENOXY-PHENYLUREA, METHOD FOR PREPARATION AND METHOD FOR PREPARING HERBICIDE PREPARATIONS.
ES8800757A1 (en) Reagent for the determination by haemagglutination of antibodies against bacterial toxins, method for its preparation and its use.
BR7700662A (en) NEW DYES OF THE CHROME COMPLEX, ITS PREPARATION AND APPLICATION
NL7610094A (en) N- (1.2.4-TRIAZINE 5-ON 4-YL) GLYCINE DERIVATIVES, A METHOD OF PREPARING THEM AND USE AS A HERBICIDE.
GB1423992A (en) Photosensitive material of biological origin
GB1334884A (en) Aminoalcohols and their conversion to aminoketones
BR7703199A (en) SOLUBLE TRISAZOUS DYES, THEIR PREPARATION AND APPLICATION
Rodman et al. A comparison of laboratory methods for the control of anticoagulant therapy with prothrombinopenic agents. II. Problems encountered in the laboratory control of anticoagulant therapy with one-stage determination of prothrombin complex activity
SU641320A1 (en) Method of non-destructive checking of article strength
SE7614579L (en) PROTHETIC HEART VALVE WITH IMPROVED SUTURING
GB1356503A (en) Diagnostic method and means therefor
ATE80306T1 (en) MEANS FOR IMPROVING ABSORPTION OF PROTEINS.
Cimino et al. Effect of Zn, Ga and Ge Ions on the Structural and Magnetic Properties of Ni Ions Supported on Alumina
JPS51144724A (en) A process for preparing alpha-fetoprotein standard serum which is usable for a long time
NL7604545A (en) POLYETHERURETHANES, METHOD FOR PREPARING THEM AND THEIR USE AS ANTISTATICALLY ACTIVE ADDITIONS IN POLYAMIDEMASSES.

Legal Events

Date Code Title Description
MM4A Patent lapsed