IE43978L - Pharmaceutical composition; 1,3-dialkyl-7-oxoalkylxanthines - Google Patents
Pharmaceutical composition; 1,3-dialkyl-7-oxoalkylxanthinesInfo
- Publication number
- IE43978L IE43978L IE760183A IE18376A IE43978L IE 43978 L IE43978 L IE 43978L IE 760183 A IE760183 A IE 760183A IE 18376 A IE18376 A IE 18376A IE 43978 L IE43978 L IE 43978L
- Authority
- IE
- Ireland
- Prior art keywords
- formula
- reaction
- compound
- radical
- oxoalkylxanthines
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D473/00—Heterocyclic compounds containing purine ring systems
- C07D473/02—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6
- C07D473/04—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two oxygen atoms
- C07D473/06—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two oxygen atoms with radicals containing only hydrogen and carbon atoms, attached in position 1 or 3
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
By reaction of a compound of the formula II <IMAGE> or a salt thereof with an agent introducing a radical of the formula -A-CO-CH3 (III> in particular by reaction of a compound of the formula II with a ketone of the formula CH2=CR-CO-CH3 (V> wherein in the above formulae the radicals R1, A and R have the meanings given in Patent Claims 1 and 4, the corresponding 7-substituted xanthine derivatives are obtained. During the reaction, the carbonyl group of the radical of the formula III or of the compound of the formula V is optionally intermediately protected. The novel compounds are useful medicaments for the treatment of disorders of the cardiovascular system, since they improve the circulation of the skeletal musculature and/or decrease or prevent arrhythmias.
[GB1496316A]
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE19752507555 DE2507555A1 (en) | 1975-02-21 | 1975-02-21 | 7- (OXOALKYL) -1,3-DIALKYLXANTHINE, THE METHOD OF MANUFACTURING THEREOF AND MEDICINAL PRODUCTS CONTAINING THIS COMPOUND |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| IE43978L true IE43978L (en) | 1976-08-21 |
| IE43978B1 IE43978B1 (en) | 1981-07-15 |
Family
ID=5939491
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IE183/76A IE43978B1 (en) | 1975-02-21 | 1976-01-30 | 1,3-dialkyl-7-oxoalkylaxanthines |
Country Status (18)
| Country | Link |
|---|---|
| JP (1) | JPS51110598A (en) |
| AR (2) | AR208755A1 (en) |
| AT (1) | AT342617B (en) |
| AU (1) | AU506542B2 (en) |
| BE (1) | BE838466A (en) |
| CH (1) | CH621789A5 (en) |
| DE (1) | DE2507555A1 (en) |
| DK (1) | DK72676A (en) |
| ES (1) | ES445301A1 (en) |
| FI (1) | FI760418A (en) |
| FR (1) | FR2301258A1 (en) |
| GB (1) | GB1496316A (en) |
| HU (1) | HU174656B (en) |
| IE (1) | IE43978B1 (en) |
| NL (1) | NL7601622A (en) |
| SE (1) | SE7601455L (en) |
| YU (1) | YU37276A (en) |
| ZA (1) | ZA76568B (en) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0570831A2 (en) * | 1992-05-20 | 1993-11-24 | Hoechst Aktiengesellschaft | Use of Xanthinderivatives for treatment of cerebral nerve dammages after disruption of the blood circulation |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2761863A (en) * | 1956-09-04 | Lower-alkyl | ||
| DE932489C (en) * | 1953-09-11 | 1955-09-01 | Hoffmann La Roche | Process for the production of new xanthine bases and their salts |
| CH325292A (en) * | 1953-10-21 | 1957-10-31 | Geigy Ag J R | Process for the preparation of 7-oxyalkyl-xanthine derivatives |
| DE1233405B (en) * | 1964-09-05 | 1967-02-02 | Albert Ag Chem Werke | Process for the preparation of 7- (oxoalkyl) -1, 3-dimethylxanthines |
| US3422107A (en) * | 1964-09-05 | 1969-01-14 | Albert Ag Chem Werke | Certain oxoalkyldimethylxanthines and a process for the preparation thereof |
| DE2234202A1 (en) * | 1972-07-12 | 1974-01-24 | Albert Ag Chem Werke | Prep. of oxoalkylxanthine - this has e.g. broncholytic and fibrinolytic activity |
| DE2330742C2 (en) * | 1973-06-16 | 1982-07-29 | Hoechst Ag, 6000 Frankfurt | 1- (Oxoalkyl) -3-methyl-7-alkylxanthines, process for their preparation and pharmaceuticals containing them |
| CH608236A5 (en) * | 1974-01-22 | 1978-12-29 | Wuelfing J A Fa |
-
1975
- 1975-02-21 DE DE19752507555 patent/DE2507555A1/en not_active Withdrawn
-
1976
- 1976-01-30 IE IE183/76A patent/IE43978B1/en unknown
- 1976-02-02 ZA ZA568A patent/ZA76568B/en unknown
- 1976-02-09 FR FR7603413A patent/FR2301258A1/en active Granted
- 1976-02-10 AT AT89776A patent/AT342617B/en not_active IP Right Cessation
- 1976-02-10 SE SE7601455A patent/SE7601455L/en unknown
- 1976-02-11 BE BE164248A patent/BE838466A/en not_active IP Right Cessation
- 1976-02-11 GB GB5326/76A patent/GB1496316A/en not_active Expired
- 1976-02-12 HU HU76WU22A patent/HU174656B/en unknown
- 1976-02-13 AR AR262265A patent/AR208755A1/en active
- 1976-02-17 YU YU00372/76A patent/YU37276A/en unknown
- 1976-02-18 ES ES445301A patent/ES445301A1/en not_active Expired
- 1976-02-18 NL NL7601622A patent/NL7601622A/en not_active Application Discontinuation
- 1976-02-19 FI FI760418A patent/FI760418A/fi not_active Application Discontinuation
- 1976-02-20 JP JP51017837A patent/JPS51110598A/ja active Pending
- 1976-02-20 CH CH210676A patent/CH621789A5/en not_active IP Right Cessation
- 1976-02-20 DK DK72676*#A patent/DK72676A/en unknown
- 1976-02-23 AU AU11338/76A patent/AU506542B2/en not_active Expired
- 1976-09-29 AR AR264907A patent/AR210168A1/en active
Also Published As
| Publication number | Publication date |
|---|---|
| YU37276A (en) | 1982-08-31 |
| NL7601622A (en) | 1976-08-24 |
| AR208755A1 (en) | 1977-02-28 |
| AR210168A1 (en) | 1977-06-30 |
| BE838466A (en) | 1976-08-11 |
| FR2301258A1 (en) | 1976-09-17 |
| JPS51110598A (en) | 1976-09-30 |
| AU1133876A (en) | 1977-09-01 |
| ATA89776A (en) | 1977-08-15 |
| HU174656B (en) | 1980-02-28 |
| SE7601455L (en) | 1976-08-22 |
| DE2507555A1 (en) | 1976-09-02 |
| AU506542B2 (en) | 1980-01-10 |
| AT342617B (en) | 1978-04-10 |
| DK72676A (en) | 1976-08-22 |
| FR2301258B1 (en) | 1978-11-17 |
| GB1496316A (en) | 1977-12-30 |
| FI760418A (en) | 1976-08-22 |
| CH621789A5 (en) | 1981-02-27 |
| ZA76568B (en) | 1977-01-26 |
| ES445301A1 (en) | 1977-06-01 |
| IE43978B1 (en) | 1981-07-15 |
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