IE43978L - Pharmaceutical composition; 1,3-dialkyl-7-oxoalkylxanthines - Google Patents

Pharmaceutical composition; 1,3-dialkyl-7-oxoalkylxanthines

Info

Publication number
IE43978L
IE43978L IE760183A IE18376A IE43978L IE 43978 L IE43978 L IE 43978L IE 760183 A IE760183 A IE 760183A IE 18376 A IE18376 A IE 18376A IE 43978 L IE43978 L IE 43978L
Authority
IE
Ireland
Prior art keywords
formula
reaction
compound
radical
oxoalkylxanthines
Prior art date
Application number
IE760183A
Other versions
IE43978B1 (en
Original Assignee
Wuelfing Johann A
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Wuelfing Johann A filed Critical Wuelfing Johann A
Publication of IE43978L publication Critical patent/IE43978L/en
Publication of IE43978B1 publication Critical patent/IE43978B1/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D473/00—Heterocyclic compounds containing purine ring systems
    • C07D473/02—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6
    • C07D473/04—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two oxygen atoms
    • C07D473/06—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two oxygen atoms with radicals containing only hydrogen and carbon atoms, attached in position 1 or 3

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

By reaction of a compound of the formula II <IMAGE> or a salt thereof with an agent introducing a radical of the formula -A-CO-CH3 (III> in particular by reaction of a compound of the formula II with a ketone of the formula CH2=CR-CO-CH3 (V> wherein in the above formulae the radicals R1, A and R have the meanings given in Patent Claims 1 and 4, the corresponding 7-substituted xanthine derivatives are obtained. During the reaction, the carbonyl group of the radical of the formula III or of the compound of the formula V is optionally intermediately protected. The novel compounds are useful medicaments for the treatment of disorders of the cardiovascular system, since they improve the circulation of the skeletal musculature and/or decrease or prevent arrhythmias. [GB1496316A]
IE183/76A 1975-02-21 1976-01-30 1,3-dialkyl-7-oxoalkylaxanthines IE43978B1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19752507555 DE2507555A1 (en) 1975-02-21 1975-02-21 7- (OXOALKYL) -1,3-DIALKYLXANTHINE, THE METHOD OF MANUFACTURING THEREOF AND MEDICINAL PRODUCTS CONTAINING THIS COMPOUND

Publications (2)

Publication Number Publication Date
IE43978L true IE43978L (en) 1976-08-21
IE43978B1 IE43978B1 (en) 1981-07-15

Family

ID=5939491

Family Applications (1)

Application Number Title Priority Date Filing Date
IE183/76A IE43978B1 (en) 1975-02-21 1976-01-30 1,3-dialkyl-7-oxoalkylaxanthines

Country Status (18)

Country Link
JP (1) JPS51110598A (en)
AR (2) AR208755A1 (en)
AT (1) AT342617B (en)
AU (1) AU506542B2 (en)
BE (1) BE838466A (en)
CH (1) CH621789A5 (en)
DE (1) DE2507555A1 (en)
DK (1) DK72676A (en)
ES (1) ES445301A1 (en)
FI (1) FI760418A (en)
FR (1) FR2301258A1 (en)
GB (1) GB1496316A (en)
HU (1) HU174656B (en)
IE (1) IE43978B1 (en)
NL (1) NL7601622A (en)
SE (1) SE7601455L (en)
YU (1) YU37276A (en)
ZA (1) ZA76568B (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0570831A2 (en) * 1992-05-20 1993-11-24 Hoechst Aktiengesellschaft Use of Xanthinderivatives for treatment of cerebral nerve dammages after disruption of the blood circulation

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2761863A (en) * 1956-09-04 Lower-alkyl
DE932489C (en) * 1953-09-11 1955-09-01 Hoffmann La Roche Process for the production of new xanthine bases and their salts
CH325292A (en) * 1953-10-21 1957-10-31 Geigy Ag J R Process for the preparation of 7-oxyalkyl-xanthine derivatives
DE1233405B (en) * 1964-09-05 1967-02-02 Albert Ag Chem Werke Process for the preparation of 7- (oxoalkyl) -1, 3-dimethylxanthines
US3422107A (en) * 1964-09-05 1969-01-14 Albert Ag Chem Werke Certain oxoalkyldimethylxanthines and a process for the preparation thereof
DE2234202A1 (en) * 1972-07-12 1974-01-24 Albert Ag Chem Werke Prep. of oxoalkylxanthine - this has e.g. broncholytic and fibrinolytic activity
DE2330742C2 (en) * 1973-06-16 1982-07-29 Hoechst Ag, 6000 Frankfurt 1- (Oxoalkyl) -3-methyl-7-alkylxanthines, process for their preparation and pharmaceuticals containing them
CH608236A5 (en) * 1974-01-22 1978-12-29 Wuelfing J A Fa

Also Published As

Publication number Publication date
BE838466A (en) 1976-08-11
ZA76568B (en) 1977-01-26
AR210168A1 (en) 1977-06-30
NL7601622A (en) 1976-08-24
GB1496316A (en) 1977-12-30
CH621789A5 (en) 1981-02-27
FR2301258A1 (en) 1976-09-17
JPS51110598A (en) 1976-09-30
ATA89776A (en) 1977-08-15
DE2507555A1 (en) 1976-09-02
FI760418A (en) 1976-08-22
DK72676A (en) 1976-08-22
HU174656B (en) 1980-02-28
FR2301258B1 (en) 1978-11-17
AT342617B (en) 1978-04-10
IE43978B1 (en) 1981-07-15
AU1133876A (en) 1977-09-01
AU506542B2 (en) 1980-01-10
ES445301A1 (en) 1977-06-01
YU37276A (en) 1982-08-31
AR208755A1 (en) 1977-02-28
SE7601455L (en) 1976-08-22

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