IE43488L - Guanidines. - Google Patents
Guanidines.Info
- Publication number
- IE43488L IE43488L IE761510A IE151076A IE43488L IE 43488 L IE43488 L IE 43488L IE 761510 A IE761510 A IE 761510A IE 151076 A IE151076 A IE 151076A IE 43488 L IE43488 L IE 43488L
- Authority
- IE
- Ireland
- Prior art keywords
- compounds
- bicyclo
- rhinoviruses
- gb1492678a
- ncnr
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/72—Nitrogen atoms
- C07D213/75—Amino or imino radicals, acylated by carboxylic or carbonic acids, or by sulfur or nitrogen analogues thereof, e.g. carbamates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Oncology (AREA)
- General Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Animal Behavior & Ethology (AREA)
- Virology (AREA)
- Communicable Diseases (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Pyridine Compounds (AREA)
Abstract
The compounds correspond to the formula: <IMAGE> wherein R<1> and R<2> have the meanings given in Claim 1. They are prepared by the action of ammonia on a thiourea R<1>NHC(S)NHR<2> or on a thiouronium salt thereof in the presence of a catalyst or on a carbodiimide R<1>NCNR<2>; resulting bicyclo(2,2,1)-hept-5-enyl compounds can be reduced to the bicyclo(2,2,1)heptanyl compounds. The compounds and their salts have an antiviral activity, especially against rhinoviruses; they can be used for the treatment of rhinovirus infections, as well as for the specific suppression of growth of rhinoviruses in diagnostic investigations and in hospital laboratories.
[GB1492678A]
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB33435/75A GB1492678A (en) | 1975-08-11 | 1975-08-11 | Guanidine derivatives |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| IE43488L true IE43488L (en) | 1977-02-11 |
| IE43488B1 IE43488B1 (en) | 1981-03-11 |
Family
ID=10352924
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IE1510/76A IE43488B1 (en) | 1975-08-11 | 1976-07-08 | Guanidine derivatives |
Country Status (17)
| Country | Link |
|---|---|
| JP (1) | JPS5225743A (en) |
| AT (1) | AT351045B (en) |
| AU (1) | AU497534B2 (en) |
| BE (1) | BE845052A (en) |
| CA (1) | CA1087180A (en) |
| CH (1) | CH625207A5 (en) |
| DE (1) | DE2635932A1 (en) |
| DK (1) | DK362576A (en) |
| FI (1) | FI762158A (en) |
| FR (1) | FR2320736A1 (en) |
| GB (1) | GB1492678A (en) |
| IE (1) | IE43488B1 (en) |
| NL (1) | NL7608903A (en) |
| NO (1) | NO143993C (en) |
| PL (1) | PL98956B1 (en) |
| SE (1) | SE7608929L (en) |
| ZA (1) | ZA764126B (en) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ZA829068B (en) * | 1980-07-01 | 1983-02-23 | Nat Res Dev | Prostaglandins |
| US4628061A (en) * | 1981-12-23 | 1986-12-09 | National Research Development Corporation | Prostaglandins |
| JPS59501110A (en) * | 1982-06-21 | 1984-06-28 | インステイテユ−ト オルガニチエスコゴ シンテザアカデミイ ナウク ラトビスコイ エスエスア−ル | Pharmaceutical compositions with antitumor activity |
| US20060100225A1 (en) * | 2004-03-23 | 2006-05-11 | Xi Chen | Heteroaryl guanidines; inhibitors of viral replication |
-
1975
- 1975-08-11 GB GB33435/75A patent/GB1492678A/en not_active Expired
-
1976
- 1976-07-08 IE IE1510/76A patent/IE43488B1/en unknown
- 1976-07-12 CA CA256,739A patent/CA1087180A/en not_active Expired
- 1976-07-12 ZA ZA764126A patent/ZA764126B/en unknown
- 1976-07-16 AU AU15956/76A patent/AU497534B2/en not_active Expired
- 1976-07-28 FI FI762158A patent/FI762158A/fi not_active Application Discontinuation
- 1976-08-04 PL PL1976191619A patent/PL98956B1/en unknown
- 1976-08-10 NO NO762774A patent/NO143993C/en unknown
- 1976-08-10 CH CH1019576A patent/CH625207A5/en not_active IP Right Cessation
- 1976-08-10 AT AT592976A patent/AT351045B/en not_active IP Right Cessation
- 1976-08-10 FR FR7624440A patent/FR2320736A1/en active Granted
- 1976-08-10 DE DE19762635932 patent/DE2635932A1/en not_active Withdrawn
- 1976-08-10 SE SE7608929A patent/SE7608929L/en not_active Application Discontinuation
- 1976-08-10 BE BE169700A patent/BE845052A/en unknown
- 1976-08-11 DK DK362576A patent/DK362576A/en not_active Application Discontinuation
- 1976-08-11 NL NL7608903A patent/NL7608903A/en not_active Application Discontinuation
- 1976-08-11 JP JP51095896A patent/JPS5225743A/en active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| ZA764126B (en) | 1977-06-29 |
| NO143993C (en) | 1981-05-27 |
| NL7608903A (en) | 1977-02-15 |
| GB1492678A (en) | 1977-11-23 |
| CA1087180A (en) | 1980-10-07 |
| BE845052A (en) | 1977-02-10 |
| AU1595676A (en) | 1978-01-19 |
| AU497534B2 (en) | 1978-12-14 |
| FR2320736B1 (en) | 1980-11-07 |
| CH625207A5 (en) | 1981-09-15 |
| AT351045B (en) | 1979-07-10 |
| NO762774L (en) | 1977-02-14 |
| SE7608929L (en) | 1977-02-12 |
| IE43488B1 (en) | 1981-03-11 |
| DE2635932A1 (en) | 1977-03-03 |
| FR2320736A1 (en) | 1977-03-11 |
| ATA592976A (en) | 1978-12-15 |
| NO143993B (en) | 1981-02-16 |
| JPS5225743A (en) | 1977-02-25 |
| FI762158A (en) | 1977-02-12 |
| PL98956B1 (en) | 1978-06-30 |
| DK362576A (en) | 1977-02-12 |
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