IE43453L - 15-(1,3-benzodioxan-2-yl)-16,17,19,20-pentanor prostanoic¹acid derivatives - Google Patents

15-(1,3-benzodioxan-2-yl)-16,17,19,20-pentanor prostanoic¹acid derivatives

Info

Publication number
IE43453L
IE43453L IE760394A IE39476A IE43453L IE 43453 L IE43453 L IE 43453L IE 760394 A IE760394 A IE 760394A IE 39476 A IE39476 A IE 39476A IE 43453 L IE43453 L IE 43453L
Authority
IE
Ireland
Prior art keywords
formula
compounds
prepared
image
derivatives
Prior art date
Application number
IE760394A
Other versions
IE43453B1 (en
Original Assignee
Schering Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Schering Ag filed Critical Schering Ag
Publication of IE43453L publication Critical patent/IE43453L/en
Publication of IE43453B1 publication Critical patent/IE43453B1/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D319/00—Heterocyclic compounds containing six-membered rings having two oxygen atoms as the only ring hetero atoms
    • C07D319/04—1,3-Dioxanes; Hydrogenated 1,3-dioxanes
    • C07D319/08—1,3-Dioxanes; Hydrogenated 1,3-dioxanes condensed with carbocyclic rings or ring systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic System
    • C07F9/02—Phosphorus compounds
    • C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/655—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having oxygen atoms, with or without sulfur, selenium, or tellurium atoms, as the only ring hetero atoms
    • C07F9/6552—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having oxygen atoms, with or without sulfur, selenium, or tellurium atoms, as the only ring hetero atoms the oxygen atom being part of a six-membered ring
    • C07F9/65522—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having oxygen atoms, with or without sulfur, selenium, or tellurium atoms, as the only ring hetero atoms the oxygen atom being part of a six-membered ring condensed with carbocyclic rings or carbocyclic ring systems

Abstract

1,3-Benzodioxane-prostanoic acid derivatives of the formula I and their antipodes and racemates <IMAGE> in which the substituents are defined in Claim 1, are prepared. These compounds are obtained by reacting lactols of the formula II with a Wittig reagent of the formula Ph3P=CH-(CH2)3-COR1 to introduce the side chain located in position 8. Likewise, the corresponding 9-keto compounds are prepared from compounds of the formula I which have a hydroxyl group in position 9. The compounds have prostaglandin-like properties and can be used for the same purposes as known prostaglandins. <IMAGE> [GB1546442A]
IE394/76A 1975-02-27 1976-02-27 New 15-(1,3-benzodioxan-2-yl)-16,17,18,19,20-pentanor prostanoic acid derivatives and process for their manufacture IE43453B1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19752508826 DE2508826A1 (en) 1975-02-27 1975-02-27 NEW 1,3-BENZODIOXANE PROSTANIC ACID DERIVATIVES AND THE PROCESS FOR THEIR PRODUCTION

Publications (2)

Publication Number Publication Date
IE43453L true IE43453L (en) 1976-08-27
IE43453B1 IE43453B1 (en) 1981-02-25

Family

ID=5940126

Family Applications (1)

Application Number Title Priority Date Filing Date
IE394/76A IE43453B1 (en) 1975-02-27 1976-02-27 New 15-(1,3-benzodioxan-2-yl)-16,17,18,19,20-pentanor prostanoic acid derivatives and process for their manufacture

Country Status (14)

Country Link
JP (1) JPS51125393A (en)
AT (1) AT351188B (en)
AU (1) AU503922B2 (en)
BE (1) BE839027A (en)
CA (1) CA1087178A (en)
CH (1) CH625236A5 (en)
DE (1) DE2508826A1 (en)
DK (1) DK39976A (en)
FR (1) FR2302089A1 (en)
GB (1) GB1546442A (en)
IE (1) IE43453B1 (en)
LU (1) LU74432A1 (en)
NL (1) NL7601847A (en)
SE (1) SE424552B (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE7902817L (en) * 1978-05-03 1979-11-04 Roussel Uclaf SUBSTITUTED / 4H / 1,3-BENZODIOXINE-2-CARBOXYLIC ACID DERIVATIVES, PREPARATION AND USE OF THESE AS MEDICINES AND PHARMACEUTICAL COMPOSITIONS CONTAINING THESE
FR2460945A2 (en) * 1979-07-06 1981-01-30 Roussel Uclaf 6-Chloro-2,4,4-tri:methyl-4H-1,3-benzodioxin-2-carboxylic acid - useful in treatment of hyperlipidaemia, angina and cardiac insufficiency

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2328131C3 (en) 1973-05-30 1986-11-13 Schering AG, 1000 Berlin und 4709 Bergkamen New process for the production of prostaglandin-F ↓ 2 ↓↓ α ↓ and its analogues

Also Published As

Publication number Publication date
GB1546442A (en) 1979-05-23
SE424552B (en) 1982-07-26
FR2302089A1 (en) 1976-09-24
AU503922B2 (en) 1979-09-27
NL7601847A (en) 1976-08-31
IE43453B1 (en) 1981-02-25
CH625236A5 (en) 1981-09-15
ATA143276A (en) 1978-12-15
DE2508826A1 (en) 1976-09-09
BE839027A (en) 1976-08-27
CA1087178A (en) 1980-10-07
AT351188B (en) 1979-07-10
SE7602500L (en) 1976-08-30
JPS51125393A (en) 1976-11-01
AU1099876A (en) 1977-08-18
FR2302089B1 (en) 1980-06-13
LU74432A1 (en) 1976-08-13
DK39976A (en) 1976-08-28

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