IE42821L - PREPARING TETRAHYDRO-THIENO [3,2-c] AND [2,3-c] PYRIDINE¹DERIVATIVES - Google Patents
PREPARING TETRAHYDRO-THIENO [3,2-c] AND [2,3-c] PYRIDINE¹DERIVATIVESInfo
- Publication number
- IE42821L IE42821L IE761079A IE107976A IE42821L IE 42821 L IE42821 L IE 42821L IE 761079 A IE761079 A IE 761079A IE 107976 A IE107976 A IE 107976A IE 42821 L IE42821 L IE 42821L
- Authority
- IE
- Ireland
- Prior art keywords
- tetrahydro
- thieno
- pyridine
- formula
- pyridine derivatives
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
- C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D495/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
PROCESS FOR THE PREPARATION OF TETRAHYDRO-THIENO3,2-C!- AND 2,3-C!PYRIDINE DERIVATIVES. This invention relates to a process for the preparation of tetrahydro-thieno 3,2-c!pyridine derivatives of the formula (Ia) and their isomeris tetrahydro-thieno 2,3-c!pyridine derivatives in which R1 represents hydrogen, a lower alkyl or alkoxy radical, an aryl radical or an aralkyl radical; R2 and R3 represent hydrogen, halogen, a lower alkyl or alkoxy group, a di(loweralkyl)amino, nitro, cyano or acetamido group or, together with the phenyl nucleus to which they are attached, form a polycyclic aromatic ring, comprising reacting a tetrahydrothieno3,2-c!pyridine derivative of the formula: (IIa) or a derivative of its isomer, tetrahydro2,3-c!pyridine, with formaldehyde H-CHO and a phenol of the formula: (III).
PROCESS FOR THE PREPARATION OF TETRAHYDRO-THIENO¢3,2-C!- AND ¢2,3-C!PYRIDINE DERIVATIVES. This invention relates to a process for the preparation of tetrahydro-thieno ¢3,2-c!pyridine derivatives of the formula (Ia) and their isomeris tetrahydro-thieno ¢2,3-c!pyridine derivatives in which R1 represents hydrogen, a lower alkyl or alkoxy radical, an aryl radical or an aralkyl radical; R2 and R3 represent hydrogen, halogen, a lower alkyl or alkoxy group, a di(loweralkyl)amino, nitro, cyano or acetamido group or, together with the phenyl nucleus to which they are attached, form a polycyclic aromatic ring, comprising reacting a tetrahydrothieno¢3,2-c!pyridine derivative of the formula: (IIa) or a derivative of its isomer, tetrahydro¢2,3-c!pyridine, with formaldehyde H-CHO and a phenol of the formula: (III).
[CA1071634A]
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR7521549A FR2317303A1 (en) | 1975-07-09 | 1975-07-09 | PROCESS FOR PREPARING TETRAHYDROTHIENO (3,2-C) AND (2,3-C) PYRIDINE DERIVATIVES |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| IE42821L true IE42821L (en) | 1977-01-09 |
| IE42821B1 IE42821B1 (en) | 1980-10-22 |
Family
ID=9157715
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IE1079/76A IE42821B1 (en) | 1975-07-09 | 1976-05-21 | Improvements in or relating to a process for the preparation of tetrahydro-thieno /3,2-c/- and /2,3-c/pyridine derivatives |
Country Status (26)
| Country | Link |
|---|---|
| JP (1) | JPS5236691A (en) |
| AR (1) | AR211019A1 (en) |
| AT (1) | AT348526B (en) |
| BE (1) | BE843822A (en) |
| CA (1) | CA1071634A (en) |
| CH (1) | CH609349A5 (en) |
| DD (1) | DD125081A5 (en) |
| DE (1) | DE2630474A1 (en) |
| DK (1) | DK141333B (en) |
| ES (1) | ES448404A1 (en) |
| FR (1) | FR2317303A1 (en) |
| GB (1) | GB1544093A (en) |
| GR (1) | GR59812B (en) |
| HU (1) | HU172280B (en) |
| IE (1) | IE42821B1 (en) |
| IL (1) | IL49641A (en) |
| LU (1) | LU74674A1 (en) |
| MX (1) | MX3224E (en) |
| NL (1) | NL7605362A (en) |
| PH (1) | PH12311A (en) |
| PL (1) | PL100685B1 (en) |
| PT (1) | PT65072B (en) |
| SE (1) | SE421699B (en) |
| SU (1) | SU628819A3 (en) |
| YU (1) | YU40137B (en) |
| ZA (1) | ZA763219B (en) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS5665315A (en) * | 1979-11-02 | 1981-06-03 | Nec Corp | Magnetic recording and inspecting system |
| DE3736664A1 (en) * | 1987-10-29 | 1989-05-11 | Boehringer Ingelheim Kg | TETRAHYDRO-FURO- AND -THIENO (2,3-C) PYRIDINE, THEIR USE AS A MEDICAMENT AND METHOD FOR THE PRODUCTION THEREOF |
| NZ233654A (en) * | 1989-05-18 | 1993-02-25 | Bristol Myers Squibb Co | 2-aminomethyl-5-aminophenol derivatives; hair dye compositions containing them |
-
1975
- 1975-07-09 FR FR7521549A patent/FR2317303A1/en active Granted
-
1976
- 1976-03-31 LU LU74674A patent/LU74674A1/xx unknown
- 1976-04-01 CH CH404576A patent/CH609349A5/en not_active IP Right Cessation
- 1976-04-21 GR GR50593A patent/GR59812B/en unknown
- 1976-04-23 YU YU1030/76A patent/YU40137B/en unknown
- 1976-05-06 PT PT65072A patent/PT65072B/en unknown
- 1976-05-19 NL NL7605362A patent/NL7605362A/en not_active Application Discontinuation
- 1976-05-21 IE IE1079/76A patent/IE42821B1/en unknown
- 1976-05-24 IL IL49641A patent/IL49641A/en unknown
- 1976-05-31 ES ES448404A patent/ES448404A1/en not_active Expired
- 1976-06-01 ZA ZA763219A patent/ZA763219B/en unknown
- 1976-06-03 AR AR263501A patent/AR211019A1/en active
- 1976-06-09 SU SU762366005A patent/SU628819A3/en active
- 1976-06-10 CA CA254,573A patent/CA1071634A/en not_active Expired
- 1976-06-16 MX MX000320U patent/MX3224E/en unknown
- 1976-07-01 DK DK297876AA patent/DK141333B/en not_active IP Right Cessation
- 1976-07-01 PH PH7618641A patent/PH12311A/en unknown
- 1976-07-05 AT AT489876A patent/AT348526B/en not_active IP Right Cessation
- 1976-07-06 BE BE168664A patent/BE843822A/en not_active IP Right Cessation
- 1976-07-07 SE SE7607762A patent/SE421699B/en not_active IP Right Cessation
- 1976-07-07 DE DE19762630474 patent/DE2630474A1/en active Pending
- 1976-07-07 DD DD193745A patent/DD125081A5/xx unknown
- 1976-07-08 JP JP51081441A patent/JPS5236691A/en active Granted
- 1976-07-08 PL PL1976191016A patent/PL100685B1/en unknown
- 1976-07-08 GB GB28511/76A patent/GB1544093A/en not_active Expired
- 1976-07-09 HU HU76PA00001255A patent/HU172280B/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| CA1071634A (en) | 1980-02-12 |
| CH609349A5 (en) | 1979-02-28 |
| MX3224E (en) | 1980-07-28 |
| SU628819A3 (en) | 1978-10-15 |
| DK297876A (en) | 1977-01-10 |
| DK141333B (en) | 1980-02-25 |
| PT65072B (en) | 1977-09-13 |
| AT348526B (en) | 1979-02-26 |
| IL49641A0 (en) | 1976-07-30 |
| SE421699B (en) | 1982-01-25 |
| FR2317303A1 (en) | 1977-02-04 |
| NL7605362A (en) | 1977-01-11 |
| BE843822A (en) | 1977-01-06 |
| FR2317303B1 (en) | 1977-12-16 |
| IL49641A (en) | 1978-08-31 |
| AR211019A1 (en) | 1977-10-14 |
| DE2630474A1 (en) | 1977-01-13 |
| IE42821B1 (en) | 1980-10-22 |
| HU172280B (en) | 1978-07-28 |
| JPS5236691A (en) | 1977-03-22 |
| AU1568676A (en) | 1977-03-31 |
| PT65072A (en) | 1976-06-01 |
| GR59812B (en) | 1978-03-01 |
| LU74674A1 (en) | 1976-09-01 |
| YU40137B (en) | 1985-08-31 |
| ZA763219B (en) | 1977-05-25 |
| YU103076A (en) | 1982-02-28 |
| DD125081A5 (en) | 1977-03-30 |
| PL100685B1 (en) | 1978-10-31 |
| GB1544093A (en) | 1979-04-11 |
| PH12311A (en) | 1979-01-16 |
| DK141333C (en) | 1980-08-25 |
| ATA489876A (en) | 1978-07-15 |
| SE7607762L (en) | 1977-01-10 |
| ES448404A1 (en) | 1977-07-01 |
| JPS5310077B2 (en) | 1978-04-11 |
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