CH609349A5 - Process for the preparation of tetrahydrothieno[3,2-c] and [2,3-c]pyridine derivatives - Google Patents
Process for the preparation of tetrahydrothieno[3,2-c] and [2,3-c]pyridine derivativesInfo
- Publication number
- CH609349A5 CH609349A5 CH404576A CH404576A CH609349A5 CH 609349 A5 CH609349 A5 CH 609349A5 CH 404576 A CH404576 A CH 404576A CH 404576 A CH404576 A CH 404576A CH 609349 A5 CH609349 A5 CH 609349A5
- Authority
- CH
- Switzerland
- Prior art keywords
- lower alkyl
- tetrahydrothieno
- preparation
- radical
- derivative
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
- C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D495/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
By reaction of a derivative of tetrahydrothieno[3,2-c]pyridine or of a derivative of its [2,3-c] isomer with formaldehyde and a phenol, compounds of the general formula (Ia) or (Ib) below are obtained. The hydroxyl OH is in position 2 or in position 4, R1 represents hydrogen, a lower alkyl or alkoxy radical, or an aryl or aralkyl radical, R2 and R3 represent hydrogen, a halogen, a lower alkyl or alkoxy radical, a di(lower alkyl)amino radical, or a nitro, cyano or acetamido group, or else form together and with the phenyl ring to which they are fixed, a polycyclic aromatic ring, R2 and R3 being in position 3, 4, 5, or 6 when OH is in position 2 and being in position 3 and 5 and different from hydrogen when OH is in position 4. The compounds obtained have therapeutic properties and can additionally be used as intermediates in the preparation of other derivatives which can be used in the chemical and pharmaceutical industry. <IMAGE>
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR7521549A FR2317303A1 (en) | 1975-07-09 | 1975-07-09 | PROCESS FOR PREPARING TETRAHYDROTHIENO (3,2-C) AND (2,3-C) PYRIDINE DERIVATIVES |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CH609349A5 true CH609349A5 (en) | 1979-02-28 |
Family
ID=9157715
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CH404576A CH609349A5 (en) | 1975-07-09 | 1976-04-01 | Process for the preparation of tetrahydrothieno[3,2-c] and [2,3-c]pyridine derivatives |
Country Status (26)
| Country | Link |
|---|---|
| JP (1) | JPS5236691A (en) |
| AR (1) | AR211019A1 (en) |
| AT (1) | AT348526B (en) |
| BE (1) | BE843822A (en) |
| CA (1) | CA1071634A (en) |
| CH (1) | CH609349A5 (en) |
| DD (1) | DD125081A5 (en) |
| DE (1) | DE2630474A1 (en) |
| DK (1) | DK141333B (en) |
| ES (1) | ES448404A1 (en) |
| FR (1) | FR2317303A1 (en) |
| GB (1) | GB1544093A (en) |
| GR (1) | GR59812B (en) |
| HU (1) | HU172280B (en) |
| IE (1) | IE42821B1 (en) |
| IL (1) | IL49641A (en) |
| LU (1) | LU74674A1 (en) |
| MX (1) | MX3224E (en) |
| NL (1) | NL7605362A (en) |
| PH (1) | PH12311A (en) |
| PL (1) | PL100685B1 (en) |
| PT (1) | PT65072B (en) |
| SE (1) | SE421699B (en) |
| SU (1) | SU628819A3 (en) |
| YU (1) | YU40137B (en) |
| ZA (1) | ZA763219B (en) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS5665315A (en) * | 1979-11-02 | 1981-06-03 | Nec Corp | Magnetic recording and inspecting system |
| DE3736664A1 (en) * | 1987-10-29 | 1989-05-11 | Boehringer Ingelheim Kg | TETRAHYDRO-FURO- AND -THIENO (2,3-C) PYRIDINE, THEIR USE AS A MEDICAMENT AND METHOD FOR THE PRODUCTION THEREOF |
| NZ233654A (en) * | 1989-05-18 | 1993-02-25 | Bristol Myers Squibb Co | 2-aminomethyl-5-aminophenol derivatives; hair dye compositions containing them |
-
1975
- 1975-07-09 FR FR7521549A patent/FR2317303A1/en active Granted
-
1976
- 1976-03-31 LU LU74674A patent/LU74674A1/xx unknown
- 1976-04-01 CH CH404576A patent/CH609349A5/en not_active IP Right Cessation
- 1976-04-21 GR GR50593A patent/GR59812B/en unknown
- 1976-04-23 YU YU1030/76A patent/YU40137B/en unknown
- 1976-05-06 PT PT65072A patent/PT65072B/en unknown
- 1976-05-19 NL NL7605362A patent/NL7605362A/en not_active Application Discontinuation
- 1976-05-21 IE IE1079/76A patent/IE42821B1/en unknown
- 1976-05-24 IL IL49641A patent/IL49641A/en unknown
- 1976-05-31 ES ES448404A patent/ES448404A1/en not_active Expired
- 1976-06-01 ZA ZA763219A patent/ZA763219B/en unknown
- 1976-06-03 AR AR263501A patent/AR211019A1/en active
- 1976-06-09 SU SU762366005A patent/SU628819A3/en active
- 1976-06-10 CA CA254,573A patent/CA1071634A/en not_active Expired
- 1976-06-16 MX MX000320U patent/MX3224E/en unknown
- 1976-07-01 DK DK297876AA patent/DK141333B/en not_active IP Right Cessation
- 1976-07-01 PH PH7618641A patent/PH12311A/en unknown
- 1976-07-05 AT AT489876A patent/AT348526B/en not_active IP Right Cessation
- 1976-07-06 BE BE168664A patent/BE843822A/en not_active IP Right Cessation
- 1976-07-07 SE SE7607762A patent/SE421699B/en not_active IP Right Cessation
- 1976-07-07 DE DE19762630474 patent/DE2630474A1/en active Pending
- 1976-07-07 DD DD193745A patent/DD125081A5/xx unknown
- 1976-07-08 JP JP51081441A patent/JPS5236691A/en active Granted
- 1976-07-08 PL PL1976191016A patent/PL100685B1/en unknown
- 1976-07-08 GB GB28511/76A patent/GB1544093A/en not_active Expired
- 1976-07-09 HU HU76PA00001255A patent/HU172280B/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| CA1071634A (en) | 1980-02-12 |
| MX3224E (en) | 1980-07-28 |
| SU628819A3 (en) | 1978-10-15 |
| DK297876A (en) | 1977-01-10 |
| DK141333B (en) | 1980-02-25 |
| PT65072B (en) | 1977-09-13 |
| AT348526B (en) | 1979-02-26 |
| IL49641A0 (en) | 1976-07-30 |
| SE421699B (en) | 1982-01-25 |
| FR2317303A1 (en) | 1977-02-04 |
| NL7605362A (en) | 1977-01-11 |
| BE843822A (en) | 1977-01-06 |
| FR2317303B1 (en) | 1977-12-16 |
| IL49641A (en) | 1978-08-31 |
| AR211019A1 (en) | 1977-10-14 |
| DE2630474A1 (en) | 1977-01-13 |
| IE42821B1 (en) | 1980-10-22 |
| HU172280B (en) | 1978-07-28 |
| JPS5236691A (en) | 1977-03-22 |
| IE42821L (en) | 1977-01-09 |
| AU1568676A (en) | 1977-03-31 |
| PT65072A (en) | 1976-06-01 |
| GR59812B (en) | 1978-03-01 |
| LU74674A1 (en) | 1976-09-01 |
| YU40137B (en) | 1985-08-31 |
| ZA763219B (en) | 1977-05-25 |
| YU103076A (en) | 1982-02-28 |
| DD125081A5 (en) | 1977-03-30 |
| PL100685B1 (en) | 1978-10-31 |
| GB1544093A (en) | 1979-04-11 |
| PH12311A (en) | 1979-01-16 |
| DK141333C (en) | 1980-08-25 |
| ATA489876A (en) | 1978-07-15 |
| SE7607762L (en) | 1977-01-10 |
| ES448404A1 (en) | 1977-07-01 |
| JPS5310077B2 (en) | 1978-04-11 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PL | Patent ceased |