IE42230L - Pharmaceutical combination preparation - Google Patents
Pharmaceutical combination preparationInfo
- Publication number
- IE42230L IE42230L IE760012A IE1276A IE42230L IE 42230 L IE42230 L IE 42230L IE 760012 A IE760012 A IE 760012A IE 1276 A IE1276 A IE 1276A IE 42230 L IE42230 L IE 42230L
- Authority
- IE
- Ireland
- Prior art keywords
- alkyl
- carbamoyl
- lower alkyl
- ureido
- optionally substituted
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
- A61K31/403—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
- A61K31/404—Indoles, e.g. pindolol
- A61K31/405—Indole-alkanecarboxylic acids; Derivatives thereof, e.g. tryptophan, indomethacin
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicinal Preparation (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Indole Compounds (AREA)
Abstract
1531091 Pharmaceutical preparations CIBA GEIGY AG 5 Jan 1976 [6 Jan 1975] 00144/76 Heading A5B Pharmaceutical preparations useful as hypnotics for inducing and prolonging sleep and for releiving sleep disorders contain as pharmacological active compounds a compound of the formula: wherein Ar 1 represents a monocyclic or polycyclic, carbocyclic or heterocyclic radical which contains at least one ring of aromatic character and which is bonded to the oxygen atom via a ring carbon atom, said radicals being unsubstituted or substituted by one or two substituents selected from lower (i.e. C 1-7 ) alkyl, lower alkenyl or lower alkinyl, said lower alkyl, lower alkenyl or lower alkinyl being optionally substituted by lower alkoxy, lower alkylthio or halogen, carboxy, lower alkoxycarbonyl, carbamoyl, N-lower alkylated carbamoyl, amino, lower alkanoylamino, lower alkoxy-carbonylamino, ureido, N-lower alkyl-ureido, N', N'-di-lower alkyl-ureido or lower alkylsulphonylamino, or substituted by one or two substituents selected from monocyclic or polycyclic cycloalkyl, hydroxyl, lower alkoxy, lower alkenyloxy, lower alkinyloxy, mercapto, lower alkylthio, lower alkenylthio, halogen, lower alkanoyloxy, lower alkanoyl, lower alkoxycarbonyl, carbamoyl, N-lower alkylcarbamoyl, N, N-di-lower alkylcarbamoyl, cyano, nitro, amino, lower alkanoylamino, lower alkoxycarbonylamino, ureido, N'-lower alkyl-ureido, N', N'-di-lower alkyl-ureido, lower alkylsulphonylureido, lower alkyl sulphonylamino, N-lower alkylamino or N, N-di-lower alkylamino, optionally unsubstituted N, N-lower alkyleneamino, N, N-azalower alkyleneamino, N, N-oxa-lower alkylene-amino or N, N-thia-lower alkyleneamino, R 1 denotes lower alkyl, lower alkenyl, lower alkinyl, cycloalkyl or phenyl-lower alkyl, said lower alkyl, lower alkenyl, lower alkinyl or cycloalkyl being optionally substituted by lower alkyl, phenoxy or pyridyloxy optionally substituted by carbamoyl, N-lower alkylcarbamoyl or N, N-di-lower alkyl-carbamoyl, or optionally substituted by carboxyl, lower alkoxycarbonyl carbamoyl, N-lower alkylcarbamoyl, N, N-di-lower alkyl carbamoyl or cyano, said phenyl-lower alkyl being optionally substituted in the aromatic part by carboxyl, lower alkoxycarbonyl, carbamoyl, N- lower-alkyl carbamoyl or N, N-lower alkyl carbamoyl, R 2 represents hydrogen, lower alkanoyl or benzoyl, or a compound of the formula: wherein R 1 and R 2 have the meanings defined under formula (I), Ar 2 represents a monocyclic or polycyclic carbocyclic radical which contains at least one ring of aromatic character, said monocyclic or polycyclic carbocyclic radical being unsubstituted or substituted as defined under formula (I) and R 3 denotes hydrogen or lower alkyl, or a salt of such compounds, which can be used pharmaceutically, as a beta-receptor-blocking active compound, and L-tryptophan or a non- toxic salt thereof which can be used pharmaceutically. The preparations may be administered orally, rectally or parenterally in the form of tablets, dragÚes, capsules, suppositories and solutions.
[GB1531091A]
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CH7275 | 1975-01-06 |
Publications (2)
Publication Number | Publication Date |
---|---|
IE42230L true IE42230L (en) | 1976-07-06 |
IE42230B1 IE42230B1 (en) | 1980-07-02 |
Family
ID=4178653
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IE12/76A IE42230B1 (en) | 1975-01-06 | 1976-01-05 | Pharmaceutical combination preparations |
Country Status (13)
Country | Link |
---|---|
JP (1) | JPS5191336A (en) |
AU (1) | AU500434B2 (en) |
BE (1) | BE837295A (en) |
CA (1) | CA1063026A (en) |
DE (1) | DE2600070A1 (en) |
ES (1) | ES444083A1 (en) |
FR (1) | FR2296414A1 (en) |
GB (1) | GB1531091A (en) |
IE (1) | IE42230B1 (en) |
IL (1) | IL48786A (en) |
NL (1) | NL7600044A (en) |
NZ (1) | NZ179621A (en) |
ZA (1) | ZA7627B (en) |
Families Citing this family (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4433004A (en) * | 1979-07-11 | 1984-02-21 | Tokyo Shibaura Denki Kabushiki Kaisha | Semiconductor device and a method for manufacturing the same |
-
1975
- 1975-12-22 NZ NZ179621A patent/NZ179621A/en unknown
-
1976
- 1976-01-02 FR FR7600015A patent/FR2296414A1/en active Granted
- 1976-01-02 DE DE19762600070 patent/DE2600070A1/en not_active Withdrawn
- 1976-01-02 CA CA242,911A patent/CA1063026A/en not_active Expired
- 1976-01-05 ES ES444083A patent/ES444083A1/en not_active Expired
- 1976-01-05 IE IE12/76A patent/IE42230B1/en unknown
- 1976-01-05 IL IL48786A patent/IL48786A/en unknown
- 1976-01-05 BE BE163297A patent/BE837295A/en unknown
- 1976-01-05 NL NL7600044A patent/NL7600044A/en not_active Application Discontinuation
- 1976-01-05 AU AU10003/76A patent/AU500434B2/en not_active Expired
- 1976-01-05 ZA ZA00760027A patent/ZA7627B/en unknown
- 1976-01-05 GB GB144/76A patent/GB1531091A/en not_active Expired
- 1976-01-06 JP JP51000125A patent/JPS5191336A/ja active Pending
Also Published As
Publication number | Publication date |
---|---|
NZ179621A (en) | 1978-04-28 |
IL48786A0 (en) | 1976-03-31 |
IE42230B1 (en) | 1980-07-02 |
JPS5191336A (en) | 1976-08-10 |
CA1063026A (en) | 1979-09-25 |
BE837295A (en) | 1976-07-05 |
DE2600070A1 (en) | 1976-07-15 |
IL48786A (en) | 1978-12-17 |
FR2296414B1 (en) | 1981-12-31 |
ES444083A1 (en) | 1977-05-01 |
AU500434B2 (en) | 1979-05-24 |
ZA7627B (en) | 1976-12-29 |
AU1000376A (en) | 1977-07-14 |
FR2296414A1 (en) | 1976-07-30 |
GB1531091A (en) | 1978-11-01 |
NL7600044A (en) | 1976-07-08 |
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