IE40886L - Quinoxalinedioxide derivatives - Google Patents

Quinoxalinedioxide derivatives

Info

Publication number
IE40886L
IE40886L IE750621A IE62175A IE40886L IE 40886 L IE40886 L IE 40886L IE 750621 A IE750621 A IE 750621A IE 62175 A IE62175 A IE 62175A IE 40886 L IE40886 L IE 40886L
Authority
IE
Ireland
Prior art keywords
lower alkyl
piperazino
group
carbamyl
hydroxy
Prior art date
Application number
IE750621A
Other versions
IE40886B1 (en
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer filed Critical Pfizer
Publication of IE40886L publication Critical patent/IE40886L/en
Publication of IE40886B1 publication Critical patent/IE40886B1/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D241/00—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings
    • C07D241/36—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings condensed with carbocyclic rings or ring systems
    • C07D241/50—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings condensed with carbocyclic rings or ring systems with hetero atoms directly attached to ring nitrogen atoms
    • C07D241/52—Oxygen atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Fodder In General (AREA)
  • Chemical And Physical Treatments For Wood And The Like (AREA)

Abstract

1450518 3-Substituted quinoxaline-2-carboxamide-1,4-dioxides PFIZER Ine 6 May 1975 [7 May 1974] 19058/75 Heading C2C Novel 3-substituted quinoxaline-2-carboxamide-1,4-dioxides having the general formula wherein X is a hydrogen atom or a substituent in the 6- or 7-position which is a halogen atom or a lower alkoxy, trifluoromethyl, methyl, lower alkyl sulphide, lower alkyl sulphoxide or lower alkyl sulphone group; Y is S, SO or SO 2 ; R 1 is a lower alkyl group substituted with a halogen atom or a hydroxy, lower alkoxy, amino, mono (lower alkyl) amino, di-(lower alkyl(amino, lower alkoxycarbonyl, carbamyl, mono- (lower alkyl)carbamyl, di-(lower alkyl)carbamyl, mercapto, sulpho, lower alkyl sulphide, lower alkyl sulphoxide, lower alkyl sulphone, acetoxy, pyrrolidino, piperidino, morpholino, thiomorpholino, piperazino, N-(lower alkyl) piperazino, N-hydroxy-(lower alkyl)piperazino, N-(lower alkanoyl) piperazino or N-carbo (lower alkoxy) piperazino group; R 2 is a hydrogen atom or a lower alkyl group; R 3 is a hydrogen atom or a phenyl, lower alkyl or substituted lower alkyl group wherein the substituent is ammo, mono-(lower alkyl)amino, di-(lower alkyl)amino, pyrrolidino, piperidino, morpholino, N-(lower alkyl)piperazino, N- hydroxy (lower alkyl)piperazino, N-(lower alkanoyl)piperazino, N-carbo (lower alkoxy)piperazino, pyrrolo, piperazino, imidazolidino, hydroxy, lower alkoxy, thio-(lower alkyl), carboxy, carbo (lower alkoxy), carbamyl, mono- (lower alkyl)carbamyl, di-(lower alkyl)carbamyl, lower alkanoyloxy or lower alkanoylamino, or R 2 and R 3 , when taken together with the nitrogen atom to which they are attached, form a pyrrolo, pyrrolidino, piperidino, morpholino, thiomorpholino, piperazino, N-(lower alkyl) piperazino, N - hydroxy(lower alkyl piperazino, N-(lower alkanoyl)piperazino or N-carbo-(lower alkoxy)piperazino group, and the pharmaceutically-acceptable acid addition salts of those compounds wherein at least one of R 1 and R 3 is a substituted lower alkyl group wherein the substituent is a basic group. The novel compounds may be used as antibacterial agents for the control of various pathogenic microorganisms and as animal growth promotants. [GB1450518A]
IE621/75A 1974-05-07 1975-03-20 3-substituted quinoxaline-2-carboxamide-1,4-dioxides IE40886B1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US46771874A 1974-05-07 1974-05-07

Publications (2)

Publication Number Publication Date
IE40886L true IE40886L (en) 1975-11-07
IE40886B1 IE40886B1 (en) 1979-09-12

Family

ID=23856860

Family Applications (1)

Application Number Title Priority Date Filing Date
IE621/75A IE40886B1 (en) 1974-05-07 1975-03-20 3-substituted quinoxaline-2-carboxamide-1,4-dioxides

Country Status (15)

Country Link
JP (1) JPS50160286A (en)
AR (1) AR210328A1 (en)
AT (1) ATA351075A (en)
AU (1) AU8053075A (en)
BE (1) BE828745A (en)
DE (1) DE2520545A1 (en)
DK (1) DK140940B (en)
ES (1) ES437053A1 (en)
FI (1) FI751328A (en)
FR (1) FR2269949B1 (en)
GB (1) GB1450518A (en)
IE (1) IE40886B1 (en)
IT (1) IT1052135B (en)
LU (1) LU72415A1 (en)
NL (1) NL7505292A (en)

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3644360A (en) * 1970-05-05 1972-02-22 Pfizer 3-substituted methylquinoxaline-2-carboxamide-1 4-dioxides

Also Published As

Publication number Publication date
AR210328A1 (en) 1977-07-29
DE2520545A1 (en) 1975-11-20
JPS50160286A (en) 1975-12-25
AU8053075A (en) 1976-10-28
IE40886B1 (en) 1979-09-12
DK171275A (en) 1975-11-08
BE828745A (en) 1975-11-05
NL7505292A (en) 1975-11-11
GB1450518A (en) 1976-09-22
FR2269949B1 (en) 1978-07-21
FI751328A (en) 1975-11-08
DK140940B (en) 1979-12-10
IT1052135B (en) 1981-06-20
DK140940C (en) 1980-05-19
FR2269949A1 (en) 1975-12-05
ES437053A1 (en) 1977-01-16
LU72415A1 (en) 1976-03-17
ATA351075A (en) 1977-07-15

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