IE40649B1 - Butyramides, their preparation and pharmaceutical compositions containing theam - Google Patents
Butyramides, their preparation and pharmaceutical compositions containing theamInfo
- Publication number
- IE40649B1 IE40649B1 IE1819/74A IE181974A IE40649B1 IE 40649 B1 IE40649 B1 IE 40649B1 IE 1819/74 A IE1819/74 A IE 1819/74A IE 181974 A IE181974 A IE 181974A IE 40649 B1 IE40649 B1 IE 40649B1
- Authority
- IE
- Ireland
- Prior art keywords
- alkyl
- acids
- butyrimidic
- pharmaceutical compositions
- theam
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C233/00—Carboxylic acid amides
- C07C233/01—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
- C07C233/16—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by singly-bound oxygen atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
1444492 Butyrimidic acids ROUSSEL UCLAF 2 Sept 1974 [3 Sept 1973] 38291/74 Heading C2C Novel butyrimidic acids of the formula wherein X<SP>1</SP> 1 , X<SP>11</SP> 1 , X<SP>1</SP> 2 and X<SP>11</SP> 2 each are H, halogen, C 1-5 alkyl, C 1-5 alkoxy, C 1-5 alkylthio, CF 3 , trifluoromethoxy, trifluoromethylthio, OH or di(C 1-5 alkyl)amino, X, Y and Z each are H or C 1-5 alkyl, R 1 is H or C 1-5 alkyl, R 2 is OH or C 1-5 alkoxy and the symbols # either both represent single C-C bonds or one represents a C-C bond and the other represents a C=C bond are prepared by reacting the corresponding butyric acids or functional derivatives thereof with compounds of the formula HN(R<SP>1</SP>)R 2 . 4 - (3 - p - Chlorobenzoyl - 2 - methylphenyl)- butyryl chloride is obtained by reacting the corresponding butyric acid with thionyl chloride. Pharmaceutical compositions, suitable for oral, parenteral, rectal or topical administration, contain the above butyrimidic acids and pharmaceutical carriers or excipients. The compounds possess analgesic and anti-inflammatory properties.
[GB1444492A]
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR7331699A FR2242077B1 (en) | 1973-09-03 | 1973-09-03 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| IE40649L IE40649L (en) | 1975-03-03 |
| IE40649B1 true IE40649B1 (en) | 1979-07-18 |
Family
ID=9124547
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IE1819/74A IE40649B1 (en) | 1973-09-03 | 1974-09-03 | Butyramides, their preparation and pharmaceutical compositions containing theam |
Country Status (19)
| Country | Link |
|---|---|
| JP (1) | JPS5050345A (en) |
| AT (1) | AT335998B (en) |
| BE (1) | BE819456A (en) |
| CA (1) | CA1030552A (en) |
| CH (1) | CH587799A5 (en) |
| DD (1) | DD116028A5 (en) |
| DE (1) | DE2442124A1 (en) |
| DK (1) | DK464674A (en) |
| ES (1) | ES429717A1 (en) |
| FR (1) | FR2242077B1 (en) |
| GB (1) | GB1444492A (en) |
| HU (1) | HU168678B (en) |
| IE (1) | IE40649B1 (en) |
| IL (1) | IL45506A (en) |
| LU (1) | LU70832A1 (en) |
| NL (1) | NL7411702A (en) |
| SE (1) | SE414496B (en) |
| SU (1) | SU576919A3 (en) |
| ZA (1) | ZA745400B (en) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB8531839D0 (en) * | 1985-12-30 | 1986-02-05 | Wellcome Found | Aryl derivatives |
| NO165341C (en) * | 1985-03-16 | 1991-01-30 | Wellcome Found | ANALOGY PROCEDURE FOR THE PREPARATION OF THERAPEUTIC ACTIVE HYDROXIC ACID AERIAL DERIVATIVES. |
| DE3869692D1 (en) * | 1987-07-29 | 1992-05-07 | Takeda Chemical Industries Ltd | CELL POLLIFERATION INHIBITOR. |
| US5028629A (en) * | 1990-03-28 | 1991-07-02 | Eli Lilly And Company | 5-Lipoxygenase inhibitors |
| AU6701694A (en) | 1993-04-16 | 1994-11-08 | Mccormick & Company, Inc. | Encapsulation compositions |
| CA2567443A1 (en) * | 2004-06-01 | 2006-01-12 | The Scripps Research Institute | Proteomic analysis |
-
1973
- 1973-09-03 FR FR7331699A patent/FR2242077B1/fr not_active Expired
-
1974
- 1974-08-05 SE SE7410046-2A patent/SE414496B/en unknown
- 1974-08-13 DD DD180466A patent/DD116028A5/xx unknown
- 1974-08-20 IL IL45506A patent/IL45506A/en unknown
- 1974-08-22 ZA ZA00745400A patent/ZA745400B/en unknown
- 1974-08-28 JP JP49098005A patent/JPS5050345A/ja active Pending
- 1974-08-30 HU HURO793A patent/HU168678B/hu unknown
- 1974-08-30 LU LU70832A patent/LU70832A1/xx unknown
- 1974-08-30 CA CA208,178A patent/CA1030552A/en not_active Expired
- 1974-09-02 GB GB3829174A patent/GB1444492A/en not_active Expired
- 1974-09-02 ES ES429717A patent/ES429717A1/en not_active Expired
- 1974-09-02 SU SU7402063057A patent/SU576919A3/en active
- 1974-09-02 BE BE148139A patent/BE819456A/en unknown
- 1974-09-02 CH CH1190174A patent/CH587799A5/xx not_active IP Right Cessation
- 1974-09-03 AT AT710474A patent/AT335998B/en not_active IP Right Cessation
- 1974-09-03 DK DK464674A patent/DK464674A/da not_active Application Discontinuation
- 1974-09-03 IE IE1819/74A patent/IE40649B1/en unknown
- 1974-09-03 DE DE2442124A patent/DE2442124A1/en not_active Withdrawn
- 1974-09-03 NL NL7411702A patent/NL7411702A/en not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| HU168678B (en) | 1976-06-28 |
| DK464674A (en) | 1975-05-05 |
| LU70832A1 (en) | 1975-06-11 |
| SU576919A3 (en) | 1977-10-15 |
| FR2242077B1 (en) | 1977-01-28 |
| DD116028A5 (en) | 1975-11-05 |
| IL45506A0 (en) | 1974-11-29 |
| NL7411702A (en) | 1975-03-05 |
| CH587799A5 (en) | 1977-05-13 |
| SE414496B (en) | 1980-08-04 |
| CA1030552A (en) | 1978-05-02 |
| ATA710474A (en) | 1976-08-15 |
| GB1444492A (en) | 1976-07-28 |
| SE7410046L (en) | 1975-03-04 |
| BE819456A (en) | 1975-03-03 |
| IL45506A (en) | 1978-07-31 |
| ZA745400B (en) | 1975-10-29 |
| IE40649L (en) | 1975-03-03 |
| ES429717A1 (en) | 1977-04-01 |
| DE2442124A1 (en) | 1975-03-06 |
| AU7260674A (en) | 1976-02-26 |
| AT335998B (en) | 1977-04-12 |
| JPS5050345A (en) | 1975-05-06 |
| FR2242077A1 (en) | 1975-03-28 |
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