IE40593B1 - Novel piperazine derivatives and compositions containing them for treating parkinson's disease - Google Patents
Novel piperazine derivatives and compositions containing them for treating parkinson's diseaseInfo
- Publication number
- IE40593B1 IE40593B1 IE254/75A IE25475A IE40593B1 IE 40593 B1 IE40593 B1 IE 40593B1 IE 254/75 A IE254/75 A IE 254/75A IE 25475 A IE25475 A IE 25475A IE 40593 B1 IE40593 B1 IE 40593B1
- Authority
- IE
- Ireland
- Prior art keywords
- disease
- compositions containing
- piperazine derivatives
- treating parkinson
- novel piperazine
- Prior art date
Links
- 150000004885 piperazines Chemical class 0.000 title abstract 2
- 208000018737 Parkinson disease Diseases 0.000 title 1
- 239000000203 mixture Substances 0.000 title 1
- 229940066771 systemic antihistamines piperazine derivative Drugs 0.000 title 1
- MPCHQYWZAVTABQ-UHFFFAOYSA-N 2-(chloromethyl)naphthalene Chemical compound C1=CC=CC2=CC(CCl)=CC=C21 MPCHQYWZAVTABQ-UHFFFAOYSA-N 0.000 abstract 1
- 208000027089 Parkinsonian disease Diseases 0.000 abstract 1
- 206010034010 Parkinsonism Diseases 0.000 abstract 1
- -1 beta -Naphthylmethyl piperazinyl Chemical group 0.000 abstract 1
- 230000005494 condensation Effects 0.000 abstract 1
- 238000009833 condensation Methods 0.000 abstract 1
- GLUUGHFHXGJENI-UHFFFAOYSA-N diethylenediamine Natural products C1CNCCN1 GLUUGHFHXGJENI-UHFFFAOYSA-N 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/02—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms containing only hydrogen and carbon atoms in addition to the ring hetero elements
- C07D295/027—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms containing only hydrogen and carbon atoms in addition to the ring hetero elements containing only one hetero ring
- C07D295/03—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms containing only hydrogen and carbon atoms in addition to the ring hetero elements containing only one hetero ring with the ring nitrogen atoms directly attached to acyclic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
- C07D295/06—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by halogen atoms or nitro radicals
- C07D295/073—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by halogen atoms or nitro radicals with the ring nitrogen atoms and the substituents separated by carbocyclic rings or by carbon chains interrupted by carbocyclic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
- C07D295/08—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms
- C07D295/096—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms separated by carbocyclic rings or by carbon chains interrupted by carbocyclic rings
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Pyridine Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US440431A US3919230A (en) | 1974-02-07 | 1974-02-07 | {62 -Naphthylmethyl piperazinyl derivatives |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| IE40593L IE40593L (en) | 1975-08-07 |
| IE40593B1 true IE40593B1 (en) | 1979-07-04 |
Family
ID=23748733
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IE254/75A IE40593B1 (en) | 1974-02-07 | 1975-02-07 | Novel piperazine derivatives and compositions containing them for treating parkinson's disease |
Country Status (16)
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4130646A (en) * | 1975-07-25 | 1978-12-19 | E. R. Squibb & Sons, Inc. | 1,2,3,4-Tetrahydro-2-((4-(phenyl)-1-piperazinyl)methyl)-1-naphthalenols and derivatives and analogs thereof |
| JPS52133993A (en) * | 1976-04-29 | 1977-11-09 | Takeda Chem Ind Ltd | 1.2-dihydronaphthalene derivatives and method of preparing the same |
| US4367335A (en) * | 1981-08-03 | 1983-01-04 | Mead Johnson & Company | Thiazolidinylalkylene piperazine derivatives |
| US4620006A (en) * | 1982-08-11 | 1986-10-28 | Eastman Kodak Company | Acid salts of 1-(cyanoalkyl)-4-guanylpiperazines |
| WO2000051547A2 (en) * | 1999-03-03 | 2000-09-08 | Merck & Co., Inc. | Inhibitors of prenyl-protein transferase |
| CN107652156B (zh) * | 2017-11-18 | 2023-11-10 | 辽宁科技学院 | 一种β-甲基萘的结晶方法和装置 |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| NL127996C (enrdf_load_stackoverflow) * | 1963-11-19 |
-
1974
- 1974-02-07 US US440431A patent/US3919230A/en not_active Expired - Lifetime
-
1975
- 1975-01-09 ZA ZA00750160A patent/ZA75160B/xx unknown
- 1975-02-03 CA CA219,288A patent/CA1042434A/en not_active Expired
- 1975-02-03 GB GB453675A patent/GB1449802A/en not_active Expired
- 1975-02-03 JP JP50014791A patent/JPS50108278A/ja active Pending
- 1975-02-03 AU AU77840/75A patent/AU501049B2/en not_active Expired
- 1975-02-04 CH CH132675A patent/CH616678A5/de not_active IP Right Cessation
- 1975-02-04 ES ES434433A patent/ES434433A1/es not_active Expired
- 1975-02-04 BE BE153056A patent/BE825178A/xx not_active IP Right Cessation
- 1975-02-04 IL IL46568A patent/IL46568A/xx unknown
- 1975-02-05 NL NL7501362A patent/NL7501362A/xx not_active Application Discontinuation
- 1975-02-05 FR FR7503627A patent/FR2260353B1/fr not_active Expired
- 1975-02-06 DE DE19752505002 patent/DE2505002A1/de not_active Ceased
- 1975-02-06 LU LU71803A patent/LU71803A1/xx unknown
- 1975-02-07 IE IE254/75A patent/IE40593B1/xx unknown
- 1975-02-07 HU HU75SI00001455A patent/HU171352B/hu unknown
Also Published As
| Publication number | Publication date |
|---|---|
| AU501049B2 (en) | 1979-06-07 |
| JPS50108278A (enrdf_load_stackoverflow) | 1975-08-26 |
| GB1449802A (en) | 1976-09-15 |
| ES434433A1 (es) | 1976-11-16 |
| IL46568A (en) | 1979-01-31 |
| CA1042434A (en) | 1978-11-14 |
| IE40593L (en) | 1975-08-07 |
| HU171352B (hu) | 1977-12-28 |
| AU7784075A (en) | 1976-08-05 |
| DE2505002A1 (de) | 1975-08-14 |
| FR2260353A1 (enrdf_load_stackoverflow) | 1975-09-05 |
| IL46568A0 (en) | 1975-04-25 |
| CH616678A5 (enrdf_load_stackoverflow) | 1980-04-15 |
| US3919230A (en) | 1975-11-11 |
| LU71803A1 (enrdf_load_stackoverflow) | 1975-06-24 |
| FR2260353B1 (enrdf_load_stackoverflow) | 1980-01-04 |
| NL7501362A (nl) | 1975-08-11 |
| BE825178A (fr) | 1975-08-04 |
| ZA75160B (en) | 1976-01-28 |
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