IE40067L - 4-oxo-2-imidazolidinylideneureas - Google Patents
4-oxo-2-imidazolidinylideneureasInfo
- Publication number
- IE40067L IE40067L IE742146A IE214674A IE40067L IE 40067 L IE40067 L IE 40067L IE 742146 A IE742146 A IE 742146A IE 214674 A IE214674 A IE 214674A IE 40067 L IE40067 L IE 40067L
- Authority
- IE
- Ireland
- Prior art keywords
- denotes
- hydrogen atom
- radical
- compounds
- aryl
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/66—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D233/88—Nitrogen atoms, e.g. allantoin
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
Novel 4-oxo-2-imidazolidinylidene-ureas of the formula <IMAGE> wherein R1 denotes a hydrogen atom or a lower alkyl radical, R2 denotes a hydrogen atom or a lower alkyl radical, R3 denotes a hydrogen atom or an aryl radical, R4 denotes a hydrogen atom, an aryl radical or an arylalkyl radical and Ar denotes an aryl radical, with the exception of compounds in which R3 and R4 represent 2,6-disubstituted aryl radicals, are prepared. These compounds are obtained by reacting a correspondingly substituted 2-iminoimidazolidin-4-one with an arylisocyanate in an inert aprotic organic solvent. The novel compounds exert an inhibiting action on the secretion of gastric juices and a damping (suppressing) action on the central nervous system.
[GB1479909A]
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US40802273A | 1973-10-19 | 1973-10-19 | |
| US50879574A | 1974-09-23 | 1974-09-23 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| IE40067L true IE40067L (en) | 1975-04-19 |
| IE40067B1 IE40067B1 (en) | 1979-02-28 |
Family
ID=27020109
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IE2146/74A IE40067B1 (en) | 1973-10-19 | 1974-10-18 | 4-oxo-2-imidazolidinylideneureas |
Country Status (22)
| Country | Link |
|---|---|
| JP (1) | JPS5077367A (en) |
| AR (1) | AR210320A1 (en) |
| AT (1) | AT348536B (en) |
| BE (1) | BE821099A (en) |
| CA (1) | CA1043339A (en) |
| CH (1) | CH614198A5 (en) |
| DD (1) | DD114079A5 (en) |
| DE (1) | DE2448869A1 (en) |
| DK (1) | DK548874A (en) |
| ES (1) | ES431153A1 (en) |
| FI (1) | FI59993C (en) |
| FR (1) | FR2248042B1 (en) |
| GB (1) | GB1479909A (en) |
| HU (1) | HU170857B (en) |
| IE (1) | IE40067B1 (en) |
| IL (1) | IL45865A (en) |
| IN (1) | IN139447B (en) |
| NL (1) | NL7413718A (en) |
| NO (1) | NO141162C (en) |
| RO (1) | RO64926A (en) |
| SE (1) | SE414173B (en) |
| YU (1) | YU36932B (en) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FI800559A (en) * | 1979-03-14 | 1980-09-15 | Hoffmann La Roche | URINAEMNEDERIVAT |
| US4265900A (en) * | 1979-10-29 | 1981-05-05 | Mcneilab, Inc. | N-Aryl-N'-imidazol-2-ylureas |
| JP5020638B2 (en) * | 2003-12-15 | 2012-09-05 | シェーリング コーポレイション | Heterocyclic aspartyl protease inhibitors |
| JP6471100B2 (en) * | 2013-02-12 | 2019-02-13 | バック・インスティテュート・フォー・リサーチ・オン・エイジング | Hydantoins that regulate BACE-mediated APP processing |
-
1974
- 1974-10-14 DE DE19742448869 patent/DE2448869A1/en not_active Withdrawn
- 1974-10-15 BE BE149558A patent/BE821099A/en unknown
- 1974-10-15 SE SE7412959A patent/SE414173B/en unknown
- 1974-10-16 AR AR256117A patent/AR210320A1/en active
- 1974-10-17 IL IL45865A patent/IL45865A/en unknown
- 1974-10-17 RO RO197480253A patent/RO64926A/en unknown
- 1974-10-17 CH CH1395174A patent/CH614198A5/en not_active IP Right Cessation
- 1974-10-18 ES ES431153A patent/ES431153A1/en not_active Expired
- 1974-10-18 GB GB45246/74A patent/GB1479909A/en not_active Expired
- 1974-10-18 YU YU2797/74A patent/YU36932B/en unknown
- 1974-10-18 IE IE2146/74A patent/IE40067B1/en unknown
- 1974-10-18 AT AT840974A patent/AT348536B/en not_active IP Right Cessation
- 1974-10-18 FR FR7435155A patent/FR2248042B1/fr not_active Expired
- 1974-10-18 HU HU74ME00001786A patent/HU170857B/en unknown
- 1974-10-18 CA CA211,775A patent/CA1043339A/en not_active Expired
- 1974-10-18 FI FI3065/74A patent/FI59993C/en active
- 1974-10-18 NL NL7413718A patent/NL7413718A/en not_active Application Discontinuation
- 1974-10-18 DK DK548874A patent/DK548874A/da not_active Application Discontinuation
- 1974-10-18 JP JP49119494A patent/JPS5077367A/ja active Pending
- 1974-10-18 NO NO743771A patent/NO141162C/en unknown
- 1974-10-21 DD DD181808A patent/DD114079A5/xx unknown
- 1974-11-07 IN IN2451/CAL/74A patent/IN139447B/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| DD114079A5 (en) | 1975-07-12 |
| IL45865A (en) | 1978-01-31 |
| FI59993C (en) | 1981-11-10 |
| FR2248042B1 (en) | 1978-07-21 |
| JPS5077367A (en) | 1975-06-24 |
| NO141162B (en) | 1979-10-15 |
| HU170857B (en) | 1977-09-28 |
| ATA840974A (en) | 1978-07-15 |
| CH614198A5 (en) | 1979-11-15 |
| DE2448869A1 (en) | 1975-09-04 |
| IL45865A0 (en) | 1975-02-10 |
| DK548874A (en) | 1975-07-07 |
| RO64926A (en) | 1980-01-15 |
| AT348536B (en) | 1979-02-26 |
| CA1043339A (en) | 1978-11-28 |
| NO743771L (en) | 1975-05-20 |
| AU7443874A (en) | 1976-04-29 |
| SE7412959L (en) | 1975-04-21 |
| FR2248042A1 (en) | 1975-05-16 |
| IE40067B1 (en) | 1979-02-28 |
| IN139447B (en) | 1976-06-19 |
| FI306574A (en) | 1975-04-20 |
| YU36932B (en) | 1984-08-31 |
| SE414173B (en) | 1980-07-14 |
| GB1479909A (en) | 1977-07-13 |
| YU279774A (en) | 1982-06-18 |
| FI59993B (en) | 1981-07-31 |
| NO141162C (en) | 1980-01-23 |
| BE821099A (en) | 1975-04-15 |
| AR210320A1 (en) | 1977-07-29 |
| NL7413718A (en) | 1975-04-22 |
| ES431153A1 (en) | 1977-02-01 |
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