IE39227B1 - 8-aza-11,12 secoprostaglandins - Google Patents

8-aza-11,12 secoprostaglandins

Info

Publication number
IE39227B1
IE39227B1 IE843/74A IE84374A IE39227B1 IE 39227 B1 IE39227 B1 IE 39227B1 IE 843/74 A IE843/74 A IE 843/74A IE 84374 A IE84374 A IE 84374A IE 39227 B1 IE39227 B1 IE 39227B1
Authority
IE
Ireland
Prior art keywords
ethyl
reacting
heptanoate
alkyl
prepared
Prior art date
Application number
IE843/74A
Other languages
English (en)
Other versions
IE39227L (en
Original Assignee
Merck & Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck & Co Inc filed Critical Merck & Co Inc
Publication of IE39227L publication Critical patent/IE39227L/xx
Publication of IE39227B1 publication Critical patent/IE39227B1/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D309/00Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings
    • C07D309/02Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
    • C07D309/08Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D309/10Oxygen atoms
    • C07D309/12Oxygen atoms only hydrogen atoms and one oxygen atom directly attached to ring carbon atoms, e.g. tetrahydropyranyl ethers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00Drugs for disorders of the urinary system
    • A61P13/02Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00Drugs for genital or sexual disorders; Contraceptives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C29/00Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring
    • C07C29/132Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring by reduction of an oxygen containing functional group
    • C07C29/136Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring by reduction of an oxygen containing functional group of >C=O containing groups, e.g. —COOH
    • C07C29/147Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring by reduction of an oxygen containing functional group of >C=O containing groups, e.g. —COOH of carboxylic acids or derivatives thereof
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C53/00Saturated compounds having only one carboxyl group bound to an acyclic carbon atom or hydrogen
    • C07C53/15Saturated compounds having only one carboxyl group bound to an acyclic carbon atom or hydrogen containing halogen
    • C07C53/19Acids containing three or more carbon atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Urology & Nephrology (AREA)
  • Endocrinology (AREA)
  • Reproductive Health (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pyrane Compounds (AREA)
IE843/74A 1973-04-25 1974-04-19 8-aza-11,12 secoprostaglandins IE39227B1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US35427373A 1973-04-25 1973-04-25
US41834173A 1973-11-23 1973-11-23

Publications (2)

Publication Number Publication Date
IE39227L IE39227L (en) 1974-10-25
IE39227B1 true IE39227B1 (en) 1978-08-30

Family

ID=26998324

Family Applications (1)

Application Number Title Priority Date Filing Date
IE843/74A IE39227B1 (en) 1973-04-25 1974-04-19 8-aza-11,12 secoprostaglandins

Country Status (14)

Country Link
JP (1) JPS5013331A (fr)
AR (1) AR211319A1 (fr)
BE (1) BE814089A (fr)
CA (1) CA1044701A (fr)
CH (1) CH605714A5 (fr)
DE (1) DE2419860A1 (fr)
ES (1) ES425591A1 (fr)
FR (1) FR2226995B1 (fr)
GB (1) GB1429092A (fr)
IE (1) IE39227B1 (fr)
IL (1) IL44636A (fr)
NL (1) NL7404839A (fr)
NO (1) NO139438C (fr)
SE (1) SE410185B (fr)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3991087A (en) 1973-12-13 1976-11-09 Merck & Co., Inc. 8-Halo-11,12-secoprostaglandins
AT351182B (de) * 1974-06-25 1979-07-10 Merck & Co Inc Verfahren zur herstellung von neuen 9-thia-, 9-oxothia- und 9-dioxothia- 11,12-secoprosta- glandinen
US4018802A (en) * 1975-04-09 1977-04-19 Merck & Co., Inc. 9-Thia- and oxothia- and 9-dioxothia-11,12-seco-prostaglandins and processes
US4128564A (en) * 1976-03-22 1978-12-05 Merck & Co., Inc. 9-Thia- and oxothia- and 9-dioxothia-11,12-seco-prostaglandins

Also Published As

Publication number Publication date
FR2226995B1 (fr) 1977-01-28
GB1429092A (en) 1976-03-24
IL44636A0 (en) 1974-06-30
BE814089A (fr) 1974-10-24
CH605714A5 (fr) 1978-10-13
FR2226995A1 (fr) 1974-11-22
NL7404839A (fr) 1974-10-29
AU6797374A (en) 1975-10-23
IE39227L (en) 1974-10-25
NO741309L (no) 1974-10-28
IL44636A (en) 1977-06-30
CA1044701A (fr) 1978-12-19
ES425591A1 (es) 1976-11-01
NO139438C (no) 1979-03-14
NO139438B (no) 1978-12-04
JPS5013331A (fr) 1975-02-12
DE2419860A1 (de) 1974-11-07
SE410185B (sv) 1979-10-01
AR211319A1 (es) 1977-11-20

Similar Documents

Publication Publication Date Title
GB1506808A (en) N-(alpha-phenylbenzylidene)aminoalkanoic acid derivatives methods for their preparation and compositions containing them
GB1432576A (en) Substituted phenylacetic acids
GB1477280A (en) 11,12-secoprostaglandins
IE39227L (en) 8-aza-11, 12-secoprostaglandins
GB1472467A (en) Thiohydantoins
GB1355147A (en) Oxoprostanoic acid derivatives
GB1427090A (en) Fused indanone derivatives
GB1410853A (en) Pharmaceutically useful prostaglandin derivatives
GB1252329A (fr)
GB1251750A (fr)
IE40447B1 (en) Disubstituted azabicycloalkanes, a process for their prepation and pharmaceutical compositions containing them
GB1409648A (en) Substituted pyrrolidinemethanol compounds and pharmaceutical compositions thereof
GB1168108A (en) Amide Derivatives of 1-Piperazine Acetic Acid and Process for their Preparation
IE39576B1 (en) Derivatives of 3-(p-chlorobenzoyl)-2-methyl-phenylacetic acid
GB1314952A (en) 3,4,5-trialkoxy-benzoic acid derivatives and their uses
GB1202010A (en) Prostaglandins and the manufacture thereof
GB1274453A (en) Bronchodilatory compositions and nebulizers containing them
GB1469430A (en) Daunomycin derivatives
GB1203538A (en) Cubane derivatives
GB1429599A (en) 8-aza-11,12-secoprostaglandins
GB1347977A (en) Tricyclic derivatives of aliphatic omega-amino alcohols and a process for preparing them
GB1473212A (en) Thiazolylmethyl acetic acid derivatives methods for their preparation and compositions containing them
GB1445628A (en) Prostaglandin derivatives
GB1513280A (en) Therapeutic pyrazole derivatives
GB1460811A (en) Bis-benzamido-benzoic acid derivatives