IE38930B1 - Production of 2,5-disubstituted benzamides - Google Patents
Production of 2,5-disubstituted benzamidesInfo
- Publication number
- IE38930B1 IE38930B1 IE39174A IE39174A IE38930B1 IE 38930 B1 IE38930 B1 IE 38930B1 IE 39174 A IE39174 A IE 39174A IE 39174 A IE39174 A IE 39174A IE 38930 B1 IE38930 B1 IE 38930B1
- Authority
- IE
- Ireland
- Prior art keywords
- alkenyl
- alkyl
- formula
- disubstituted
- mono
- Prior art date
Links
- 229940054066 benzamide antipsychotics Drugs 0.000 title abstract 2
- 150000003936 benzamides Chemical class 0.000 title abstract 2
- 125000003342 alkenyl group Chemical group 0.000 abstract 3
- 125000000217 alkyl group Chemical group 0.000 abstract 3
- -1 2,5-disubstituted benzoic acid Chemical class 0.000 abstract 2
- NGNBDVOYPDDBFK-UHFFFAOYSA-N 2-[2,4-di(pentan-2-yl)phenoxy]acetyl chloride Chemical compound CCCC(C)C1=CC=C(OCC(Cl)=O)C(C(C)CCC)=C1 NGNBDVOYPDDBFK-UHFFFAOYSA-N 0.000 abstract 2
- 125000003282 alkyl amino group Chemical group 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 125000004663 dialkyl amino group Chemical group 0.000 abstract 1
- 125000001664 diethylamino group Chemical group [H]C([H])([H])C([H])([H])N(*)C([H])([H])C([H])([H])[H] 0.000 abstract 1
- 125000000623 heterocyclic group Chemical group 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 229920006395 saturated elastomer Polymers 0.000 abstract 1
- JSYRZFVPILRZHG-UHFFFAOYSA-M triphenyl(trichloromethyl)phosphanium;chloride Chemical compound [Cl-].C=1C=CC=CC=1[P+](C=1C=CC=CC=1)(C(Cl)(Cl)Cl)C1=CC=CC=C1 JSYRZFVPILRZHG-UHFFFAOYSA-M 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/04—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D207/08—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon radicals, substituted by hetero atoms, attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C311/00—Amides of sulfonic acids, i.e. compounds having singly-bound oxygen atoms of sulfo groups replaced by nitrogen atoms, not being part of nitro or nitroso groups
- C07C311/30—Sulfonamides, the carbon skeleton of the acid part being further substituted by singly-bound nitrogen atoms, not being part of nitro or nitroso groups
- C07C311/37—Sulfonamides, the carbon skeleton of the acid part being further substituted by singly-bound nitrogen atoms, not being part of nitro or nitroso groups having the sulfur atom of at least one of the sulfonamide groups bound to a carbon atom of a six-membered aromatic ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D227/00—Heterocyclic compounds containing rings having one nitrogen atom as the only ring hetero atom, according to more than one of groups C07D203/00 - C07D225/00
- C07D227/02—Heterocyclic compounds containing rings having one nitrogen atom as the only ring hetero atom, according to more than one of groups C07D203/00 - C07D225/00 with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D227/04—Heterocyclic compounds containing rings having one nitrogen atom as the only ring hetero atom, according to more than one of groups C07D203/00 - C07D225/00 with only hydrogen or carbon atoms directly attached to the ring nitrogen atom with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/28—Phosphorus compounds with one or more P—C bonds
- C07F9/54—Quaternary phosphonium compounds
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Molecular Biology (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pyrrole Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
1420896 Process for 2,5-disubstituted benzamides SOC D'ETUDES SCIENTIFIQUES ET INDUSTRIELLES DE L'ILE - DEFRANCE 26 Feb 1974 [2 March 1973] 8668/74 Headings C2C and C2P Compounds of Formula (I) are made by reacting a 2,5-disubstituted benzoic acid with triphenyltrichloromethylphosphonium chloride (obtained by treating Ph 3 P with CCl 4 ) to give compounds of Formula (III); (III) is then heated to give the acid chloride (IV) which is thereafter reacted with H 2 N(CH 2 ) n A (I may, if desired, be converted into salts; A is mono- or di-C 1-5 alkylamino, or a heterocyclic saturated ring containing N, O and/or S, B is C 1-5 alkyl or alkenyl, n is 1 or 2 and X is NH 2 , mono- or dialkylamino, alkenyl or alkyl). A is, e.g. diethylamino or a group of Formula (II) where R is C 1-5 alkyl or alkenyl and m is 1 to 3, especially a 1-ethyl-2-pyrrolidyl group.
[GB1420896A]
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR7307645A FR2219942B1 (en) | 1973-03-02 | 1973-03-02 |
Publications (2)
Publication Number | Publication Date |
---|---|
IE38930L IE38930L (en) | 1974-09-02 |
IE38930B1 true IE38930B1 (en) | 1978-07-05 |
Family
ID=9115740
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IE39174A IE38930B1 (en) | 1973-03-02 | 1974-02-26 | Production of 2,5-disubstituted benzamides |
Country Status (9)
Country | Link |
---|---|
JP (1) | JPS5726509B2 (en) |
AR (1) | AR202295A1 (en) |
AT (1) | AT331222B (en) |
CA (1) | CA1015364A (en) |
DE (1) | DE2409387A1 (en) |
ES (1) | ES423630A1 (en) |
FR (1) | FR2219942B1 (en) |
GB (1) | GB1420896A (en) |
IE (1) | IE38930B1 (en) |
Families Citing this family (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2305176A1 (en) * | 1975-03-28 | 1976-10-22 | Ile De France | NEW DRUG BASED ON N- (DIETHYLAMINOETHYL) 2-METHOXY-5-METHYL-SULFONYL BENZAMIDE |
JPS6329764Y2 (en) * | 1980-12-15 | 1988-08-10 |
Family Cites Families (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB994023A (en) * | 1961-07-25 | 1965-06-02 | Ile De France | Substituted n-(tertiary amino alkyl)benzamides |
-
1973
- 1973-03-02 FR FR7307645A patent/FR2219942B1/fr not_active Expired
-
1974
- 1974-02-25 CA CA193,355A patent/CA1015364A/en not_active Expired
- 1974-02-25 JP JP2223874A patent/JPS5726509B2/ja not_active Expired
- 1974-02-26 GB GB860074A patent/GB1420896A/en not_active Expired
- 1974-02-26 IE IE39174A patent/IE38930B1/en unknown
- 1974-02-26 ES ES423630A patent/ES423630A1/en not_active Expired
- 1974-02-27 AT AT159174A patent/AT331222B/en not_active IP Right Cessation
- 1974-02-27 AR AR25252374A patent/AR202295A1/en active
- 1974-02-27 DE DE19742409387 patent/DE2409387A1/en active Pending
Also Published As
Publication number | Publication date |
---|---|
FR2219942A1 (en) | 1974-09-27 |
IE38930L (en) | 1974-09-02 |
AR202295A1 (en) | 1975-05-30 |
JPS49134651A (en) | 1974-12-25 |
DE2409387A1 (en) | 1974-09-05 |
ATA159174A (en) | 1975-11-15 |
CA1015364A (en) | 1977-08-09 |
AT331222B (en) | 1976-08-10 |
FR2219942B1 (en) | 1977-12-30 |
JPS5726509B2 (en) | 1982-06-04 |
GB1420896A (en) | 1976-01-14 |
ES423630A1 (en) | 1976-05-01 |
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