IE38552B1 - New imidazo 2,1-b thiazole derivatives - Google Patents
New imidazo 2,1-b thiazole derivativesInfo
- Publication number
- IE38552B1 IE38552B1 IE2155/73A IE215573A IE38552B1 IE 38552 B1 IE38552 B1 IE 38552B1 IE 2155/73 A IE2155/73 A IE 2155/73A IE 215573 A IE215573 A IE 215573A IE 38552 B1 IE38552 B1 IE 38552B1
- Authority
- IE
- Ireland
- Prior art keywords
- thiazole derivatives
- substituted
- alkyl
- imidazo
- carrying
- Prior art date
Links
- 150000007979 thiazole derivatives Chemical class 0.000 title 1
- 125000000217 alkyl group Chemical group 0.000 abstract 2
- 125000004105 2-pyridyl group Chemical group N1=C([*])C([H])=C([H])C([H])=C1[H] 0.000 abstract 1
- 125000003349 3-pyridyl group Chemical group N1=C([H])C([*])=C([H])C([H])=C1[H] 0.000 abstract 1
- CIUQDSCDWFSTQR-UHFFFAOYSA-N [C]1=CC=CC=C1 Chemical compound [C]1=CC=CC=C1 CIUQDSCDWFSTQR-UHFFFAOYSA-N 0.000 abstract 1
- 125000003545 alkoxy group Chemical group 0.000 abstract 1
- 125000004414 alkyl thio group Chemical group 0.000 abstract 1
- 230000001430 anti-depressive effect Effects 0.000 abstract 1
- 239000000935 antidepressant agent Substances 0.000 abstract 1
- 229940005513 antidepressants Drugs 0.000 abstract 1
- 125000004429 atom Chemical group 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 125000004093 cyano group Chemical group *C#N 0.000 abstract 1
- 125000004663 dialkyl amino group Chemical group 0.000 abstract 1
- -1 dialkylsulphamoyl Chemical group 0.000 abstract 1
- 125000005843 halogen group Chemical group 0.000 abstract 1
- UFBBWLWUIISIPW-UHFFFAOYSA-N imidazo[2,1-b][1,3]thiazole Chemical class C1=CSC2=NC=CN21 UFBBWLWUIISIPW-UHFFFAOYSA-N 0.000 abstract 1
- 125000000449 nitro group Chemical group [O-][N+](*)=O 0.000 abstract 1
- 230000000144 pharmacologic effect Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D213/28—Radicals substituted by singly-bound oxygen or sulphur atoms
- C07D213/30—Oxygen atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/425—Thiazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/26—Psychostimulants, e.g. nicotine, cocaine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
- C07C45/61—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups
- C07C45/63—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by introduction of halogen; by substitution of halogen atoms by other halogen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D213/36—Radicals substituted by singly-bound nitrogen atoms
- C07D213/38—Radicals substituted by singly-bound nitrogen atoms having only hydrogen or hydrocarbon radicals attached to the substituent nitrogen atom
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/04—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
- C07D233/28—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D233/30—Oxygen or sulfur atoms
- C07D233/32—One oxygen atom
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D303/00—Compounds containing three-membered rings having one oxygen atom as the only ring hetero atom
- C07D303/02—Compounds containing oxirane rings
- C07D303/08—Compounds containing oxirane rings with hydrocarbon radicals, substituted by halogen atoms, nitro radicals or nitroso radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D303/00—Compounds containing three-membered rings having one oxygen atom as the only ring hetero atom
- C07D303/02—Compounds containing oxirane rings
- C07D303/12—Compounds containing oxirane rings with hydrocarbon radicals, substituted by singly or doubly bound oxygen atoms
- C07D303/18—Compounds containing oxirane rings with hydrocarbon radicals, substituted by singly or doubly bound oxygen atoms by etherified hydroxyl radicals
- C07D303/20—Ethers with hydroxy compounds containing no oxirane rings
- C07D303/22—Ethers with hydroxy compounds containing no oxirane rings with monohydroxy compounds
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D303/00—Compounds containing three-membered rings having one oxygen atom as the only ring hetero atom
- C07D303/02—Compounds containing oxirane rings
- C07D303/34—Compounds containing oxirane rings with hydrocarbon radicals, substituted by sulphur, selenium or tellurium atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
- C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
- C07D513/04—Ortho-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Epidemiology (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Psychiatry (AREA)
- Neurosurgery (AREA)
- Pain & Pain Management (AREA)
- Child & Adolescent Psychology (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR7242580A FR2207708A1 (en) | 1972-11-30 | 1972-11-30 | 2-Aryl-2,3,5,6-tetrahydroimidazo(2,1-b)thiazoles - with antidepressant, psychoenergising and anorectic activity |
| FR7335158A FR2245348A1 (en) | 1973-10-02 | 1973-10-02 | 2-Aryl-2,3,5,6-tetrahydroimidazo(2,1-b)thiazoles - with antidepressant, psychoenergising and anorectic activity |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| IE38552L IE38552L (en) | 1974-05-30 |
| IE38552B1 true IE38552B1 (en) | 1978-04-12 |
Family
ID=26217429
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IE2155/73A IE38552B1 (en) | 1972-11-30 | 1973-11-28 | New imidazo 2,1-b thiazole derivatives |
Country Status (20)
| Country | Link |
|---|---|
| US (1) | US4005212A (OSRAM) |
| JP (1) | JPS5314077B2 (OSRAM) |
| AR (1) | AR203186A1 (OSRAM) |
| AT (1) | AT329554B (OSRAM) |
| BE (1) | BE808008A (OSRAM) |
| CA (1) | CA1002955A (OSRAM) |
| CH (1) | CH579577A5 (OSRAM) |
| DD (1) | DD107697A5 (OSRAM) |
| DE (1) | DE2359864A1 (OSRAM) |
| DK (1) | DK136823B (OSRAM) |
| ES (1) | ES421011A1 (OSRAM) |
| GB (1) | GB1404708A (OSRAM) |
| HU (1) | HU167368B (OSRAM) |
| IE (1) | IE38552B1 (OSRAM) |
| IL (1) | IL43723A (OSRAM) |
| LU (1) | LU68887A1 (OSRAM) |
| NL (1) | NL7316016A (OSRAM) |
| OA (1) | OA04567A (OSRAM) |
| SE (1) | SE399894B (OSRAM) |
| SU (1) | SU518133A3 (OSRAM) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4179460A (en) * | 1977-07-06 | 1979-12-18 | Dso "Pharmachim" | Derivatives of R,S-[X2-(2-hydroxyethylamino)-1-phenyl]-ethylamine, and process |
| US4370482A (en) | 1978-02-15 | 1983-01-25 | American Cyanamid Co. | Synthesis of tetramisole, levamisole and their derivatives |
| US4620009A (en) * | 1980-03-17 | 1986-10-28 | Cyanamid Agricultural De Puerto Rico, Inc. | Synthesis of intermediates for tetramisole, levamisole and their derivatives |
| ZA827736B (en) * | 1981-11-25 | 1983-08-31 | Pfizer | Bicyclic imidazole and imidazolines as ectoparasiticides and anthelmintics |
| EP0103830A3 (de) * | 1982-09-22 | 1985-07-31 | Bayer Ag | Wachstumsfördernde Phenylethylamin-Derivate |
| US5516647A (en) * | 1993-11-05 | 1996-05-14 | Abbott Laboratories | Compounds useful as alkaline phosphatase inhibitors and therapeutic agents |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU409983B2 (en) * | 1965-07-19 | 1970-12-31 | Imperial Chemical Industries Of Australia New Zealand Limited | Process for the manufacture of thia zolidines and thiazolidines produced thereby |
-
1973
- 1973-11-08 OA OA55057A patent/OA04567A/xx unknown
- 1973-11-22 NL NL7316016A patent/NL7316016A/xx not_active Application Discontinuation
- 1973-11-28 DD DD174937*A patent/DD107697A5/xx unknown
- 1973-11-28 HU HURO761A patent/HU167368B/hu unknown
- 1973-11-28 JP JP13279973A patent/JPS5314077B2/ja not_active Expired
- 1973-11-28 IE IE2155/73A patent/IE38552B1/xx unknown
- 1973-11-29 SE SE7316177A patent/SE399894B/xx unknown
- 1973-11-29 IL IL43723A patent/IL43723A/xx unknown
- 1973-11-29 LU LU68887A patent/LU68887A1/xx unknown
- 1973-11-29 CH CH1676473A patent/CH579577A5/xx not_active IP Right Cessation
- 1973-11-29 CA CA186,961A patent/CA1002955A/fr not_active Expired
- 1973-11-29 DK DK645473AA patent/DK136823B/da unknown
- 1973-11-29 BE BE138342A patent/BE808008A/xx unknown
- 1973-11-29 GB GB5550473A patent/GB1404708A/en not_active Expired
- 1973-11-29 SU SU1973176A patent/SU518133A3/ru active
- 1973-11-30 AR AR251306A patent/AR203186A1/es active
- 1973-11-30 ES ES421011A patent/ES421011A1/es not_active Expired
- 1973-11-30 DE DE2359864A patent/DE2359864A1/de active Pending
- 1973-11-30 AT AT1005173A patent/AT329554B/de not_active IP Right Cessation
-
1975
- 1975-05-12 US US05/576,297 patent/US4005212A/en not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| SU518133A3 (ru) | 1976-06-15 |
| GB1404708A (en) | 1975-09-03 |
| DK136823C (OSRAM) | 1978-05-08 |
| AU6300973A (en) | 1975-05-29 |
| SE399894B (sv) | 1978-03-06 |
| AT329554B (de) | 1976-05-25 |
| JPS5314077B2 (OSRAM) | 1978-05-15 |
| CH579577A5 (OSRAM) | 1976-09-15 |
| IL43723A (en) | 1976-07-30 |
| DE2359864A1 (de) | 1974-06-06 |
| IL43723A0 (en) | 1974-03-14 |
| LU68887A1 (OSRAM) | 1974-07-05 |
| JPS4993390A (OSRAM) | 1974-09-05 |
| BE808008A (fr) | 1974-05-29 |
| HU167368B (OSRAM) | 1975-09-27 |
| OA04567A (fr) | 1980-05-31 |
| NL7316016A (OSRAM) | 1974-06-04 |
| US4005212A (en) | 1977-01-25 |
| CA1002955A (fr) | 1977-01-04 |
| DK136823B (da) | 1977-11-28 |
| ES421011A1 (es) | 1976-06-16 |
| AR203186A1 (es) | 1975-08-22 |
| ATA1005173A (de) | 1975-08-15 |
| DD107697A5 (OSRAM) | 1974-08-12 |
| IE38552L (en) | 1974-05-30 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| DE59108494D1 (de) | 1-H-3-Aryl-pyrrolidin-2,4-dion-Derivate | |
| NO144850C (no) | Analogifremgangsmaate til fremstilling av immunpotenserende glukosaminderivater. | |
| AU5848480A (en) | 2-(pyrimidinyl-amino)-1,3-diaza-2-cycloalkene derivatives | |
| DK140014B (da) | Fremgangsmåde til fremstilling af 3,4-dihydro-2-alkyl-4-oxo-2H-1,2-benzothiazin-3-carboxamid-1,1-dioxid-forbindelser. | |
| DK13082A (da) | Analogifremgangsmaade til fremstilling af n-(2-pyridyl)-2-methyl-4-hydroxy-2h-1,2-benzothiazin-3-carboxamid-1,1-dioxid-derivater | |
| NO145723C (no) | Derivater av cumylfenol til anvendelse som additiver i plast | |
| IE38552L (en) | IMIDAZO [2,1-b] THIAZOLES | |
| FI792032A7 (fi) | Menetelmä östraanisarjan 14,15- metyleenijohdannaisten valmistamiseksi. | |
| NO156086C (no) | Analogifremgangsmaate for fremstilling av substituerte heterocykliske fenoksyaminer. | |
| NL7700381A (nl) | Werkwijze voor het bereiden van thiazolidine- derivaten. | |
| IT8323022A0 (it) | 2-sostituiti e relativo antibiotici di carbapenem derivati procedimento di preparazione. | |
| NO147716C (no) | Analogifremgangsmaate for fremstilling av antibakterielle erytromycylaminderivater. | |
| FI840153L (fi) | 5-(4-vinyl-eller 4-etynylbensoyl)-1,2- dihydro-3h-pyrrolo-/1,2-a/-pyrroli-1-karboxylsyror och deras derivat. | |
| NL7608989A (nl) | Dihydro-1,4 pyridinederivaten. | |
| NL7708543A (nl) | Werkwijze voor het bereiden van 5-amino-1,2,3-thia- diazool en derivaten daarvan. | |
| NO802453L (no) | Heterocykliske forbindelser. | |
| NL7706505A (nl) | Werkwijze ter bereiding van 5-(kwaternair alkyl) resorcinolderivaten en van tussenprodukten daar- voor. | |
| DK133676B (da) | Analogifremgangsmåde til fremstilling af 6-(beta-amino-alkoxy)-4,7-dimethoxydihydrobenzofuranderivater. | |
| NO911845L (no) | Analogifremgangsmaate for fremstilling av nye, terapeutiskaktive trisykliske forbindelser. | |
| IE37851B1 (en) | 3-alkyl-4-sulphamoyl-aniline derivatives | |
| NL7408808A (nl) | Wanddeel voor het samenstellen van wooneenheden, alsmede werkwijze voor het verplaatsen en be- handelen van dergelijke wooneenheden. | |
| IT7924171A0 (it) | Imidazoliletossi-derivati di pirazol-aperta parentesi quadra 3,4-b chiusa parentesi quadra-piridin-5-metanoli. | |
| NL7411587A (nl) | Fotochrome verbindingen alsmede werkwijze voor het bereiden daarvan. | |
| IE790090L (en) | 1-hydroxymethylimidazoles | |
| FI820923A7 (fi) | Menetelmä 2-amino-5-(o-sulfamidofenyyli)-1,3,4- tiadiatsolijohdannaisten valmistamiseksi. |