IE38141B1 - New 3,4-dihydropyridones their production and their medicinal use - Google Patents

New 3,4-dihydropyridones their production and their medicinal use

Info

Publication number
IE38141B1
IE38141B1 IE1524/73A IE152473A IE38141B1 IE 38141 B1 IE38141 B1 IE 38141B1 IE 1524/73 A IE1524/73 A IE 1524/73A IE 152473 A IE152473 A IE 152473A IE 38141 B1 IE38141 B1 IE 38141B1
Authority
IE
Ireland
Prior art keywords
alkyl
straight
hydrocarbon
formula
branched
Prior art date
Application number
IE1524/73A
Other languages
English (en)
Other versions
IE38141L (en
Original Assignee
Bayer Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer Ag filed Critical Bayer Ag
Publication of IE38141L publication Critical patent/IE38141L/xx
Publication of IE38141B1 publication Critical patent/IE38141B1/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/455Nicotinic acids, e.g. niacin; Derivatives thereof, e.g. esters, amides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • A61P11/08Bronchodilators
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00Drugs for disorders of the urinary system
    • A61P13/02Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00Drugs for genital or sexual disorders; Contraceptives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/06Antihyperlipidemics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/06Antiarrhythmics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/08Vasodilators for multiple indications
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/12Antihypertensives
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D211/00Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/80Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
    • C07D211/84Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen directly attached to ring carbon atoms
    • C07D211/90Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D409/00Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/04Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Urology & Nephrology (AREA)
  • Epidemiology (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Vascular Medicine (AREA)
  • Endocrinology (AREA)
  • Reproductive Health (AREA)
  • Pulmonology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Quinoline Compounds (AREA)
  • Pyridine Compounds (AREA)
IE1524/73A 1972-08-31 1973-08-30 New 3,4-dihydropyridones their production and their medicinal use IE38141B1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE2242787A DE2242787C2 (de) 1972-08-31 1972-08-31 4-Phenyl-6-amino-3,4-dihydropyridon-(2)-3,5-dicarbonsäure-diäthylesterderivate, ein Verfahren zu deren Herstellung und diese enthaltende Arzneimittel

Publications (2)

Publication Number Publication Date
IE38141L IE38141L (en) 1974-02-28
IE38141B1 true IE38141B1 (en) 1978-01-04

Family

ID=5855065

Family Applications (1)

Application Number Title Priority Date Filing Date
IE1524/73A IE38141B1 (en) 1972-08-31 1973-08-30 New 3,4-dihydropyridones their production and their medicinal use

Country Status (21)

Country Link
US (1) US3925395A (US20110105765A1-20110505-C00013.png)
JP (1) JPS5626661B2 (US20110105765A1-20110505-C00013.png)
AT (1) AT327902B (US20110105765A1-20110505-C00013.png)
AU (1) AU476373B2 (US20110105765A1-20110505-C00013.png)
BE (1) BE804161A (US20110105765A1-20110505-C00013.png)
CA (1) CA1016946A (US20110105765A1-20110505-C00013.png)
CH (1) CH592061A5 (US20110105765A1-20110505-C00013.png)
DD (1) DD109628A5 (US20110105765A1-20110505-C00013.png)
DE (1) DE2242787C2 (US20110105765A1-20110505-C00013.png)
DK (1) DK131855C (US20110105765A1-20110505-C00013.png)
ES (1) ES418340A1 (US20110105765A1-20110505-C00013.png)
FR (1) FR2197598B1 (US20110105765A1-20110505-C00013.png)
GB (1) GB1389505A (US20110105765A1-20110505-C00013.png)
HU (1) HU167992B (US20110105765A1-20110505-C00013.png)
IE (1) IE38141B1 (US20110105765A1-20110505-C00013.png)
IL (1) IL43080A (US20110105765A1-20110505-C00013.png)
LU (1) LU68325A1 (US20110105765A1-20110505-C00013.png)
NL (1) NL7311832A (US20110105765A1-20110505-C00013.png)
PL (1) PL89430B1 (US20110105765A1-20110505-C00013.png)
SE (1) SE385882B (US20110105765A1-20110505-C00013.png)
ZA (1) ZA735973B (US20110105765A1-20110505-C00013.png)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4002762A (en) * 1973-03-03 1977-01-11 Bayer Aktiengesellschaft 2-Amino-3,4-dihydropyridines used to effect coronary vessel dilation and treat hypertension
IT8367883A0 (it) * 1982-08-23 1983-08-22 Rorer Int Overseas Composti cardiotonici del 2 piridone 5 biciclico eteroaril sostituito e relative composizioni farmaceutiche
AU3128693A (en) * 1991-11-18 1993-06-15 G.D. Searle & Co. 2-(4-substituted)phenylmethylene derivatives and methods of use
EP1554246B1 (en) * 2002-08-27 2007-08-22 Bayer HealthCare AG Dihydropyridinone derivatives as hne inhibitors
US20050252833A1 (en) * 2004-05-14 2005-11-17 Doyle James A Process and apparatus for converting oil shale or oil sand (tar sand) to oil

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1923990C3 (de) * 1969-05-10 1978-11-23 Bayer Ag Verfahren zur Herstellung von N-substituierten M-Dihydropyridin-S.S-dicarbonsäureestern
DE2013431C3 (de) * 1970-03-20 1979-12-20 Bayer Ag, 5090 Leverkusen 4-Azidophenyl-l,4-dihydropyridin-3,5-dicarbonsäureester
DE2003146A1 (de) * 1970-01-24 1971-07-29 Bayer Ag Neue 1,4-Dihydropyridinderivate

Also Published As

Publication number Publication date
PL89430B1 (US20110105765A1-20110505-C00013.png) 1976-11-30
IL43080A (en) 1977-01-31
AU476373B2 (en) 1976-09-16
HU167992B (US20110105765A1-20110505-C00013.png) 1976-02-28
NL7311832A (US20110105765A1-20110505-C00013.png) 1974-03-04
SE385882B (sv) 1976-07-26
DK131855B (da) 1975-09-15
LU68325A1 (US20110105765A1-20110505-C00013.png) 1973-10-30
JPS5626661B2 (US20110105765A1-20110505-C00013.png) 1981-06-19
US3925395A (en) 1975-12-09
DE2242787A1 (de) 1974-03-14
DD109628A5 (US20110105765A1-20110505-C00013.png) 1974-11-12
IE38141L (en) 1974-02-28
AT327902B (de) 1976-02-25
CH592061A5 (US20110105765A1-20110505-C00013.png) 1977-10-14
CA1016946A (en) 1977-09-06
FR2197598A1 (US20110105765A1-20110505-C00013.png) 1974-03-29
BE804161A (fr) 1974-02-28
AU5983573A (en) 1975-03-06
ATA760073A (de) 1975-05-15
ZA735973B (en) 1974-10-30
GB1389505A (en) 1975-04-03
ES418340A1 (es) 1976-03-16
DK131855C (da) 1976-02-16
JPS4962483A (US20110105765A1-20110505-C00013.png) 1974-06-17
DE2242787C2 (de) 1982-01-21
IL43080A0 (en) 1973-11-28
FR2197598B1 (US20110105765A1-20110505-C00013.png) 1977-07-15

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