IE37326B1 - Antihypertensive compositions - Google Patents

Antihypertensive compositions

Info

Publication number
IE37326B1
IE37326B1 IE303/73A IE30373A IE37326B1 IE 37326 B1 IE37326 B1 IE 37326B1 IE 303/73 A IE303/73 A IE 303/73A IE 30373 A IE30373 A IE 30373A IE 37326 B1 IE37326 B1 IE 37326B1
Authority
IE
Ireland
Prior art keywords
alkyl
alkoxy
radical
halogen
phenyl
Prior art date
Application number
IE303/73A
Other languages
English (en)
Other versions
IE37326L (en
Original Assignee
Merck & Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck & Co Inc filed Critical Merck & Co Inc
Publication of IE37326L publication Critical patent/IE37326L/xx
Publication of IE37326B1 publication Critical patent/IE37326B1/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D285/00—Heterocyclic compounds containing rings having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by groups C07D275/00 - C07D283/00
    • C07D285/01—Five-membered rings
    • C07D285/02—Thiadiazoles; Hydrogenated thiadiazoles
    • C07D285/04—Thiadiazoles; Hydrogenated thiadiazoles not condensed with other rings
    • C07D285/10—1,2,5-Thiadiazoles; Hydrogenated 1,2,5-thiadiazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/50—Pyridazines; Hydrogenated pyridazines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/54—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
IE303/73A 1972-03-06 1973-02-27 Antihypertensive compositions IE37326B1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US00232294A US3833727A (en) 1972-03-06 1972-03-06 Hydralazine and beta-adrenergic blocking agent compositions for treating hypertension

Publications (2)

Publication Number Publication Date
IE37326L IE37326L (en) 1973-09-06
IE37326B1 true IE37326B1 (en) 1977-06-22

Family

ID=22872572

Family Applications (1)

Application Number Title Priority Date Filing Date
IE303/73A IE37326B1 (en) 1972-03-06 1973-02-27 Antihypertensive compositions

Country Status (19)

Country Link
US (1) US3833727A (xx)
AT (1) AT331966B (xx)
BE (1) BE796288A (xx)
CA (1) CA1015662A (xx)
CY (1) CY951A (xx)
DD (1) DD103559A5 (xx)
FR (1) FR2181786B1 (xx)
GB (1) GB1385648A (xx)
HK (1) HK23378A (xx)
HU (1) HU165714B (xx)
IE (1) IE37326B1 (xx)
IL (1) IL41610A (xx)
KE (1) KE2839A (xx)
LU (1) LU67144A1 (xx)
MY (1) MY7800295A (xx)
NL (1) NL176746C (xx)
PH (1) PH18901A (xx)
SE (1) SE400472B (xx)
ZA (1) ZA731505B (xx)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4001421A (en) * 1971-10-27 1977-01-04 Syntex (U.S.A.) Inc. Thiazole cardiovascular agents
AU540656B2 (en) * 1980-02-19 1984-11-29 Merck & Co., Inc. S-(-)-1-(tert-butylamino-3((4-morpholino-1,2,5-thiadiazol-3- yl)-oxy)-2-propanol pamoate
US4521414A (en) * 1981-06-18 1985-06-04 The Texas A&M University System Ophthalmic compositions and their use for treating elevated intraocular pressure and glaucoma
US20110092507A1 (en) * 2009-10-20 2011-04-21 Chin-Tsai Fan Process for preparing R-(+)-3-morpholino-4-(3- tert-butylamino-2-hydroxypropoxy)-1,2,5-thiadiazole

Also Published As

Publication number Publication date
PH18901A (en) 1985-10-30
AU5266273A (en) 1974-08-29
HK23378A (en) 1978-05-12
NL7302728A (xx) 1973-09-10
HU165714B (xx) 1974-10-28
IL41610A0 (en) 1973-04-30
CY951A (en) 1978-12-22
NL176746C (nl) 1985-06-03
KE2839A (en) 1978-05-26
BE796288A (fr) 1973-09-05
DD103559A5 (xx) 1974-02-05
FR2181786B1 (xx) 1976-05-14
NL176746B (nl) 1985-01-02
MY7800295A (en) 1978-12-31
DE2310836B2 (de) 1976-11-04
US3833727A (en) 1974-09-03
DE2310836A1 (de) 1973-09-20
LU67144A1 (xx) 1973-09-06
GB1385648A (en) 1975-02-26
SE400472B (sv) 1978-04-03
CA1015662A (en) 1977-08-16
IL41610A (en) 1975-08-31
AT331966B (de) 1976-09-10
ZA731505B (en) 1974-10-30
ATA195873A (de) 1975-12-15
FR2181786A1 (xx) 1973-12-07
IE37326L (en) 1973-09-06

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