IE37127L - Purification of kallikrein. - Google Patents

Purification of kallikrein.

Info

Publication number
IE37127L
IE37127L IE721487A IE148772A IE37127L IE 37127 L IE37127 L IE 37127L IE 721487 A IE721487 A IE 721487A IE 148772 A IE148772 A IE 148772A IE 37127 L IE37127 L IE 37127L
Authority
IE
Ireland
Prior art keywords
kallikrein
exchanger
therefrom
component
division
Prior art date
Application number
IE721487A
Other versions
IE37127B1 (en
Original Assignee
Bayer Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from DE2154557A external-priority patent/DE2154557C3/en
Priority claimed from DE19712154556 external-priority patent/DE2154556C3/en
Application filed by Bayer Ag filed Critical Bayer Ag
Publication of IE37127L publication Critical patent/IE37127L/en
Publication of IE37127B1 publication Critical patent/IE37127B1/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/64—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
    • C12N9/6421—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from mammals
    • C12N9/6424—Serine endopeptidases (3.4.21)
    • C12N9/6445—Kallikreins (3.4.21.34; 3.4.21.35)

Abstract

1384335 Medicines comprising kallikreins BAYER AG 2 Now 1972 [3 Nov 1971 (2)] 50559/72 Heading A5B [Also in Division C3] A pharmaceutical composition comprises Kallikrein or Kallikrein component A and/or Kallikrein component B which has been obtained by (1) adsorbing the Kallikrein from an impure solution onto a macroporous anion exchanger and eluting it therefrom to obtain an eluted solution containing Kallikrein; and (2) contacting the eluted solution with a macroporous cation exchanger and separating the exchanger therefrom to produce a pure solu- tion of Kallikrein. The enzyme may be in crystalline form (see Division C3). [GB1384335A]
IE1487/72A 1971-11-03 1972-11-02 Improvements in the purification of kallikrein and its components a and b IE37127B1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE2154557A DE2154557C3 (en) 1971-11-03 1971-11-03 Process for the production of high-purity kallidinogenase (kallikrein) and a medicament containing the crystalline kallidinogenase obtained thereafter
DE19712154556 DE2154556C3 (en) 1971-11-03 1971-11-03 Process for the preparation of crystalline kallidinogenase (kallikrein) components A and B and medicaments containing one of these components

Publications (2)

Publication Number Publication Date
IE37127L true IE37127L (en) 1973-05-03
IE37127B1 IE37127B1 (en) 1977-05-11

Family

ID=25761980

Family Applications (1)

Application Number Title Priority Date Filing Date
IE1487/72A IE37127B1 (en) 1971-11-03 1972-11-02 Improvements in the purification of kallikrein and its components a and b

Country Status (20)

Country Link
JP (1) JPS5716794B2 (en)
AT (1) AT319466B (en)
AU (1) AU463125B2 (en)
BE (1) BE790794A (en)
CA (1) CA989334A (en)
CH (1) CH584547A5 (en)
DD (1) DD103907A5 (en)
DK (1) DK131893C (en)
EG (1) EG10631A (en)
ES (1) ES408158A1 (en)
FI (1) FI51203C (en)
FR (1) FR2158519B1 (en)
GB (1) GB1384335A (en)
HU (1) HU164371B (en)
IE (1) IE37127B1 (en)
IL (1) IL40715A (en)
LU (1) LU66403A1 (en)
NL (1) NL7214730A (en)
NO (1) NO135709C (en)
PL (1) PL85201B1 (en)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5951222A (en) * 1982-09-17 1984-03-24 Wakamoto Pharmaceut Co Ltd Stable kallidinogenase preparation
JPS59205312A (en) * 1982-12-28 1984-11-20 Shunichi Naito Pharmaceutical preparation of kallikrein absorbable through rectum
JPS59137417A (en) * 1983-01-28 1984-08-07 Morinaga Milk Ind Co Ltd Preparation of colonization stimulation factor and kallikrein originated from human urine
JPH05163158A (en) * 1991-12-13 1993-06-29 Sanwa Kagaku Kenkyusho Co Ltd Agent for prevention and treatment of skin sore containing human urinary kininogenase as active component

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE910580C (en) * 1952-08-26 1954-05-03 Bayer Ag Process for obtaining the circulatory hormone kallikrein
FR1284825A (en) * 1960-03-25 1962-02-16 Bayer Ag Process for making extremely purified kallikrein preparations

Also Published As

Publication number Publication date
FI51203C (en) 1976-11-10
JPS4856889A (en) 1973-08-09
CH584547A5 (en) 1977-02-15
DK131893C (en) 1976-02-16
EG10631A (en) 1976-08-31
IE37127B1 (en) 1977-05-11
FR2158519B1 (en) 1976-04-23
GB1384335A (en) 1975-02-19
CA989334A (en) 1976-05-18
PL85201B1 (en) 1976-04-30
IL40715A0 (en) 1973-01-30
BE790794A (en) 1973-04-30
AT319466B (en) 1974-12-27
IL40715A (en) 1975-04-25
DD103907A5 (en) 1974-02-12
AU4846972A (en) 1974-05-02
NL7214730A (en) 1973-05-07
FI51203B (en) 1976-08-02
LU66403A1 (en) 1973-01-23
AU463125B2 (en) 1975-07-17
JPS5716794B2 (en) 1982-04-07
NO135709B (en) 1977-02-07
FR2158519A1 (en) 1973-06-15
NO135709C (en) 1977-05-16
DK131893B (en) 1975-09-22
ES408158A1 (en) 1975-11-16
HU164371B (en) 1974-02-28

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