IE37028B1 - Halogenated phenylthioacetamido cephalosporanic acids - Google Patents

Halogenated phenylthioacetamido cephalosporanic acids

Info

Publication number
IE37028B1
IE37028B1 IE1792/72A IE179272A IE37028B1 IE 37028 B1 IE37028 B1 IE 37028B1 IE 1792/72 A IE1792/72 A IE 1792/72A IE 179272 A IE179272 A IE 179272A IE 37028 B1 IE37028 B1 IE 37028B1
Authority
IE
Ireland
Prior art keywords
examples
block copolymers
siloxane blocks
blocks
polyoxyalkylene
Prior art date
Application number
IE1792/72A
Other versions
IE37028L (en
Original Assignee
Lilly Co Eli
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lilly Co Eli filed Critical Lilly Co Eli
Publication of IE37028L publication Critical patent/IE37028L/en
Publication of IE37028B1 publication Critical patent/IE37028B1/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08JWORKING-UP; GENERAL PROCESSES OF COMPOUNDING; AFTER-TREATMENT NOT COVERED BY SUBCLASSES C08B, C08C, C08F, C08G or C08H
    • C08J9/00Working-up of macromolecular substances to porous or cellular articles or materials; After-treatment thereof
    • C08J9/0061Working-up of macromolecular substances to porous or cellular articles or materials; After-treatment thereof characterized by the use of several polymeric components
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D501/00Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/14Compounds having a nitrogen atom directly attached in position 7
    • C07D501/16Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
    • C07D501/207-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
    • C07D501/247-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids with hydrocarbon radicals, substituted by hetero atoms or hetero rings, attached in position 3
    • C07D501/26Methylene radicals, substituted by oxygen atoms; Lactones thereof with the 2-carboxyl group
    • C07D501/28Methylene radicals, substituted by oxygen atoms; Lactones thereof with the 2-carboxyl group with the 7-amino radical acylated by an aliphatic carboxylic acid, which is substituted by hetero atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D501/00Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/14Compounds having a nitrogen atom directly attached in position 7
    • C07D501/16Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
    • C07D501/207-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
    • C07D501/247-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids with hydrocarbon radicals, substituted by hetero atoms or hetero rings, attached in position 3
    • C07D501/36Methylene radicals, substituted by sulfur atoms
    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08GMACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G18/00Polymeric products of isocyanates or isothiocyanates
    • C08G18/06Polymeric products of isocyanates or isothiocyanates with compounds having active hydrogen
    • C08G18/28Polymeric products of isocyanates or isothiocyanates with compounds having active hydrogen characterised by the compounds used containing active hydrogen
    • C08G18/40High-molecular-weight compounds
    • C08G18/4009Two or more macromolecular compounds not provided for in one single group of groups C08G18/42 - C08G18/64
    • C08G18/4072Mixtures of compounds of group C08G18/63 with other macromolecular compounds
    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08GMACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G77/00Macromolecular compounds obtained by reactions forming a linkage containing silicon with or without sulfur, nitrogen, oxygen or carbon in the main chain of the macromolecule
    • C08G77/42Block-or graft-polymers containing polysiloxane sequences
    • C08G77/46Block-or graft-polymers containing polysiloxane sequences containing polyether sequences
    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08JWORKING-UP; GENERAL PROCESSES OF COMPOUNDING; AFTER-TREATMENT NOT COVERED BY SUBCLASSES C08B, C08C, C08F, C08G or C08H
    • C08J2375/00Characterised by the use of polyureas or polyurethanes; Derivatives of such polymers
    • C08J2375/04Polyurethanes
    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08JWORKING-UP; GENERAL PROCESSES OF COMPOUNDING; AFTER-TREATMENT NOT COVERED BY SUBCLASSES C08B, C08C, C08F, C08G or C08H
    • C08J2483/00Characterised by the use of macromolecular compounds obtained by reactions forming in the main chain of the macromolecule a linkage containing silicon with or without sulfur, nitrogen, oxygen, or carbon only; Derivatives of such polymers

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Chemistry (AREA)
  • Polymers & Plastics (AREA)
  • Engineering & Computer Science (AREA)
  • Materials Engineering (AREA)
  • Cephalosporin Compounds (AREA)
  • Treatments For Attaching Organic Compounds To Fibrous Goods (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Polyurethanes Or Polyureas (AREA)
  • Manufacture Of Porous Articles, And Recovery And Treatment Of Waste Products (AREA)
  • Silicon Polymers (AREA)

Abstract

1383552 Polysiloxane-polyoxyalkylene block copolymers; polyurethane foams UNION CARBIDE CORP 7 March 1972 [8 March 1971 27 Dec 1971] 10599/72 Headings C3R and C3T Polysiloxane-polyoxyalkylene block copolymers have the formula [(R 2 SiO) x (C n H 2n O) y ] d (I), or [Y(R 2 SiO) a R 2 SiYO(C n H 2n O) y ] d (II), wherein each R is a monovalent hydrocarbon radical free of aliphatic unsaturation and Y is a divalent organic group, n is 2-4, x is at least 7, a is at least 6,y is at least 4 and d is at least 4, the average molecular weight of the siloxane blocks being 500-10,000, of the polyoxyalkylene blocks being 300-10,000, and of the copolymer being at least 65,000 for (I) and 30,000 for (II), and the siloxane blocks constituting 20-50 wt. per cent of the copolymer. In examples 1-8 polymers of type (II) are obtained from allylterminated poly - oxyethylene - oxypropylenes containing 65 or 50% oxypropylene units, of MW 2700-3000, and hydrogen-terminated polydimethylsiloxanes of MW 700-2300; they are of MW 36,000-56,000 and contain 21-46 wt. per cent siloxane blocks. In examples 9-26 polymers of type (I) are obtained from polyoxyethylene-oxypropylene glycols containing 0%, 35%, 50%, 75% or 100% oxypropylene units, of MW 2670-3140, and dimethylaminoterminated polydimethylsiloxanes of MW 1140- 1910; they are of MW 5300 to 250,000 and contain 30À4-42% siloxane blocks. In examples 30-34 the block copolymers are used as froth stabilizers in froths obtained by whipping air into a mixture of acrylonitrile-grafted oxypropylated glycerol, oxypropylated glycerol, a polycaprolactone diol and toluene diisocyanate, containing small amounts of Ni acetylacetonate and N,N,N1,N1-tetramethyl-1,3-diaminobutane, and, in Ex. 34, CaCO 3 filler. (From GB1383552 A) [FR2166080A1]
IE1792/72A 1971-12-27 1972-12-28 Halogenated phenylthioacetamido cephalosporanic acids IE37028B1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US21273971A 1971-12-27 1971-12-27

Publications (2)

Publication Number Publication Date
IE37028L IE37028L (en) 1973-06-27
IE37028B1 true IE37028B1 (en) 1977-04-13

Family

ID=22792241

Family Applications (1)

Application Number Title Priority Date Filing Date
IE1792/72A IE37028B1 (en) 1971-12-27 1972-12-28 Halogenated phenylthioacetamido cephalosporanic acids

Country Status (19)

Country Link
JP (2) JPS4885592A (en)
AR (1) AR195312A1 (en)
AT (1) AT322107B (en)
AU (2) AU463521B2 (en)
BE (1) BE793310A (en)
CA (1) CA986099A (en)
CH (1) CH558383A (en)
DE (1) DE2263430C2 (en)
ES (1) ES410248A1 (en)
FR (1) FR2166080B1 (en)
GB (1) GB1405798A (en)
HU (1) HU167747B (en)
IE (1) IE37028B1 (en)
IL (1) IL41161A (en)
NL (1) NL7217699A (en)
PH (1) PH13639A (en)
SE (1) SE417209B (en)
YU (1) YU36043B (en)
ZA (2) ZA729116B (en)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6329363B1 (en) 1997-12-12 2001-12-11 Eli Lilly And Company Cephalosporin antibiotics
DE102006061351A1 (en) * 2006-12-22 2008-06-26 Evonik Goldschmidt Gmbh Process for the preparation of SiOC-linked, linear polydimethylsiloxane-polyoxyalkylene block copolymers and their use
JP4954845B2 (en) * 2007-11-05 2012-06-20 瑞乾 高 Holder for hand tools
WO2018186208A1 (en) 2017-04-04 2018-10-11 旭化成株式会社 Photosensitive resin composition for flexographic printing plate, flexographic printing original plate, flexographic printing plate, and copolymer

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR1321704A (en) * 1962-04-03 1963-03-22 Lilly Co Eli Process for preparing 7- (s-substituted mercapto-acylamido) derivatives of cephalosporins c and novel compounds thus prepared
US3335136A (en) * 1965-12-27 1967-08-08 Lilly Co Eli Halophenylmercaptomethyl cephalosporins

Also Published As

Publication number Publication date
AU463521B2 (en) 1975-07-31
AT322107B (en) 1975-05-12
BE793310A (en) 1973-06-27
AU5054372A (en) 1974-07-04
SE417209B (en) 1981-03-02
CA986099A (en) 1976-03-23
IL41161A0 (en) 1973-02-28
YU36043B (en) 1981-11-13
CH558383A (en) 1975-01-31
IE37028L (en) 1973-06-27
FR2166080B1 (en) 1977-01-28
AU466218B2 (en) 1975-10-23
GB1405798A (en) 1975-09-10
AR195312A1 (en) 1973-09-28
PH13639A (en) 1980-08-18
YU324672A (en) 1981-02-28
AU5054472A (en) 1974-07-04
DE2263430C2 (en) 1983-09-22
ZA729116B (en) 1974-08-28
JPS4885592A (en) 1973-11-13
HU167747B (en) 1975-12-25
DE2263430A1 (en) 1973-07-05
ES410248A1 (en) 1976-04-01
IL41161A (en) 1975-10-15
JPS541840B2 (en) 1979-01-30
JPS50105996A (en) 1975-08-21
FR2166080A1 (en) 1973-08-10
ZA729115B (en) 1974-08-28
NL7217699A (en) 1973-06-29

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