IE36138B1 - New dihydro-1,2,4-benzothiadiazine-1,1-dioxide derivative - Google Patents
New dihydro-1,2,4-benzothiadiazine-1,1-dioxide derivativeInfo
- Publication number
- IE36138B1 IE36138B1 IE273/72A IE27372A IE36138B1 IE 36138 B1 IE36138 B1 IE 36138B1 IE 273/72 A IE273/72 A IE 273/72A IE 27372 A IE27372 A IE 27372A IE 36138 B1 IE36138 B1 IE 36138B1
- Authority
- IE
- Ireland
- Prior art keywords
- alkyl
- groups
- carbon atoms
- radical
- radicals
- Prior art date
Links
- -1 alkyl radical Chemical class 0.000 abstract 5
- 125000004432 carbon atom Chemical group C* 0.000 abstract 3
- UIIMBOGNXHQVGW-UHFFFAOYSA-M Sodium bicarbonate Chemical compound [Na+].OC([O-])=O UIIMBOGNXHQVGW-UHFFFAOYSA-M 0.000 abstract 2
- 150000001875 compounds Chemical class 0.000 abstract 2
- 150000002148 esters Chemical class 0.000 abstract 2
- 125000002485 formyl group Chemical class [H]C(*)=O 0.000 abstract 2
- NYGLDJNOHMOLOI-UHFFFAOYSA-N 1,1-dioxo-3,4-dihydro-2H-1lambda6,2,4-benzothiadiazin-5-amine Chemical compound NC1=CC=CC2=C1NCNS2(=O)=O NYGLDJNOHMOLOI-UHFFFAOYSA-N 0.000 abstract 1
- SLRMQYXOBQWXCR-UHFFFAOYSA-N 2154-56-5 Chemical class [CH2]C1=CC=CC=C1 SLRMQYXOBQWXCR-UHFFFAOYSA-N 0.000 abstract 1
- WKBOTKDWSSQWDR-UHFFFAOYSA-N Bromine atom Chemical compound [Br] WKBOTKDWSSQWDR-UHFFFAOYSA-N 0.000 abstract 1
- ZAMOUSCENKQFHK-UHFFFAOYSA-N Chlorine atom Chemical compound [Cl] ZAMOUSCENKQFHK-UHFFFAOYSA-N 0.000 abstract 1
- CIUQDSCDWFSTQR-UHFFFAOYSA-N [C]1=CC=CC=C1 Chemical class [C]1=CC=CC=C1 CIUQDSCDWFSTQR-UHFFFAOYSA-N 0.000 abstract 1
- DHKHKXVYLBGOIT-UHFFFAOYSA-N acetaldehyde Diethyl Acetal Natural products CCOC(C)OCC DHKHKXVYLBGOIT-UHFFFAOYSA-N 0.000 abstract 1
- 125000002777 acetyl group Chemical class [H]C([H])([H])C(*)=O 0.000 abstract 1
- 239000002253 acid Substances 0.000 abstract 1
- 125000000217 alkyl group Chemical group 0.000 abstract 1
- 239000012752 auxiliary agent Substances 0.000 abstract 1
- GDTBXPJZTBHREO-UHFFFAOYSA-N bromine Substances BrBr GDTBXPJZTBHREO-UHFFFAOYSA-N 0.000 abstract 1
- 229910052794 bromium Inorganic materials 0.000 abstract 1
- 125000003178 carboxy group Chemical group [H]OC(*)=O 0.000 abstract 1
- 239000000969 carrier Substances 0.000 abstract 1
- 229910052801 chlorine Inorganic materials 0.000 abstract 1
- 239000000460 chlorine Substances 0.000 abstract 1
- 230000001882 diuretic effect Effects 0.000 abstract 1
- 125000001188 haloalkyl group Chemical group 0.000 abstract 1
- 125000005843 halogen group Chemical group 0.000 abstract 1
- 229910052739 hydrogen Inorganic materials 0.000 abstract 1
- 239000001257 hydrogen Substances 0.000 abstract 1
- 125000004435 hydrogen atom Chemical class [H]* 0.000 abstract 1
- 125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 1
- 238000007911 parenteral administration Methods 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 150000003254 radicals Chemical class 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- HZPGMLMARJYLFJ-UHFFFAOYSA-M sodium 3-(benzylamino)-4-(butylamino)-5-sulfamoylbenzoate trihydrate Chemical compound O.O.O.C(C1=CC=CC=C1)NC=1C=C(C(=O)[O-])C=C(C1NCCCC)S(N)(=O)=O.[Na+] HZPGMLMARJYLFJ-UHFFFAOYSA-M 0.000 abstract 1
- 229910000030 sodium bicarbonate Inorganic materials 0.000 abstract 1
- 235000017557 sodium bicarbonate Nutrition 0.000 abstract 1
- 125000003396 thiol group Chemical group [H]S* 0.000 abstract 1
- 125000002023 trifluoromethyl group Chemical group FC(F)(F)* 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D285/00—Heterocyclic compounds containing rings having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by groups C07D275/00 - C07D283/00
- C07D285/15—Six-membered rings
- C07D285/16—Thiadiazines; Hydrogenated thiadiazines
- C07D285/18—1,2,4-Thiadiazines; Hydrogenated 1,2,4-thiadiazines
- C07D285/20—1,2,4-Thiadiazines; Hydrogenated 1,2,4-thiadiazines condensed with carbocyclic rings or ring systems
- C07D285/22—1,2,4-Thiadiazines; Hydrogenated 1,2,4-thiadiazines condensed with carbocyclic rings or ring systems condensed with one six-membered ring
- C07D285/24—1,2,4-Thiadiazines; Hydrogenated 1,2,4-thiadiazines condensed with carbocyclic rings or ring systems condensed with one six-membered ring with oxygen atoms directly attached to the ring sulfur atom
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB831771 | 1971-03-31 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| IE36138L IE36138L (en) | 1972-09-30 |
| IE36138B1 true IE36138B1 (en) | 1976-09-01 |
Family
ID=9850217
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IE273/72A IE36138B1 (en) | 1971-03-31 | 1972-03-06 | New dihydro-1,2,4-benzothiadiazine-1,1-dioxide derivative |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US3845045A (https=) |
| DE (1) | DE2215864A1 (https=) |
| FR (1) | FR2132202B1 (https=) |
| GB (1) | GB1330033A (https=) |
| IE (1) | IE36138B1 (https=) |
| NL (1) | NL7203343A (https=) |
-
1971
- 1971-03-31 GB GB831771A patent/GB1330033A/en not_active Expired
-
1972
- 1972-03-06 IE IE273/72A patent/IE36138B1/xx unknown
- 1972-03-08 US US00232963A patent/US3845045A/en not_active Expired - Lifetime
- 1972-03-14 NL NL7203343A patent/NL7203343A/xx unknown
- 1972-03-29 FR FR7211103A patent/FR2132202B1/fr not_active Expired
- 1972-03-30 DE DE19722215864 patent/DE2215864A1/de active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| IE36138L (en) | 1972-09-30 |
| US3845045A (en) | 1974-10-29 |
| GB1330033A (en) | 1973-09-12 |
| FR2132202B1 (https=) | 1975-06-20 |
| NL7203343A (https=) | 1972-10-03 |
| FR2132202A1 (https=) | 1972-11-17 |
| DE2215864A1 (de) | 1972-10-12 |
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