IE36094B1 - Antibiotic a-4696 - Google Patents
Antibiotic a-4696Info
- Publication number
- IE36094B1 IE36094B1 IE197/72A IE19772A IE36094B1 IE 36094 B1 IE36094 B1 IE 36094B1 IE 197/72 A IE197/72 A IE 197/72A IE 19772 A IE19772 A IE 19772A IE 36094 B1 IE36094 B1 IE 36094B1
- Authority
- IE
- Ireland
- Prior art keywords
- antibiotic
- pharmaceutically acceptable
- acceptable salt
- feb
- culture medium
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q11/00—Preparations for care of the teeth, of the oral cavity or of dentures; Dentifrices, e.g. toothpastes; Mouth rinses
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23K—FODDER
- A23K20/00—Accessory food factors for animal feeding-stuffs
- A23K20/10—Organic substances
- A23K20/195—Antibiotics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/99—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from microorganisms other than algae or fungi, e.g. protozoa or bacteria
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/02—Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
Abstract
1345676 The antibiotic A-4696 ELI LILLY & CO 24 Feb 1972 [25 Feb 1971] 8697/72 Heading C2A The invention comprises an antibiotic designated A-4696 whose hydrochloride salt is a white crystalline substance soluble in water and insoluble in common organic solvents, has a m.p. greater than 220‹ C.; has an electromeric titration curve in 66% by weight aqueous dimethylformamide approximating a straight line with a slope of about 0À14 from pH 6À0 to pH 13À0; has the approximate composition 51À33% C; 5À79% H; 5À46% N; 30À96% 0; 6À72% Cl; has an apparent M.W. of 1158 as determined by vapour pressure osmometry; has a specific rotation at 25‹ C. at the sodium D line of -42À3‹ (C=1, H 2 O); has an ultraviolet absorption spectrum in acidic and neutral solutions at 276 mÁ with an extinction coefficient E<SP>1%</SP> km of 45, and in a basic solution a single absorption maximum at 300 mÁ with an extinction coefficient E<SP>1%</SP> km of 65, and has an infra-red absorption spectrum as shown in Fig. 1. A method of producing the antibiotic A-4696 comprises cultivating the organic Actinoplenes sp. strain ATCC. 23342, in a liquid culture medium containing assimilable sources of carbon, nitrogen and inorganic salts under submerged aerobic conditions until a substantial amount of antibiotic activity is imparted by the organism to the culture medium. The invention also comprises a pharmaceutical composition which contains antibiotic A-4696 or a pharmaceutically acceptable salt thereof in conjunction with a pharmaceutically acceptable excipient or carrier. Further, a method of treating bacterial infections in warm blooded animals, excluding man, comprises the administration of the antibiotic A-4696, a pharmaceutically acceptable salt thereof or a pharmaceutical composition thereof. Still further a method of producing weight gain in growing poultry comprises feeding the poultry a feed composition containing the antibiotic A-4696 or a pharmaceutically acceptable salt thereof in conjunction with a carrier.
[GB1345676A]
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US11867471A | 1971-02-25 | 1971-02-25 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| IE36094L IE36094L (en) | 1972-08-25 |
| IE36094B1 true IE36094B1 (en) | 1976-08-18 |
Family
ID=22380060
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IE197/72A IE36094B1 (en) | 1971-02-25 | 1972-02-17 | Antibiotic a-4696 |
Country Status (27)
| Country | Link |
|---|---|
| JP (2) | JPS5610032B1 (en) |
| AR (1) | AR193848A1 (en) |
| AT (1) | AT315368B (en) |
| AU (1) | AU463037B2 (en) |
| BE (1) | BE778901A (en) |
| CA (1) | CA986047A (en) |
| CH (1) | CH567572A5 (en) |
| CS (1) | CS167970B2 (en) |
| CY (1) | CY896A (en) |
| DD (1) | DD96507A5 (en) |
| DE (1) | DE2209018C2 (en) |
| DK (1) | DK137863B (en) |
| FR (1) | FR2126415B1 (en) |
| GB (1) | GB1345676A (en) |
| HK (1) | HK28077A (en) |
| HU (1) | HU165526B (en) |
| IE (1) | IE36094B1 (en) |
| IL (1) | IL38693A (en) |
| KE (1) | KE2716A (en) |
| MY (1) | MY7700262A (en) |
| NL (1) | NL175196C (en) |
| PH (1) | PH9416A (en) |
| PL (1) | PL88977B1 (en) |
| SE (1) | SE379053B (en) |
| SU (2) | SU403133A3 (en) |
| YU (1) | YU35621B (en) |
| ZA (1) | ZA72622B (en) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS5424801A (en) * | 1977-07-28 | 1979-02-24 | Karupisu Shiyokuhin Kougiyou K | Novel antibiotics cc3603 and process for preparing same |
| JPS57142849A (en) * | 1982-01-22 | 1982-09-03 | Toyo Kagaku Kk | Bag body for packing |
| JPS5921937U (en) * | 1982-07-31 | 1984-02-10 | 大日本印刷株式会社 | Sealed bag with opening |
| ZA847900B (en) * | 1983-11-28 | 1985-06-26 | Canadian Ind | Shipping bag |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4064233A (en) * | 1974-12-17 | 1977-12-20 | Eli Lilly And Company | Antibiotic A-4696 |
-
1972
- 1972-01-31 ZA ZA720622A patent/ZA72622B/en unknown
- 1972-02-03 IL IL38693A patent/IL38693A/en unknown
- 1972-02-03 BE BE778901A patent/BE778901A/en not_active IP Right Cessation
- 1972-02-04 AU AU38656/72A patent/AU463037B2/en not_active Expired
- 1972-02-15 SE SE7201778A patent/SE379053B/xx unknown
- 1972-02-17 IE IE197/72A patent/IE36094B1/en unknown
- 1972-02-18 CA CA135,033A patent/CA986047A/en not_active Expired
- 1972-02-22 SU SU1750701A patent/SU403133A3/ru active
- 1972-02-22 SU SU1813690A patent/SU417925A3/ru active
- 1972-02-23 NL NLAANVRAGE7202390,A patent/NL175196C/en not_active IP Right Cessation
- 1972-02-23 YU YU448/72A patent/YU35621B/en unknown
- 1972-02-23 PL PL1972153634A patent/PL88977B1/pl unknown
- 1972-02-24 CY CY896A patent/CY896A/en unknown
- 1972-02-24 DK DK85772AA patent/DK137863B/en not_active IP Right Cessation
- 1972-02-24 GB GB869772A patent/GB1345676A/en not_active Expired
- 1972-02-24 HU HUEI409A patent/HU165526B/hu unknown
- 1972-02-25 DD DD161130A patent/DD96507A5/xx unknown
- 1972-02-25 AT AT156372A patent/AT315368B/en not_active IP Right Cessation
- 1972-02-25 AR AR240709A patent/AR193848A1/en active
- 1972-02-25 DE DE2209018A patent/DE2209018C2/en not_active Expired
- 1972-02-25 PH PH13293*UA patent/PH9416A/en unknown
- 1972-02-25 CS CS1235A patent/CS167970B2/cs unknown
- 1972-02-25 CH CH275672A patent/CH567572A5/xx not_active IP Right Cessation
- 1972-02-25 FR FR7206458A patent/FR2126415B1/fr not_active Expired
- 1972-02-25 JP JP1961072A patent/JPS5610032B1/ja active Pending
-
1977
- 1977-03-30 KE KE2716A patent/KE2716A/en unknown
- 1977-06-02 HK HK280/77A patent/HK28077A/en unknown
- 1977-12-30 MY MY262/77A patent/MY7700262A/en unknown
-
1979
- 1979-07-13 JP JP8920079A patent/JPS5592660A/en active Granted
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