IE35537B1 - Naphthoquinone derivatives and a process for the manufacture thereof - Google Patents
Naphthoquinone derivatives and a process for the manufacture thereofInfo
- Publication number
- IE35537B1 IE35537B1 IE888/71A IE88871A IE35537B1 IE 35537 B1 IE35537 B1 IE 35537B1 IE 888/71 A IE888/71 A IE 888/71A IE 88871 A IE88871 A IE 88871A IE 35537 B1 IE35537 B1 IE 35537B1
- Authority
- IE
- Ireland
- Prior art keywords
- compound
- reaction
- prepared
- formula
- halogen
- Prior art date
Links
- 150000002791 naphthoquinones Chemical class 0.000 title abstract 2
- 229930192627 Naphthoquinone Natural products 0.000 title 1
- 238000004519 manufacturing process Methods 0.000 title 1
- 238000000034 method Methods 0.000 title 1
- 150000001875 compounds Chemical class 0.000 abstract 7
- WEVYAHXRMPXWCK-UHFFFAOYSA-N Acetonitrile Chemical compound CC#N WEVYAHXRMPXWCK-UHFFFAOYSA-N 0.000 abstract 6
- 238000006243 chemical reaction Methods 0.000 abstract 5
- 229910052736 halogen Inorganic materials 0.000 abstract 4
- 150000002367 halogens Chemical class 0.000 abstract 4
- WFDIJRYMOXRFFG-UHFFFAOYSA-N Acetic anhydride Chemical compound CC(=O)OC(C)=O WFDIJRYMOXRFFG-UHFFFAOYSA-N 0.000 abstract 3
- -1 nitro, amino Chemical group 0.000 abstract 3
- 125000003545 alkoxy group Chemical group 0.000 abstract 2
- 150000001412 amines Chemical class 0.000 abstract 2
- 229910052801 chlorine Inorganic materials 0.000 abstract 2
- 239000000460 chlorine Substances 0.000 abstract 2
- 230000007062 hydrolysis Effects 0.000 abstract 2
- 238000006460 hydrolysis reaction Methods 0.000 abstract 2
- 125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 2
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 2
- 150000003839 salts Chemical class 0.000 abstract 2
- JYMKCDRRMPKNNP-UHFFFAOYSA-N 4,7,7-trimethyl-3-(2-phenylethyl)bicyclo[2.2.1]heptan-3-ol Chemical compound CC1(C)C(C2)CCC1(C)C2(O)CCC1=CC=CC=C1 JYMKCDRRMPKNNP-UHFFFAOYSA-N 0.000 abstract 1
- 101000653791 Bos taurus Protein S100-A12 Proteins 0.000 abstract 1
- HHVUQMSPLDFGMI-UHFFFAOYSA-N C1(=CC=CC=C1)C(C)=C1C2C(C)(C)C(C1)(C)CC2 Chemical compound C1(=CC=CC=C1)C(C)=C1C2C(C)(C)C(C1)(C)CC2 HHVUQMSPLDFGMI-UHFFFAOYSA-N 0.000 abstract 1
- ZAMOUSCENKQFHK-UHFFFAOYSA-N Chlorine atom Chemical compound [Cl] ZAMOUSCENKQFHK-UHFFFAOYSA-N 0.000 abstract 1
- 125000003047 N-acetyl group Chemical group 0.000 abstract 1
- 150000001242 acetic acid derivatives Chemical class 0.000 abstract 1
- 239000002253 acid Substances 0.000 abstract 1
- 125000004423 acyloxy group Chemical group 0.000 abstract 1
- 125000000217 alkyl group Chemical group 0.000 abstract 1
- 230000003569 amebicidal effect Effects 0.000 abstract 1
- 125000004659 aryl alkyl thio group Chemical group 0.000 abstract 1
- 125000005110 aryl thio group Chemical group 0.000 abstract 1
- 125000004104 aryloxy group Chemical group 0.000 abstract 1
- 230000003385 bacteriostatic effect Effects 0.000 abstract 1
- 125000001309 chloro group Chemical group Cl* 0.000 abstract 1
- 238000002425 crystallisation Methods 0.000 abstract 1
- 230000008025 crystallization Effects 0.000 abstract 1
- OJOGWANOVVZJQO-UHFFFAOYSA-N hept-1-yne 1,7,7-trimethylbicyclo[2.2.1]heptan-2-one Chemical compound C#CCCCCC.C12(C(=O)CC(CC1)C2(C)C)C OJOGWANOVVZJQO-UHFFFAOYSA-N 0.000 abstract 1
- FRIJBUGBVQZNTB-UHFFFAOYSA-M magnesium;ethane;bromide Chemical compound [Mg+2].[Br-].[CH2-]C FRIJBUGBVQZNTB-UHFFFAOYSA-M 0.000 abstract 1
- 238000006396 nitration reaction Methods 0.000 abstract 1
- 125000006501 nitrophenyl group Chemical group 0.000 abstract 1
- 230000003647 oxidation Effects 0.000 abstract 1
- 238000007254 oxidation reaction Methods 0.000 abstract 1
- 150000002923 oximes Chemical class 0.000 abstract 1
- 238000007911 parenteral administration Methods 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 238000000926 separation method Methods 0.000 abstract 1
- LMBFAGIMSUYTBN-MPZNNTNKSA-N teixobactin Chemical compound C([C@H](C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CO)C(=O)N[C@H](CCC(N)=O)C(=O)N[C@H]([C@@H](C)CC)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CO)C(=O)N[C@H]1C(N[C@@H](C)C(=O)N[C@@H](C[C@@H]2NC(=N)NC2)C(=O)N[C@H](C(=O)O[C@H]1C)[C@@H](C)CC)=O)NC)C1=CC=CC=C1 LMBFAGIMSUYTBN-MPZNNTNKSA-N 0.000 abstract 1
- DLFVBJFMPXGRIB-UHFFFAOYSA-N thioacetamide Natural products CC(N)=O DLFVBJFMPXGRIB-UHFFFAOYSA-N 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C225/00—Compounds containing amino groups and doubly—bound oxygen atoms bound to the same carbon skeleton, at least one of the doubly—bound oxygen atoms not being part of a —CHO group, e.g. amino ketones
- C07C225/24—Compounds containing amino groups and doubly—bound oxygen atoms bound to the same carbon skeleton, at least one of the doubly—bound oxygen atoms not being part of a —CHO group, e.g. amino ketones the carbon skeleton containing carbon atoms of quinone rings
- C07C225/26—Compounds containing amino groups and doubly—bound oxygen atoms bound to the same carbon skeleton, at least one of the doubly—bound oxygen atoms not being part of a —CHO group, e.g. amino ketones the carbon skeleton containing carbon atoms of quinone rings having amino groups bound to carbon atoms of quinone rings or of condensed ring systems containing quinone rings
- C07C225/30—Compounds containing amino groups and doubly—bound oxygen atoms bound to the same carbon skeleton, at least one of the doubly—bound oxygen atoms not being part of a —CHO group, e.g. amino ketones the carbon skeleton containing carbon atoms of quinone rings having amino groups bound to carbon atoms of quinone rings or of condensed ring systems containing quinone rings of condensed quinone ring systems formed by two rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B2200/00—Indexing scheme relating to specific properties of organic compounds
- C07B2200/07—Optical isomers
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2602/00—Systems containing two condensed rings
- C07C2602/02—Systems containing two condensed rings the rings having only two atoms in common
- C07C2602/04—One of the condensed rings being a six-membered aromatic ring
- C07C2602/10—One of the condensed rings being a six-membered aromatic ring the other ring being six-membered, e.g. tetraline
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2602/00—Systems containing two condensed rings
- C07C2602/36—Systems containing two condensed rings the rings having more than two atoms in common
- C07C2602/42—Systems containing two condensed rings the rings having more than two atoms in common the bicyclo ring system containing seven carbon atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Catalysts (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CH1090570A CH548984A (de) | 1970-07-17 | 1970-07-17 | Verfahren zur herstellung von naphthochinonderivaten. |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| IE35537L IE35537L (en) | 1972-01-17 |
| IE35537B1 true IE35537B1 (en) | 1976-03-18 |
Family
ID=4368056
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IE888/71A IE35537B1 (en) | 1970-07-17 | 1971-07-13 | Naphthoquinone derivatives and a process for the manufacture thereof |
Country Status (22)
| Country | Link |
|---|---|
| US (1) | US3729492A (cs) |
| AT (2) | AT317191B (cs) |
| BE (1) | BE770109A (cs) |
| BG (1) | BG19587A3 (cs) |
| BR (1) | BR7104493D0 (cs) |
| CA (1) | CA983044A (cs) |
| CH (1) | CH548984A (cs) |
| CS (1) | CS157720B2 (cs) |
| DE (1) | DE2135712A1 (cs) |
| ES (1) | ES393339A1 (cs) |
| FR (1) | FR2100926B1 (cs) |
| GB (1) | GB1314118A (cs) |
| HU (1) | HU162585B (cs) |
| IE (1) | IE35537B1 (cs) |
| IL (1) | IL37228A (cs) |
| MY (1) | MY7400008A (cs) |
| NL (1) | NL7109717A (cs) |
| NO (1) | NO134208C (cs) |
| OA (1) | OA03901A (cs) |
| RO (1) | RO59593A (cs) |
| SE (1) | SE377798B (cs) |
| ZA (1) | ZA714392B (cs) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE2456655A1 (de) * | 1974-01-10 | 1975-07-17 | Hoffmann La Roche | Naphthochinonderivate |
-
1970
- 1970-07-17 CH CH1090570A patent/CH548984A/xx not_active IP Right Cessation
-
1971
- 1971-06-30 BG BG017939A patent/BG19587A3/xx unknown
- 1971-07-05 IL IL37228A patent/IL37228A/xx unknown
- 1971-07-05 ZA ZA714392A patent/ZA714392B/xx unknown
- 1971-07-09 US US00162029A patent/US3729492A/en not_active Expired - Lifetime
- 1971-07-13 CS CS515271A patent/CS157720B2/cs unknown
- 1971-07-13 IE IE888/71A patent/IE35537B1/xx unknown
- 1971-07-14 NL NL7109717A patent/NL7109717A/xx unknown
- 1971-07-15 CA CA118,290A patent/CA983044A/en not_active Expired
- 1971-07-15 HU HUHO1394A patent/HU162585B/hu unknown
- 1971-07-15 BR BR4493/71A patent/BR7104493D0/pt unknown
- 1971-07-15 FR FR7125896A patent/FR2100926B1/fr not_active Expired
- 1971-07-16 AT AT620571A patent/AT317191B/de not_active IP Right Cessation
- 1971-07-16 NO NO2739/71A patent/NO134208C/no unknown
- 1971-07-16 AT AT471673*1A patent/AT321902B/de not_active IP Right Cessation
- 1971-07-16 OA OA54306A patent/OA03901A/xx unknown
- 1971-07-16 GB GB3347571A patent/GB1314118A/en not_active Expired
- 1971-07-16 DE DE19712135712 patent/DE2135712A1/de active Pending
- 1971-07-16 ES ES393339A patent/ES393339A1/es not_active Expired
- 1971-07-16 BE BE770109A patent/BE770109A/xx unknown
- 1971-07-16 SE SE7109227A patent/SE377798B/xx unknown
- 1971-07-17 RO RO67704A patent/RO59593A/ro unknown
-
1974
- 1974-12-30 MY MY8/74A patent/MY7400008A/xx unknown
Also Published As
| Publication number | Publication date |
|---|---|
| RO59593A (cs) | 1976-07-15 |
| US3729492A (en) | 1973-04-24 |
| NO134208B (cs) | 1976-05-24 |
| GB1314118A (en) | 1973-04-18 |
| IL37228A (en) | 1974-07-31 |
| IL37228A0 (en) | 1971-10-20 |
| NL7109717A (cs) | 1972-01-19 |
| HU162585B (cs) | 1973-03-28 |
| BE770109A (fr) | 1972-01-17 |
| BR7104493D0 (pt) | 1973-03-08 |
| AT321902B (de) | 1975-04-25 |
| CA983044A (en) | 1976-02-03 |
| AT317191B (de) | 1974-08-12 |
| MY7400008A (en) | 1974-12-31 |
| CH548984A (de) | 1974-05-15 |
| ZA714392B (en) | 1972-02-23 |
| OA03901A (fr) | 1975-08-14 |
| ES393339A1 (es) | 1973-08-16 |
| BG19587A3 (bg) | 1975-06-25 |
| SE377798B (cs) | 1975-07-28 |
| SU439964A3 (ru) | 1974-08-15 |
| CS157720B2 (cs) | 1974-09-16 |
| DE2135712A1 (de) | 1972-01-20 |
| IE35537L (en) | 1972-01-17 |
| FR2100926A1 (cs) | 1972-03-24 |
| FR2100926B1 (cs) | 1974-09-06 |
| NO134208C (cs) | 1976-09-01 |
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