IE34665B1 - Isothioureas and their derivatives - Google Patents
Isothioureas and their derivativesInfo
- Publication number
- IE34665B1 IE34665B1 IE1345/70A IE134570A IE34665B1 IE 34665 B1 IE34665 B1 IE 34665B1 IE 1345/70 A IE1345/70 A IE 1345/70A IE 134570 A IE134570 A IE 134570A IE 34665 B1 IE34665 B1 IE 34665B1
- Authority
- IE
- Ireland
- Prior art keywords
- oct
- pharmaceutically acceptable
- nucleus
- forms
- gb1296544a
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
- C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
- C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D231/12—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/64—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms, e.g. histidine
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
- C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
- C07D249/04—1,2,3-Triazoles; Hydrogenated 1,2,3-triazoles
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
- C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
- C07D249/08—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Pyridine Compounds (AREA)
Abstract
1296544 Antihistamines SMITH KLINE & FRENCH LABORATORIES Ltd 26 Oct 1970 [29 Oct 1969] 52890/69 Heading A5B [Also in Division C2] Pharmaceutical compositions in conventional forms and having antihistamine activity other than at the H1 site comprise a pharmaceutically acceptable carrier and a comcompound of formula wherein n is from 2 to 4; A is such that it forms with the carbon and nitrogen atom shown an unsaturated heterocyclic basic nucleus having five or six atoms, which nucleus may be substituted by one or more halogen or aralkyl groups; R 1 is hydrogen or lower alkyl, R 2 together form an ethylene bridge; or its pharmaceutically acceptable acid addition salts, but excluding simple solutions in absolute ethanol of S-[2-(4(5)-imidazolyl) ethyl] isothiourea.
[GB1296544A]
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB5289069 | 1969-10-29 |
Publications (2)
Publication Number | Publication Date |
---|---|
IE34665L IE34665L (en) | 1971-04-29 |
IE34665B1 true IE34665B1 (en) | 1975-07-09 |
Family
ID=10465720
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IE1345/70A IE34665B1 (en) | 1969-10-29 | 1970-10-19 | Isothioureas and their derivatives |
Country Status (9)
Country | Link |
---|---|
JP (1) | JPS4917262B1 (en) |
BE (1) | BE758145A (en) |
CA (1) | CA953725A (en) |
DE (1) | DE2052692A1 (en) |
FR (1) | FR2070177B1 (en) |
GB (1) | GB1296544A (en) |
IE (1) | IE34665B1 (en) |
SE (1) | SE390303B (en) |
ZA (1) | ZA707150B (en) |
Families Citing this family (12)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CA938556A (en) * | 1970-06-25 | 1973-12-18 | Smith Kline And French Laboratories Limited | Pharmaceutical compositions containing thiourea derivatives |
GB1338169A (en) * | 1971-03-09 | 1973-11-21 | Smith Kline French Lab | Ureas thioureas and guanidines |
GB1397436A (en) * | 1972-09-05 | 1975-06-11 | Smith Kline French Lab | Heterocyclic n-cyanoguinidines |
ZA782129B (en) | 1977-04-20 | 1979-03-28 | Ici Ltd | Hertocyclic derivatives |
US4262125A (en) * | 1979-07-23 | 1981-04-14 | American Home Products Corporation | (1H-Imidazol-5-ylmethyl)isothioureas |
IT1201523B (en) * | 1982-05-18 | 1989-02-02 | Angeli Inst Spa | HETEROCYCLYLPHENYLPHOMRAMIDIN, PROCESSES FOR THEIR PREPARATION AND THEIR PHARMACEUTICAL USE |
US4520025A (en) * | 1982-07-21 | 1985-05-28 | William H. Rorer, Inc. | Bicyclic nitrogen heterocyclic ethers and thioethers, and their pharmaceutical uses |
US5321039A (en) * | 1990-04-13 | 1994-06-14 | Societe Civile Bioprojet | Method of inducing a histamine agonist action on H2 receptors |
FR2660862B1 (en) * | 1990-04-13 | 1994-09-23 | Bioprojet Soc Civ | THERAPEUTIC APPLICATION OF HISTAMINE DERIVATIVES, NEW HISTAMINE DERIVATIVE AND USE OF THESE DERIVATIVES FOR THE PREPARATION OF MEDICAMENTS. |
NL9100365A (en) * | 1991-02-27 | 1992-09-16 | Seed Capital Investments | New imidazole compounds with activity at histamine H3 receptor - e.g. S-(2-(4-imidazolyl)ethyl)isothiourea (VUF 8325) |
DE69222757T2 (en) * | 1991-02-27 | 1998-02-12 | Seed Capital Investments | IMIDAZOLE DERIVATIVES WITH ANTAGONISTIC ACTIVITY ON THE HISTAMINE H3 RECEPTOR |
GB0404434D0 (en) * | 2004-02-27 | 2004-03-31 | Novartis Ag | Organic compounds |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US2548746A (en) * | 1947-10-10 | 1951-04-10 | Sharp & Dohme Inc | S-(4-thiazolylmethyl)-isothioureas |
IL25931A (en) * | 1965-07-07 | 1972-01-27 | Merck & Co Inc | New 4-or 5-nitro imidazole and 5,6-dihydroimidazo(1,2-a)pyrrol-7-yl-carbamates and pseudo thioureido imidazoles and their preparation |
-
0
- BE BE758145D patent/BE758145A/en unknown
-
1969
- 1969-10-29 GB GB5289069A patent/GB1296544A/en not_active Expired
-
1970
- 1970-10-19 IE IE1345/70A patent/IE34665B1/en unknown
- 1970-10-22 SE SE7014259A patent/SE390303B/en unknown
- 1970-10-24 JP JP45093878A patent/JPS4917262B1/ja active Pending
- 1970-10-27 DE DE19702052692 patent/DE2052692A1/en active Pending
- 1970-10-27 CA CA096,673A patent/CA953725A/en not_active Expired
- 1970-10-29 FR FR7039077A patent/FR2070177B1/fr not_active Expired
- 1970-10-29 ZA ZA707150A patent/ZA707150B/en unknown
Also Published As
Publication number | Publication date |
---|---|
DE2052692A1 (en) | 1971-05-06 |
GB1296544A (en) | 1972-11-15 |
SE390303B (en) | 1976-12-13 |
JPS4917262B1 (en) | 1974-04-27 |
IE34665L (en) | 1971-04-29 |
BE758145A (en) | 1971-04-28 |
FR2070177B1 (en) | 1974-10-11 |
CA953725A (en) | 1974-08-27 |
ZA707150B (en) | 1971-07-28 |
FR2070177A1 (en) | 1971-09-10 |
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