IE34629B1 - Benzodiazepine derivatives - Google Patents
Benzodiazepine derivativesInfo
- Publication number
- IE34629B1 IE34629B1 IE851/70A IE85170A IE34629B1 IE 34629 B1 IE34629 B1 IE 34629B1 IE 851/70 A IE851/70 A IE 851/70A IE 85170 A IE85170 A IE 85170A IE 34629 B1 IE34629 B1 IE 34629B1
- Authority
- IE
- Ireland
- Prior art keywords
- alkyl
- derivative
- hydrolysing
- treating
- product
- Prior art date
Links
- 229940053197 benzodiazepine derivative antiepileptics Drugs 0.000 title 1
- 125000003310 benzodiazepinyl group Chemical class N1N=C(C=CC2=C1C=CC=C2)* 0.000 title 1
- 125000000217 alkyl group Chemical group 0.000 abstract 3
- 150000001875 compounds Chemical class 0.000 abstract 3
- 230000003301 hydrolyzing effect Effects 0.000 abstract 2
- 101000653791 Bos taurus Protein S100-A12 Proteins 0.000 abstract 1
- 238000007126 N-alkylation reaction Methods 0.000 abstract 1
- 239000004480 active ingredient Substances 0.000 abstract 1
- -1 alkyl lithium Chemical compound 0.000 abstract 1
- 229940125681 anticonvulsant agent Drugs 0.000 abstract 1
- 239000001961 anticonvulsive agent Substances 0.000 abstract 1
- 229940049706 benzodiazepine Drugs 0.000 abstract 1
- 150000001557 benzodiazepines Chemical class 0.000 abstract 1
- 125000001589 carboacyl group Chemical group 0.000 abstract 1
- 239000003795 chemical substances by application Substances 0.000 abstract 1
- 239000012954 diazonium Substances 0.000 abstract 1
- 150000001989 diazonium salts Chemical class 0.000 abstract 1
- 229910052736 halogen Inorganic materials 0.000 abstract 1
- 150000002367 halogens Chemical class 0.000 abstract 1
- 229910052744 lithium Inorganic materials 0.000 abstract 1
- 125000001570 methylene group Chemical group [H]C([H])([*:1])[*:2] 0.000 abstract 1
- 229940035363 muscle relaxants Drugs 0.000 abstract 1
- 239000003158 myorelaxant agent Substances 0.000 abstract 1
- 230000003647 oxidation Effects 0.000 abstract 1
- 238000007254 oxidation reaction Methods 0.000 abstract 1
- 230000001590 oxidative effect Effects 0.000 abstract 1
- 239000000825 pharmaceutical preparation Substances 0.000 abstract 1
- 229940125723 sedative agent Drugs 0.000 abstract 1
- 239000000932 sedative agent Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D243/00—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms
- C07D243/06—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4
- C07D243/10—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems
- C07D243/14—1,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines
- C07D243/16—1,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines substituted in position 5 by aryl radicals
- C07D243/18—1,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines substituted in position 5 by aryl radicals substituted in position 2 by nitrogen, oxygen or sulfur atoms
- C07D243/24—Oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C233/00—Carboxylic acid amides
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C247/00—Compounds containing azido groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C271/00—Derivatives of carbamic acids, i.e. compounds containing any of the groups, the nitrogen atom not being part of nitro or nitroso groups
- C07C271/06—Esters of carbamic acids
- C07C271/08—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms
- C07C271/10—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms with the nitrogen atoms of the carbamate groups bound to hydrogen atoms or to acyclic carbon atoms
- C07C271/22—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms with the nitrogen atoms of the carbamate groups bound to hydrogen atoms or to acyclic carbon atoms to carbon atoms of hydrocarbon radicals substituted by carboxyl groups
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Priority Applications (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IE209/73A IE34631B1 (en) | 1970-04-15 | 1970-06-30 | Benzophenone derivatives |
| IE208/73A IE34630B1 (en) | 1970-04-15 | 1970-06-30 | Benzophenone derivatives |
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US83867769A | 1969-07-02 | 1969-07-02 | |
| US87749069A | 1969-11-17 | 1969-11-17 | |
| US2893570A | 1970-04-15 | 1970-04-15 | |
| US3453270A | 1970-05-04 | 1970-05-04 | |
| US3702170A | 1970-05-13 | 1970-05-13 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| IE34629L IE34629L (en) | 1971-01-02 |
| IE34629B1 true IE34629B1 (en) | 1975-07-09 |
Family
ID=27534252
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IE851/70A IE34629B1 (en) | 1969-07-02 | 1970-06-30 | Benzodiazepine derivatives |
Country Status (13)
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| NL120864C (enrdf_load_stackoverflow) * | 1945-04-26 |
-
1970
- 1970-06-23 CH CH947370A patent/CH548404A/xx not_active IP Right Cessation
- 1970-06-29 SE SE7009007A patent/SE370700B/xx unknown
- 1970-06-29 IL IL34816A patent/IL34816A/en unknown
- 1970-06-30 IE IE851/70A patent/IE34629B1/xx unknown
- 1970-06-30 GB GB3150170A patent/GB1304707A/en not_active Expired
- 1970-06-30 DK DK339570AA patent/DK140282B/da unknown
- 1970-06-30 NO NO2573/70A patent/NO125930B/no unknown
- 1970-07-01 BE BE752832D patent/BE752832A/xx unknown
- 1970-07-01 FR FR7024337A patent/FR2059466B1/fr not_active Expired
- 1970-07-02 JP JP45058044A patent/JPS4833759B1/ja active Pending
- 1970-07-02 NL NL7009788A patent/NL7009788A/xx not_active Application Discontinuation
- 1970-07-02 DE DE19702032907 patent/DE2032907A1/de not_active Withdrawn
- 1970-07-02 HU HUHO1306A patent/HU164057B/hu unknown
Also Published As
| Publication number | Publication date |
|---|---|
| IL34816A0 (en) | 1970-08-19 |
| HU164057B (enrdf_load_stackoverflow) | 1973-12-28 |
| NO125930B (enrdf_load_stackoverflow) | 1972-11-27 |
| IE34629L (en) | 1971-01-02 |
| CH548404A (de) | 1974-04-30 |
| BE752832A (fr) | 1971-01-04 |
| JPS4833759B1 (enrdf_load_stackoverflow) | 1973-10-16 |
| FR2059466A1 (enrdf_load_stackoverflow) | 1971-06-04 |
| FR2059466B1 (enrdf_load_stackoverflow) | 1975-04-18 |
| NL7009788A (enrdf_load_stackoverflow) | 1971-01-05 |
| DK140282C (enrdf_load_stackoverflow) | 1979-12-17 |
| GB1304707A (enrdf_load_stackoverflow) | 1973-01-31 |
| DK140282B (da) | 1979-07-23 |
| DE2032907A1 (de) | 1971-01-07 |
| SE370700B (enrdf_load_stackoverflow) | 1974-10-28 |
| IL34816A (en) | 1973-08-29 |
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