IE33333B1 - Compositions for the treatment of depressive illness - Google Patents
Compositions for the treatment of depressive illnessInfo
- Publication number
- IE33333B1 IE33333B1 IE137469A IE137469A IE33333B1 IE 33333 B1 IE33333 B1 IE 33333B1 IE 137469 A IE137469 A IE 137469A IE 137469 A IE137469 A IE 137469A IE 33333 B1 IE33333 B1 IE 33333B1
- Authority
- IE
- Ireland
- Prior art keywords
- tryptophane
- laevorotatory
- compositions
- assimilation
- sugar
- Prior art date
Links
- 239000000203 mixture Substances 0.000 title abstract 3
- 208000020401 Depressive disease Diseases 0.000 title 1
- PEDCQBHIVMGVHV-UHFFFAOYSA-N Glycerine Chemical compound OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 abstract 6
- NGVDGCNFYWLIFO-UHFFFAOYSA-N pyridoxal 5'-phosphate Chemical compound CC1=NC=C(COP(O)(O)=O)C(C=O)=C1O NGVDGCNFYWLIFO-UHFFFAOYSA-N 0.000 abstract 4
- QIVBCDIJIAJPQS-VIFPVBQESA-N L-tryptophane Chemical compound C1=CC=C2C(C[C@H](N)C(O)=O)=CNC2=C1 QIVBCDIJIAJPQS-VIFPVBQESA-N 0.000 abstract 3
- QIVBCDIJIAJPQS-UHFFFAOYSA-N Tryptophan Natural products C1=CC=C2C(CC(N)C(O)=O)=CNC2=C1 QIVBCDIJIAJPQS-UHFFFAOYSA-N 0.000 abstract 3
- 239000006035 Tryptophane Substances 0.000 abstract 3
- 235000000346 sugar Nutrition 0.000 abstract 3
- 229960004799 tryptophan Drugs 0.000 abstract 3
- LDCYZAJDBXYCGN-VIFPVBQESA-N 5-hydroxy-L-tryptophan Chemical compound C1=C(O)C=C2C(C[C@H](N)C(O)=O)=CNC2=C1 LDCYZAJDBXYCGN-VIFPVBQESA-N 0.000 abstract 2
- CIWBSHSKHKDKBQ-JLAZNSOCSA-N Ascorbic acid Chemical compound OC[C@H](O)[C@H]1OC(=O)C(O)=C1O CIWBSHSKHKDKBQ-JLAZNSOCSA-N 0.000 abstract 2
- WQZGKKKJIJFFOK-GASJEMHNSA-N Glucose Natural products OC[C@H]1OC(O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-GASJEMHNSA-N 0.000 abstract 2
- RADKZDMFGJYCBB-UHFFFAOYSA-N Pyridoxal Chemical compound CC1=NC=C(CO)C(C=O)=C1O RADKZDMFGJYCBB-UHFFFAOYSA-N 0.000 abstract 2
- 125000003118 aryl group Chemical group 0.000 abstract 2
- WQZGKKKJIJFFOK-VFUOTHLCSA-N beta-D-glucose Chemical compound OC[C@H]1O[C@@H](O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-VFUOTHLCSA-N 0.000 abstract 2
- 239000003795 chemical substances by application Substances 0.000 abstract 2
- LDCYZAJDBXYCGN-UHFFFAOYSA-N oxitriptan Natural products C1=C(O)C=C2C(CC(N)C(O)=O)=CNC2=C1 LDCYZAJDBXYCGN-UHFFFAOYSA-N 0.000 abstract 2
- 235000007682 pyridoxal 5'-phosphate Nutrition 0.000 abstract 2
- 239000011589 pyridoxal 5'-phosphate Substances 0.000 abstract 2
- 229960001327 pyridoxal phosphate Drugs 0.000 abstract 2
- NHZMQXZHNVQTQA-UHFFFAOYSA-N pyridoxamine Chemical compound CC1=NC=C(CO)C(CN)=C1O NHZMQXZHNVQTQA-UHFFFAOYSA-N 0.000 abstract 2
- LXNHXLLTXMVWPM-UHFFFAOYSA-N pyridoxine Chemical compound CC1=NC=C(CO)C(CO)=C1O LXNHXLLTXMVWPM-UHFFFAOYSA-N 0.000 abstract 2
- HRZFUMHJMZEROT-UHFFFAOYSA-L sodium disulfite Chemical compound [Na+].[Na+].[O-]S(=O)S([O-])(=O)=O HRZFUMHJMZEROT-UHFFFAOYSA-L 0.000 abstract 2
- 239000004296 sodium metabisulphite Substances 0.000 abstract 2
- 235000010262 sodium metabisulphite Nutrition 0.000 abstract 2
- FBPFZTCFMRRESA-FSIIMWSLSA-N D-Glucitol Natural products OC[C@H](O)[C@H](O)[C@@H](O)[C@H](O)CO FBPFZTCFMRRESA-FSIIMWSLSA-N 0.000 abstract 1
- FBPFZTCFMRRESA-KVTDHHQDSA-N D-Mannitol Chemical compound OC[C@@H](O)[C@@H](O)[C@H](O)[C@H](O)CO FBPFZTCFMRRESA-KVTDHHQDSA-N 0.000 abstract 1
- FBPFZTCFMRRESA-JGWLITMVSA-N D-glucitol Chemical compound OC[C@H](O)[C@@H](O)[C@H](O)[C@H](O)CO FBPFZTCFMRRESA-JGWLITMVSA-N 0.000 abstract 1
- 229930195725 Mannitol Natural products 0.000 abstract 1
- 239000002253 acid Substances 0.000 abstract 1
- 239000002671 adjuvant Substances 0.000 abstract 1
- 230000001430 anti-depressive effect Effects 0.000 abstract 1
- 239000000935 antidepressant agent Substances 0.000 abstract 1
- 229940005513 antidepressants Drugs 0.000 abstract 1
- 239000007864 aqueous solution Substances 0.000 abstract 1
- 235000010323 ascorbic acid Nutrition 0.000 abstract 1
- 229960005070 ascorbic acid Drugs 0.000 abstract 1
- 239000011668 ascorbic acid Substances 0.000 abstract 1
- 239000002775 capsule Substances 0.000 abstract 1
- 238000006114 decarboxylation reaction Methods 0.000 abstract 1
- 239000008121 dextrose Substances 0.000 abstract 1
- 239000008103 glucose Substances 0.000 abstract 1
- 239000008187 granular material Substances 0.000 abstract 1
- 230000033444 hydroxylation Effects 0.000 abstract 1
- 238000005805 hydroxylation reaction Methods 0.000 abstract 1
- 235000020094 liqueur Nutrition 0.000 abstract 1
- 239000000594 mannitol Substances 0.000 abstract 1
- 235000010355 mannitol Nutrition 0.000 abstract 1
- 239000002243 precursor Substances 0.000 abstract 1
- 229960003581 pyridoxal Drugs 0.000 abstract 1
- 235000008164 pyridoxal Nutrition 0.000 abstract 1
- 239000011674 pyridoxal Substances 0.000 abstract 1
- 235000008151 pyridoxamine Nutrition 0.000 abstract 1
- 239000011699 pyridoxamine Substances 0.000 abstract 1
- 235000008160 pyridoxine Nutrition 0.000 abstract 1
- 239000011677 pyridoxine Substances 0.000 abstract 1
- WXMKPNITSTVMEF-UHFFFAOYSA-M sodium benzoate Chemical compound [Na+].[O-]C(=O)C1=CC=CC=C1 WXMKPNITSTVMEF-UHFFFAOYSA-M 0.000 abstract 1
- 235000010234 sodium benzoate Nutrition 0.000 abstract 1
- 239000004299 sodium benzoate Substances 0.000 abstract 1
- 229960002920 sorbitol Drugs 0.000 abstract 1
- 150000008163 sugars Chemical class 0.000 abstract 1
- UJMBCXLDXJUMFB-GLCFPVLVSA-K tartrazine Chemical compound [Na+].[Na+].[Na+].[O-]C(=O)C1=NN(C=2C=CC(=CC=2)S([O-])(=O)=O)C(=O)C1\N=N\C1=CC=C(S([O-])(=O)=O)C=C1 UJMBCXLDXJUMFB-GLCFPVLVSA-K 0.000 abstract 1
- 229960000943 tartrazine Drugs 0.000 abstract 1
- 235000012756 tartrazine Nutrition 0.000 abstract 1
- 239000004149 tartrazine Substances 0.000 abstract 1
- 229940011671 vitamin b6 Drugs 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Medicinal Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Molecular Biology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB4704268 | 1968-10-03 | ||
| GB266069 | 1969-01-16 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| IE33333L IE33333L (en) | 1970-04-03 |
| IE33333B1 true IE33333B1 (en) | 1974-05-29 |
Family
ID=26237645
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IE137469A IE33333B1 (en) | 1968-10-03 | 1969-10-03 | Compositions for the treatment of depressive illness |
Country Status (7)
| Country | Link |
|---|---|
| BE (1) | BE739613A (enExample) |
| CA (1) | CA934663A (enExample) |
| DE (1) | DE1949774A1 (enExample) |
| ES (1) | ES372150A1 (enExample) |
| FR (1) | FR2019845A1 (enExample) |
| IE (1) | IE33333B1 (enExample) |
| NL (1) | NL6914820A (enExample) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ATE14837T1 (de) * | 1981-10-05 | 1985-08-15 | Alec James Coppen | Pharmazeutische zusammensetzungen. |
| HU191598B (en) * | 1984-03-20 | 1987-03-30 | Egyt Gyogyszervegyeszeti Gyar | Method for the preparation of injection solution suitable preferably against cathosis |
| CA2410966C (en) * | 2002-11-01 | 2005-11-22 | Craig J. Hudson | Sexual desire and performance enhancement with protein-bound tryptophan |
-
1969
- 1969-09-30 BE BE739613D patent/BE739613A/xx unknown
- 1969-10-01 NL NL6914820A patent/NL6914820A/xx unknown
- 1969-10-02 DE DE19691949774 patent/DE1949774A1/de active Pending
- 1969-10-02 CA CA064057A patent/CA934663A/en not_active Expired
- 1969-10-03 FR FR6933840A patent/FR2019845A1/fr active Granted
- 1969-10-03 IE IE137469A patent/IE33333B1/xx unknown
- 1969-10-03 ES ES69372150A patent/ES372150A1/es not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| NL6914820A (enExample) | 1970-04-07 |
| DE1949774A1 (de) | 1970-05-27 |
| ES372150A1 (es) | 1971-12-16 |
| FR2019845A1 (en) | 1970-07-10 |
| FR2019845B1 (enExample) | 1973-01-12 |
| IE33333L (en) | 1970-04-03 |
| CA934663A (en) | 1973-10-02 |
| BE739613A (enExample) | 1970-03-02 |
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