IE33174B1 - Antibiotic 66-40 and methods for its production - Google Patents
Antibiotic 66-40 and methods for its productionInfo
- Publication number
- IE33174B1 IE33174B1 IE865/69A IE86569A IE33174B1 IE 33174 B1 IE33174 B1 IE 33174B1 IE 865/69 A IE865/69 A IE 865/69A IE 86569 A IE86569 A IE 86569A IE 33174 B1 IE33174 B1 IE 33174B1
- Authority
- IE
- Ireland
- Prior art keywords
- antibiotic
- mull
- condensation products
- aldehydes
- ketones
- Prior art date
Links
- URWAJWIAIPFPJE-YFMIWBNJSA-N sisomycin Chemical compound O1C[C@@](O)(C)[C@H](NC)[C@@H](O)[C@H]1O[C@@H]1[C@@H](O)[C@H](O[C@@H]2[C@@H](CC=C(CN)O2)N)[C@@H](N)C[C@H]1N URWAJWIAIPFPJE-YFMIWBNJSA-N 0.000 title abstract 5
- ZWEHNKRNPOVVGH-UHFFFAOYSA-N 2-Butanone Chemical compound CCC(C)=O ZWEHNKRNPOVVGH-UHFFFAOYSA-N 0.000 abstract 3
- CSCPPACGZOOCGX-UHFFFAOYSA-N Acetone Chemical compound CC(C)=O CSCPPACGZOOCGX-UHFFFAOYSA-N 0.000 abstract 3
- 150000001299 aldehydes Chemical class 0.000 abstract 3
- 239000007859 condensation product Substances 0.000 abstract 3
- 150000002576 ketones Chemical class 0.000 abstract 3
- KWOLFJPFCHCOCG-UHFFFAOYSA-N Acetophenone Chemical compound CC(=O)C1=CC=CC=C1 KWOLFJPFCHCOCG-UHFFFAOYSA-N 0.000 abstract 2
- RADKZDMFGJYCBB-UHFFFAOYSA-N Pyridoxal Chemical compound CC1=NC=C(CO)C(C=O)=C1O RADKZDMFGJYCBB-UHFFFAOYSA-N 0.000 abstract 2
- 238000010521 absorption reaction Methods 0.000 abstract 2
- 239000002253 acid Substances 0.000 abstract 2
- HUMNYLRZRPPJDN-UHFFFAOYSA-N benzaldehyde Chemical compound O=CC1=CC=CC=C1 HUMNYLRZRPPJDN-UHFFFAOYSA-N 0.000 abstract 2
- HYBBIBNJHNGZAN-UHFFFAOYSA-N furfural Chemical compound O=CC1=CC=CO1 HYBBIBNJHNGZAN-UHFFFAOYSA-N 0.000 abstract 2
- SMQUZDBALVYZAC-UHFFFAOYSA-N salicylaldehyde Chemical compound OC1=CC=CC=C1C=O SMQUZDBALVYZAC-UHFFFAOYSA-N 0.000 abstract 2
- 150000003839 salts Chemical class 0.000 abstract 2
- WJUFSDZVCOTFON-UHFFFAOYSA-N veratraldehyde Chemical compound COC1=CC=C(C=O)C=C1OC WJUFSDZVCOTFON-UHFFFAOYSA-N 0.000 abstract 2
- CEUXIAUEIGSQSZ-UHFFFAOYSA-N 2-cyclopentylacetaldehyde Chemical compound O=CCC1CCCC1 CEUXIAUEIGSQSZ-UHFFFAOYSA-N 0.000 abstract 1
- 241000894006 Bacteria Species 0.000 abstract 1
- 241000218919 Micromonospora inyonensis Species 0.000 abstract 1
- 241000606701 Rickettsia Species 0.000 abstract 1
- 239000002262 Schiff base Substances 0.000 abstract 1
- 150000004753 Schiff bases Chemical class 0.000 abstract 1
- IKHGUXGNUITLKF-XPULMUKRSA-N acetaldehyde Chemical compound [14CH]([14CH3])=O IKHGUXGNUITLKF-XPULMUKRSA-N 0.000 abstract 1
- 150000007513 acids Chemical class 0.000 abstract 1
- 230000003385 bacteriostatic effect Effects 0.000 abstract 1
- RWCCWEUUXYIKHB-UHFFFAOYSA-N benzophenone Chemical compound C=1C=CC=CC=1C(=O)C1=CC=CC=C1 RWCCWEUUXYIKHB-UHFFFAOYSA-N 0.000 abstract 1
- 239000012965 benzophenone Substances 0.000 abstract 1
- MLUCVPSAIODCQM-NSCUHMNNSA-N crotonaldehyde Chemical compound C\C=C\C=O MLUCVPSAIODCQM-NSCUHMNNSA-N 0.000 abstract 1
- MLUCVPSAIODCQM-UHFFFAOYSA-N crotonaldehyde Natural products CC=CC=O MLUCVPSAIODCQM-UHFFFAOYSA-N 0.000 abstract 1
- 239000003085 diluting agent Substances 0.000 abstract 1
- 239000003937 drug carrier Substances 0.000 abstract 1
- 238000000921 elemental analysis Methods 0.000 abstract 1
- 150000004677 hydrates Chemical class 0.000 abstract 1
- 230000008018 melting Effects 0.000 abstract 1
- 238000002844 melting Methods 0.000 abstract 1
- 229940032007 methylethyl ketone Drugs 0.000 abstract 1
- QNGNSVIICDLXHT-UHFFFAOYSA-N para-ethylbenzaldehyde Natural products CCC1=CC=C(C=O)C=C1 QNGNSVIICDLXHT-UHFFFAOYSA-N 0.000 abstract 1
- 238000007911 parenteral administration Methods 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 229960003581 pyridoxal Drugs 0.000 abstract 1
- 235000008164 pyridoxal Nutrition 0.000 abstract 1
- 239000011674 pyridoxal Substances 0.000 abstract 1
- 239000012453 solvate Substances 0.000 abstract 1
- 230000000699 topical effect Effects 0.000 abstract 1
- MWOOGOJBHIARFG-UHFFFAOYSA-N vanillin Chemical compound COC1=CC(C=O)=CC=C1O MWOOGOJBHIARFG-UHFFFAOYSA-N 0.000 abstract 1
- FGQOOHJZONJGDT-UHFFFAOYSA-N vanillin Natural products COC1=CC(O)=CC(C=O)=C1 FGQOOHJZONJGDT-UHFFFAOYSA-N 0.000 abstract 1
- 235000012141 vanillin Nutrition 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
- C07H15/20—Carbocyclic rings
- C07H15/22—Cyclohexane rings, substituted by nitrogen atoms
- C07H15/222—Cyclohexane rings substituted by at least two nitrogen atoms
- C07H15/226—Cyclohexane rings substituted by at least two nitrogen atoms with at least two saccharide radicals directly attached to the cyclohexane rings
- C07H15/234—Cyclohexane rings substituted by at least two nitrogen atoms with at least two saccharide radicals directly attached to the cyclohexane rings attached to non-adjacent ring carbon atoms of the cyclohexane rings, e.g. kanamycins, tobramycin, nebramycin, gentamicin A2
- C07H15/236—Cyclohexane rings substituted by at least two nitrogen atoms with at least two saccharide radicals directly attached to the cyclohexane rings attached to non-adjacent ring carbon atoms of the cyclohexane rings, e.g. kanamycins, tobramycin, nebramycin, gentamicin A2 a saccharide radical being substituted by an alkylamino radical in position 3 and by two substituents different from hydrogen in position 4, e.g. gentamicin complex, sisomicin, verdamycin
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Biotechnology (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Saccharide Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US74074268A | 1968-06-27 | 1968-06-27 | |
| US79730468A | 1968-12-16 | 1968-12-16 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| IE33174L IE33174L (en) | 1969-12-27 |
| IE33174B1 true IE33174B1 (en) | 1974-04-03 |
Family
ID=27113740
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IE865/69A IE33174B1 (en) | 1968-06-27 | 1969-06-24 | Antibiotic 66-40 and methods for its production |
Country Status (26)
| Country | Link |
|---|---|
| AT (2) | AT297929B (cs) |
| BE (1) | BE735145A (cs) |
| BG (1) | BG15881A3 (cs) |
| BR (1) | BR6910078D0 (cs) |
| CA (1) | CA931515A (cs) |
| CH (2) | CH529833A (cs) |
| CS (1) | CS149666B2 (cs) |
| CY (1) | CY817A (cs) |
| DE (1) | DE1932309C3 (cs) |
| DK (1) | DK126510B (cs) |
| ES (1) | ES368762A1 (cs) |
| FI (1) | FI46177C (cs) |
| FR (1) | FR2011732B1 (cs) |
| GB (1) | GB1274518A (cs) |
| IE (1) | IE33174B1 (cs) |
| IL (1) | IL32476A (cs) |
| IT (1) | IT1033250B (cs) |
| KE (1) | KE2540A (cs) |
| LU (1) | LU58942A1 (cs) |
| MY (1) | MY7500184A (cs) |
| NL (1) | NL155886B (cs) |
| NO (1) | NO129960B (cs) |
| OA (1) | OA04043A (cs) |
| RO (1) | RO57462A (cs) |
| SE (2) | SE376425B (cs) |
| YU (1) | YU34906B (cs) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4297486A (en) * | 1979-04-04 | 1981-10-27 | Toyo Jozo Kabushiki Kaisha | Aminoglycoside antibiotic G-367-1 and method for the production thereof |
| JPS5629598A (en) * | 1979-08-18 | 1981-03-24 | Toyo Jozo Co Ltd | Novel amino sugar antibiotic g-367-2 and its preparation |
-
1969
- 1969-06-24 IE IE865/69A patent/IE33174B1/xx unknown
- 1969-06-24 AT AT613570A patent/AT297929B/de not_active IP Right Cessation
- 1969-06-24 CH CH976669A patent/CH529833A/de not_active IP Right Cessation
- 1969-06-24 CH CH971771A patent/CH529743A/de not_active IP Right Cessation
- 1969-06-24 CY CY817A patent/CY817A/xx unknown
- 1969-06-24 BR BR210078/69A patent/BR6910078D0/pt unknown
- 1969-06-24 YU YU1616/69A patent/YU34906B/xx unknown
- 1969-06-24 IT IT18634/69A patent/IT1033250B/it active
- 1969-06-24 NL NL6909642.A patent/NL155886B/xx not_active IP Right Cessation
- 1969-06-24 AT AT597469A patent/AT299448B/de not_active IP Right Cessation
- 1969-06-24 SE SE7009228A patent/SE376425B/xx unknown
- 1969-06-24 FR FR696921096A patent/FR2011732B1/fr not_active Expired
- 1969-06-24 OA OA53648A patent/OA04043A/xx unknown
- 1969-06-24 LU LU58942D patent/LU58942A1/xx unknown
- 1969-06-24 NO NO02633/69A patent/NO129960B/no unknown
- 1969-06-24 IL IL32476A patent/IL32476A/en unknown
- 1969-06-24 FI FI691859A patent/FI46177C/fi active
- 1969-06-24 SE SE08942/69A patent/SE366560B/xx unknown
- 1969-06-24 GB GB31887/69A patent/GB1274518A/en not_active Expired
- 1969-06-24 CA CA055286A patent/CA931515A/en not_active Expired
- 1969-06-25 ES ES368762A patent/ES368762A1/es not_active Expired
- 1969-06-25 BE BE735145D patent/BE735145A/xx not_active IP Right Cessation
- 1969-06-25 DK DK343169AA patent/DK126510B/da not_active IP Right Cessation
- 1969-06-26 CS CS694518A patent/CS149666B2/cs unknown
- 1969-06-26 DE DE1932309A patent/DE1932309C3/de not_active Expired
- 1969-06-26 BG BG012532A patent/BG15881A3/bg unknown
- 1969-06-26 RO RO60355A patent/RO57462A/ro unknown
-
1975
- 1975-07-10 KE KE2540*UA patent/KE2540A/xx unknown
- 1975-12-30 MY MY1984/75A patent/MY7500184A/xx unknown
Also Published As
| Publication number | Publication date |
|---|---|
| BG15881A3 (bg) | 1972-04-12 |
| LU58942A1 (cs) | 1969-11-11 |
| DE1932309B2 (de) | 1974-06-20 |
| CA931515A (en) | 1973-08-07 |
| NL155886B (nl) | 1978-02-15 |
| RO57462A (cs) | 1974-12-15 |
| ES368762A1 (es) | 1971-04-01 |
| CY817A (en) | 1976-12-01 |
| CH529833A (de) | 1972-10-31 |
| FR2011732A1 (cs) | 1970-03-06 |
| AT297929B (de) | 1972-04-10 |
| BE735145A (cs) | 1969-12-29 |
| BR6910078D0 (pt) | 1973-02-08 |
| IL32476A0 (en) | 1969-08-27 |
| YU161669A (en) | 1979-10-31 |
| NO129960B (cs) | 1974-06-17 |
| DE1932309C3 (de) | 1975-02-20 |
| IT1033250B (it) | 1979-07-10 |
| MY7500184A (en) | 1975-12-31 |
| SE366560B (cs) | 1974-04-29 |
| IE33174L (en) | 1969-12-27 |
| IL32476A (en) | 1972-09-28 |
| KE2540A (en) | 1975-07-18 |
| CH529743A (de) | 1972-10-31 |
| GB1274518A (en) | 1972-05-17 |
| NL6909642A (cs) | 1969-12-30 |
| DE1932309A1 (de) | 1970-01-29 |
| AT299448B (de) | 1972-06-26 |
| YU34906B (en) | 1980-04-30 |
| DK126510B (da) | 1973-07-23 |
| CS149666B2 (en) | 1973-07-25 |
| SE376425B (cs) | 1975-05-26 |
| OA04043A (fr) | 1979-10-15 |
| FI46177C (fi) | 1973-01-10 |
| FI46177B (cs) | 1972-10-02 |
| FR2011732B1 (cs) | 1973-01-12 |
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