IE33157B1 - New hypocalcaemic peptides and process for their manufacture - Google Patents
New hypocalcaemic peptides and process for their manufactureInfo
- Publication number
- IE33157B1 IE33157B1 IE790/69A IE79069A IE33157B1 IE 33157 B1 IE33157 B1 IE 33157B1 IE 790/69 A IE790/69 A IE 790/69A IE 79069 A IE79069 A IE 79069A IE 33157 B1 IE33157 B1 IE 33157B1
- Authority
- IE
- Ireland
- Prior art keywords
- june
- extract
- system containing
- hypocalcaemic
- peptides
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/575—Hormones
- C07K14/585—Calcitonins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/22—Hormones
- A61K38/23—Calcitonins
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Endocrinology (AREA)
- Organic Chemistry (AREA)
- Zoology (AREA)
- Gastroenterology & Hepatology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- General Health & Medical Sciences (AREA)
- Molecular Biology (AREA)
- Immunology (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Toxicology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Genetics & Genomics (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
Abstract
1,270,595. Human calcitonin. CIBA-GIEGY A.G. 20 June, 1969 [20 June, 1968; 21 June, 1968; 12 July, 1968; 27 Aug., 1968; 6 Sept., 1968], No. 31286/69. Heading A5B. [Also in Division C2] In a process for extracting human calcitonin, defatted medula carcinoma of the thyroid gland or C-cell metastasis material is first purified with alcohol a dilute trichloracetic acid then treated one or more times with a solvent system containing water and a 1-5C-alkanol, especially a system containing HOAc and BuOH, at pH 1-6 and subjecting the extract to gel chromatography using formic acid as eluant. The extract is further separated by countercurrent distribution into HT-C 1 , HT-C 2 , HT-C 11 and HT-C 21 components. The component HT-C 21 is of unknown constitution. HT-C 2 and H-T-C 11 are dotriacontapepticles of known constitution and HT-C 1 is a dimer of HT-C 2 (see C2).
[GB1270595A]
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CH933368 | 1968-06-20 | ||
| CH933768 | 1968-06-21 | ||
| CH1045468 | 1968-07-12 | ||
| CH1281068 | 1968-08-27 | ||
| CH1340868 | 1968-09-06 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| IE33157L IE33157L (en) | 1969-12-20 |
| IE33157B1 true IE33157B1 (en) | 1974-04-03 |
Family
ID=27509374
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IE790/69A IE33157B1 (en) | 1968-06-20 | 1969-06-10 | New hypocalcaemic peptides and process for their manufacture |
Country Status (10)
| Country | Link |
|---|---|
| BE (1) | BE734868A (en) |
| CA (1) | CA919591A (en) |
| DE (1) | DE1929957C3 (en) |
| FR (1) | FR2011262A1 (en) |
| GB (1) | GB1270595A (en) |
| IE (1) | IE33157B1 (en) |
| IL (1) | IL32360A (en) |
| MY (1) | MY7400315A (en) |
| NL (1) | NL162365C (en) |
| PH (1) | PH13930A (en) |
-
1969
- 1969-05-22 FR FR6916731A patent/FR2011262A1/fr active Pending
- 1969-06-08 IL IL32360A patent/IL32360A/en unknown
- 1969-06-10 IE IE790/69A patent/IE33157B1/en unknown
- 1969-06-11 CA CA054016A patent/CA919591A/en not_active Expired
- 1969-06-12 DE DE1929957A patent/DE1929957C3/en not_active Expired
- 1969-06-17 PH PH10448A patent/PH13930A/en unknown
- 1969-06-19 NL NL6909396.A patent/NL162365C/en not_active IP Right Cessation
- 1969-06-19 BE BE734868D patent/BE734868A/xx not_active IP Right Cessation
- 1969-06-20 GB GB31286/69A patent/GB1270595A/en not_active Expired
-
1974
- 1974-12-30 MY MY315/74A patent/MY7400315A/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| DE1929957B2 (en) | 1980-04-03 |
| DE1929957A1 (en) | 1970-01-02 |
| BE734868A (en) | 1969-12-19 |
| CA919591A (en) | 1973-01-23 |
| NL6909396A (en) | 1969-12-23 |
| DE1929957C3 (en) | 1980-11-27 |
| IL32360A0 (en) | 1969-08-27 |
| NL162365C (en) | 1980-05-16 |
| IE33157L (en) | 1969-12-20 |
| NL162365B (en) | 1979-12-17 |
| PH13930A (en) | 1980-11-04 |
| MY7400315A (en) | 1974-12-31 |
| FR2011262A1 (en) | 1970-02-27 |
| GB1270595A (en) | 1972-04-12 |
| IL32360A (en) | 1973-11-28 |
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