IE32708B1 - Sydnonimine derivatives - Google Patents

Sydnonimine derivatives

Info

Publication number
IE32708B1
IE32708B1 IE400/69A IE40069A IE32708B1 IE 32708 B1 IE32708 B1 IE 32708B1 IE 400/69 A IE400/69 A IE 400/69A IE 40069 A IE40069 A IE 40069A IE 32708 B1 IE32708 B1 IE 32708B1
Authority
IE
Ireland
Prior art keywords
heterocyclic ring
substituted
cycloalkyl
march
halogen
Prior art date
Application number
IE400/69A
Other versions
IE32708L (en
Original Assignee
Boehringer Sohn Ingelheim
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boehringer Sohn Ingelheim filed Critical Boehringer Sohn Ingelheim
Publication of IE32708L publication Critical patent/IE32708L/en
Publication of IE32708B1 publication Critical patent/IE32708B1/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D271/00—Heterocyclic compounds containing five-membered rings having two nitrogen atoms and one oxygen atom as the only ring hetero atoms
    • C07D271/02—Heterocyclic compounds containing five-membered rings having two nitrogen atoms and one oxygen atom as the only ring hetero atoms not condensed with other rings
    • C07D271/04—1,2,3-Oxadiazoles; Hydrogenated 1,2,3-oxadiazoles
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

1,219,254. Sydnonimine derivatives. BOEHRINGER INGELHEIM G.m.b.H. 26 March, 1969 [26 March, 1968], No. 15910/69. Heading C2C Compounds of the general formula (R 1 , 2 = alkyl, cycloalkyl, aralkyl optionally substituted by CH 3 or halogen, heterocyclic ring linked via alkylene chain to N, or -NR 1 R 2 = heterocyclic ring optionally containing more than one heteroatom and/or being substituted by CH 3 ; R 3 = H, -COR 4 (R4 = alkyl, cycloalkyl, Ph, halophenyl, alkoxy, unsubstituted or substituted nitrogen-containing heterocyclic ring); Hal = halogen) and their acid addition salts are prepared by halogenating a compound of the formula or an acid addition salt thereof, optionally followed by deacylation and/or salt formation. The preparation of the starting materials by standard methods is described. The above compounds are hypotensive agents, and the salts may be administered in the form of pharmaceutical preparations containing them in association with a carrier. [GB1219254A]
IE400/69A 1968-03-26 1969-03-25 Sydnonimine derivatives IE32708B1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19681770061 DE1770061A1 (en) 1968-03-26 1968-03-26 New substituted 3-amino-4-bromosydnomimines

Publications (2)

Publication Number Publication Date
IE32708L IE32708L (en) 1969-09-26
IE32708B1 true IE32708B1 (en) 1973-10-31

Family

ID=5700383

Family Applications (1)

Application Number Title Priority Date Filing Date
IE400/69A IE32708B1 (en) 1968-03-26 1969-03-25 Sydnonimine derivatives

Country Status (18)

Country Link
AT (1) AT285619B (en)
BE (1) BE730510A (en)
BG (1) BG15220A3 (en)
BR (1) BR6907417D0 (en)
CA (1) CA945990A (en)
CH (1) CH519511A (en)
DE (1) DE1770061A1 (en)
DK (1) DK130296B (en)
ES (2) ES364979A1 (en)
FI (1) FI54480C (en)
FR (1) FR2004770A1 (en)
GB (1) GB1219254A (en)
HU (1) HU162735B (en)
IE (1) IE32708B1 (en)
IL (1) IL31909A (en)
NL (1) NL6904632A (en)
SE (1) SE374746B (en)
YU (1) YU69369A (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2930736A1 (en) * 1979-07-28 1981-02-12 Cassella Ag PHARMACOLOGICALLY ACTIVE, SUBSTITUTED 3-AMINO-SYDNONIMINE, METHOD FOR THE PRODUCTION THEREOF AND THEIR USE

Also Published As

Publication number Publication date
ES364979A1 (en) 1971-02-16
YU69369A (en) 1978-09-18
BE730510A (en) 1969-09-26
NL6904632A (en) 1969-09-30
DK130296C (en) 1975-06-30
BG15220A3 (en) 1975-11-21
FI54480C (en) 1978-12-11
DK130296B (en) 1975-02-03
AT285619B (en) 1970-11-10
FI54480B (en) 1978-08-31
IL31909A (en) 1973-01-30
FR2004770A1 (en) 1969-11-28
ES376981A1 (en) 1972-05-01
HU162735B (en) 1973-04-28
CA945990A (en) 1974-04-23
IE32708L (en) 1969-09-26
GB1219254A (en) 1971-01-13
SE374746B (en) 1975-03-17
BR6907417D0 (en) 1973-04-12
IL31909A0 (en) 1969-05-28
CH519511A (en) 1972-02-29
DE1770061A1 (en) 1971-09-16

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