ID27774A - Turunan-turunan imidazol dengan substitusi bifenilsulfonil, metoda pembuatannya dan penggunaannya sebagai obat atau zat diagnostik - Google Patents

Turunan-turunan imidazol dengan substitusi bifenilsulfonil, metoda pembuatannya dan penggunaannya sebagai obat atau zat diagnostik

Info

Publication number
ID27774A
ID27774A IDW20010129A ID20010129A ID27774A ID 27774 A ID27774 A ID 27774A ID W20010129 A IDW20010129 A ID W20010129A ID 20010129 A ID20010129 A ID 20010129A ID 27774 A ID27774 A ID 27774A
Authority
ID
Indonesia
Prior art keywords
substitution
bifenilsulfonil
drivings
imidazol
diagnostic
Prior art date
Application number
IDW20010129A
Other languages
English (en)
Indonesian (id)
Inventor
Heinz-Werner Dr Kleemann
Hans Jochen Dr Lang
Jan-Robert Dr Schwark
Stefan Dr Petry
Andreas Dr Weichert
Original Assignee
Aventis Pharma Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Aventis Pharma Gmbh filed Critical Aventis Pharma Gmbh
Publication of ID27774A publication Critical patent/ID27774A/id

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/64—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms, e.g. histidine
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/66—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D233/70—One oxygen atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/4164—1,3-Diazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/06—Antiarrhythmics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/66—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D233/68—Halogen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/66—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D233/88—Nitrogen atoms, e.g. allantoin
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/66—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D233/90—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/66—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D233/91—Nitro radicals

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
IDW20010129A 1998-07-18 1999-07-10 Turunan-turunan imidazol dengan substitusi bifenilsulfonil, metoda pembuatannya dan penggunaannya sebagai obat atau zat diagnostik ID27774A (id)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19832428A DE19832428A1 (de) 1998-07-18 1998-07-18 Imidazolderivate mit Biphenylsulfonylsubstitution, Verfahren zu ihrer Herstellung, ihre Verwendung als Medikament oder Diagnostikum sowie sie enthaltendes Medikament

Publications (1)

Publication Number Publication Date
ID27774A true ID27774A (id) 2001-04-26

Family

ID=7874574

Family Applications (1)

Application Number Title Priority Date Filing Date
IDW20010129A ID27774A (id) 1998-07-18 1999-07-10 Turunan-turunan imidazol dengan substitusi bifenilsulfonil, metoda pembuatannya dan penggunaannya sebagai obat atau zat diagnostik

Country Status (19)

Country Link
US (1) US6369236B1 (fr)
EP (1) EP1097141B1 (fr)
JP (1) JP4567885B2 (fr)
KR (1) KR20010071957A (fr)
CN (1) CN1211370C (fr)
AR (1) AR019405A1 (fr)
AT (1) ATE362920T1 (fr)
AU (1) AU764438B2 (fr)
BR (1) BR9912241A (fr)
CA (1) CA2338059A1 (fr)
DE (2) DE19832428A1 (fr)
HK (1) HK1038743A1 (fr)
HU (1) HUP0102607A3 (fr)
ID (1) ID27774A (fr)
PL (1) PL345585A1 (fr)
RU (1) RU2246488C2 (fr)
TR (1) TR200100134T2 (fr)
WO (1) WO2000003996A1 (fr)
ZA (1) ZA200100278B (fr)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE19832428A1 (de) 1998-07-18 2000-01-20 Hoechst Marion Roussel De Gmbh Imidazolderivate mit Biphenylsulfonylsubstitution, Verfahren zu ihrer Herstellung, ihre Verwendung als Medikament oder Diagnostikum sowie sie enthaltendes Medikament
DE19832429A1 (de) 1998-07-18 2000-01-20 Hoechst Marion Roussel De Gmbh Imidazolderivate mit Biphenylsulfonylsubstitution, Verfahren zu ihrer Herstellung, ihre Verwendung als Medikament oder Diagnostikum sowie sie enthaltendes Medikament
DE10206354A1 (de) * 2002-02-14 2003-08-28 Aventis Pharma Gmbh Verwendung von Inhibitoren des Natrium-abhängigen Chlorid-Bicarbonat-Austauschers zur Behandlung von thrombotischen und inflammatorischer Erkrankungen
US20030220383A1 (en) * 2002-02-14 2003-11-27 Aventis Pharma Deutschland Gmbh Use of inhibitors of the sodium-dependent chloride/bicarbonate exchanger for the treatment of thrombotic and inflammatory disorders
CA2691662A1 (fr) 2007-07-02 2009-01-08 F. Hoffmann-La Roche Ag Derives imidazoles comme antagonistes du recepteur ccr2
US8236843B2 (en) 2008-09-02 2012-08-07 Elder Pharmaceuticals Ltd. Anti inflammatory compounds
KR101044953B1 (ko) * 2009-01-07 2011-06-29 (주) 인우 코퍼레이션 이중분사노즐을 이용한 악취제거 시스템
SG11201610815PA (en) * 2014-06-23 2017-02-27 Nissan Chemical Ind Ltd Method for producing silane compound having sulfonyl bond
WO2018002673A1 (fr) 2016-07-01 2018-01-04 N4 Pharma Uk Limited Nouvelles formulations d'antagonistes du récepteur de l'angiotensine ii

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5126342A (en) * 1990-10-01 1992-06-30 Merck & Co., Inc. Imidazole angiotensin ii antagonists incorporating acidic functional groups
CA2058198A1 (fr) * 1991-01-04 1992-07-05 Adalbert Wagner Procede de preparation et utilisation de derives d'azole
JP3290657B2 (ja) * 1991-05-01 2002-06-10 メルク エンド カムパニー インコーポレーテッド アンギオテンシンｉｉ拮抗剤として活性な酸性アラルキルトリアゾール誘導体
TW215434B (fr) * 1992-03-07 1993-11-01 Hoechst Ag
US5310929A (en) * 1992-08-06 1994-05-10 E. I. Du Pont De Nemours And Company Prodrugs of imidazole carboxylic acids as angiotensin II receptor antagonists
FR2711367B1 (fr) * 1993-10-19 1995-12-01 Roussel Uclaf Nouveau procédé de préparation de dérivés soufrés de l'imidazole et les nouveaux intermédiaires obtenus.
FR2711368B1 (fr) * 1993-09-16 1996-01-05 Roussel Uclaf Nouveau procédé de préparation de dérivés soufrés de l'imidazole et les nouveaux intermédiaires obtenus.
FR2716883B1 (fr) * 1994-03-04 1996-04-26 Roussel Uclaf Nouveaux dérivés tétrasubstitués de l'imidazole, leur préparation, nouveaux intermédiaires obtenus, leur application à titre de médicaments, compositions pharmaceutiques les renfermant.
FR2716882B1 (fr) 1994-03-04 1996-04-05 Roussel Uclaf Utilisation de dérivés de l'imidazole au traitement d'affections impliquant les récepteurs AT1 et AT2 de l'Angiotensine, certains de ces produits, leur préparation, compositions pharmaceutiques.
DE19540995A1 (de) * 1995-11-03 1997-05-07 Hoechst Ag Substituierte Sulfonimidamide, Verfahren zu ihrer Herstellung, ihre Verwendung als Medikament oder Diagnostikum sowie sie enthaltendes Medikament
EP0855392A3 (fr) * 1997-01-22 2000-01-05 Hoechst Aktiengesellschaft Hétérocycles à cinq chaínons contenant des substituants biphénylylsulphoniques, leur procédé de préparation, leur utilisation comme médicament ou agent diagnostique ainsi que médicament les contenant
DE19832428A1 (de) 1998-07-18 2000-01-20 Hoechst Marion Roussel De Gmbh Imidazolderivate mit Biphenylsulfonylsubstitution, Verfahren zu ihrer Herstellung, ihre Verwendung als Medikament oder Diagnostikum sowie sie enthaltendes Medikament
DE19832429A1 (de) 1998-07-18 2000-01-20 Hoechst Marion Roussel De Gmbh Imidazolderivate mit Biphenylsulfonylsubstitution, Verfahren zu ihrer Herstellung, ihre Verwendung als Medikament oder Diagnostikum sowie sie enthaltendes Medikament

Also Published As

Publication number Publication date
DE19832428A1 (de) 2000-01-20
EP1097141A1 (fr) 2001-05-09
HK1038743A1 (en) 2002-03-28
PL345585A1 (en) 2001-12-17
CA2338059A1 (fr) 2000-01-27
AR019405A1 (es) 2002-02-20
DE59914347D1 (de) 2007-07-05
EP1097141B1 (fr) 2007-05-23
AU5280799A (en) 2000-02-07
CN1211370C (zh) 2005-07-20
AU764438B2 (en) 2003-08-21
HUP0102607A2 (hu) 2002-03-28
CN1309645A (zh) 2001-08-22
US6369236B1 (en) 2002-04-09
ZA200100278B (en) 2001-08-06
KR20010071957A (ko) 2001-07-31
JP4567885B2 (ja) 2010-10-20
BR9912241A (pt) 2001-04-10
HUP0102607A3 (en) 2002-05-28
TR200100134T2 (tr) 2001-07-23
RU2246488C2 (ru) 2005-02-20
ATE362920T1 (de) 2007-06-15
JP2002520399A (ja) 2002-07-09
WO2000003996A1 (fr) 2000-01-27

Similar Documents

Publication Publication Date Title
DE3674815D1 (de) Waessriges haftgel und verfahren zu seiner herstellung.
DE3780226D1 (de) Neue pharmazeutische praeparate zur topischen applikation, verfahren zu ihrer herstellung und ihre verwendung.
EE9700044A (et) Heteroarüüloksasolidinoonid, nende valmistamismeetod, kasutamine ravimite valmistamiseks ja nimetatud ühendeid sisaldavad ravimid.
DE3687646D1 (de) Biosensor und dessen herstellung.
DE69627709D1 (de) N-(unsubstituierte oder substituierte)-4-substituierte-6-(unsubstituierte oder substituierte)phenoxy-2-pyridincarboxamide oder -thiocarboxamide, verfahren zu deren herstellung sowie herbizide
DE69131627D1 (de) Dialkoxypyridinylbenzimidazolderivate, verfahren zur herstellung und ihre pharmazeutische verwendung
ID30116A (id) Turunan-turunan piridopiranoazepin, pembuatannya dan penggunaan terapinya
DE68905161D1 (de) Den blutcholesterinspiegel senkende arzneimittel.
DE59905572D1 (de) Substituierte 4-amino-2-aryl-pyrimidine, ihre herstellung, ihre verwendung und sie enthaltende pharmazeutische präparate
DE50004150D1 (de) Polymorphe von telmisartan, verfahren zu deren herstellung und deren verwendung zur herstellung eines arzneimittels
ID19574A (id) Lingkar-lingkar aneka beranggota-5 yang mempunyai substitusi bifenilsulfonil, proses pembuatannya penggunaannya sebagai obat atau diagnosa dan obat yang terdiri dari zat-zat itu
ATE124482T1 (de) Zellulosefaser-aggregat und verfahren zu dessen herstellung.
ID27774A (id) Turunan-turunan imidazol dengan substitusi bifenilsulfonil, metoda pembuatannya dan penggunaannya sebagai obat atau zat diagnostik
NO306156B1 (no) Substituerte benzyloksykarbonylguanidiner, deres anvendelse til fremstilling av medikament eller diagnostikum sÕvel som legemidler inneholdende disse
NO305948B1 (no) Basisk substituerte benzolguanidiner, deres anvendelse til fremstilling av medikament eller diagnostikum samt medikament inneholdende forbindelsen
EE9700065A (et) Uus keemiline ühend, selle valmistamine ja kasutamine ravimina
EE05187B1 (et) Hirudiini prekursor, selle kasutamine ja meetod Leu-hirudiini valmistamiseks
ID16989A (id) 2-naftoilguanidin tersubstitusi, proses untuk pembuatannya, pemakaiannya sebagai obat atau diagnostik, dan obat yang mengandungnya
DE69621521D1 (de) Cyclodextrinderivate, ihre Herstellung und Verwendung zur Einbringung von hydrophoben Molekülen in strukturierten Tensidsystemen
DE69822711D1 (de) Verfarhen zur Herstellung von Dialkylnaphthalinen
ID20967A (id) Kroman tersubstitusi sulfonamida, proses pembuatannya, penggunaannya sebagai obat, dan sediaan farmasi yang mengandung bahan tersebut
ID17038A (id) Orto-benzoilguanidin tersubstitusi, proses untuk pembuatannya, pemakaiannya sebagai obat atau diagnostik, dan obat yang mengandungnya
ID27023A (id) Turunan imidazola bersubstitusi bifenilsulfonil, proses penyiapannya, penggunaannya sebagai obat atau zat diagnosa dan obat yang mengandungnya
ITRM930818A0 (it) Procedimento per la produzione in piante di anticorpi ingegnerizzati, anticorpi prodotti e loro uso in diagnosi e terapia.
DE3774615D1 (de) Packungsstruktur und verfahren zu dessen herstellung.