HUT71919A - Process for preparing 2,2-difluoroketene silyl o,s-acetals and alpha, alpha-difluoro-beta-silyloxy-1,3-dioxolane-4-propanoic acid o,s-esters - Google Patents

Process for preparing 2,2-difluoroketene silyl o,s-acetals and alpha, alpha-difluoro-beta-silyloxy-1,3-dioxolane-4-propanoic acid o,s-esters

Info

Publication number
HUT71919A
HUT71919A HU9501061A HU9501061A HUT71919A HU T71919 A HUT71919 A HU T71919A HU 9501061 A HU9501061 A HU 9501061A HU 9501061 A HU9501061 A HU 9501061A HU T71919 A HUT71919 A HU T71919A
Authority
HU
Hungary
Prior art keywords
alpha
silyloxy
acetals
dioxolane
difluoro
Prior art date
Application number
HU9501061A
Other languages
English (en)
Other versions
HU218118B (hu
HU9501061D0 (en
Inventor
John Ashley Weigel
Original Assignee
Lilly Co Eli
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lilly Co Eli filed Critical Lilly Co Eli
Publication of HU9501061D0 publication Critical patent/HU9501061D0/hu
Publication of HUT71919A publication Critical patent/HUT71919A/hu
Publication of HU218118B publication Critical patent/HU218118B/hu

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F7/00Compounds containing elements of Groups 4 or 14 of the Periodic Table
    • C07F7/02Silicon compounds
    • C07F7/08Compounds having one or more C—Si linkages
    • C07F7/18Compounds having one or more C—Si linkages as well as one or more C—O—Si linkages
    • C07F7/1804Compounds having Si-O-C linkages
    • C07F7/1872Preparation; Treatments not provided for in C07F7/20
    • C07F7/188Preparation; Treatments not provided for in C07F7/20 by reactions involving the formation of Si-O linkages
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F7/00Compounds containing elements of Groups 4 or 14 of the Periodic Table
    • C07F7/02Silicon compounds
    • C07F7/08Compounds having one or more C—Si linkages
    • C07F7/18Compounds having one or more C—Si linkages as well as one or more C—O—Si linkages
    • C07F7/1804Compounds having Si-O-C linkages
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F7/00Compounds containing elements of Groups 4 or 14 of the Periodic Table
    • C07F7/02Silicon compounds
    • C07F7/08Compounds having one or more C—Si linkages
    • C07F7/18Compounds having one or more C—Si linkages as well as one or more C—O—Si linkages
    • C07F7/1804Compounds having Si-O-C linkages
    • C07F7/1872Preparation; Treatments not provided for in C07F7/20
    • C07F7/1892Preparation; Treatments not provided for in C07F7/20 by reactions not provided for in C07F7/1876 - C07F7/1888

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
HU9501061A 1994-04-14 1995-04-12 Eljárás 2,2-difluorketén-szilil-O,S-acetálok és alfa, alfa-difluor-béta-szilil-oxi-1,3-dioxolán-4-propánsav-O,S-észterek előállítására HU218118B (hu)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US08/227,820 US5428176A (en) 1994-04-14 1994-04-14 Process for preparing 2,2-difluoroketene silyl O,S-acetals and α,α-difluoro-β-silyloxy-1,3-dioxolane-4-propanoic acid O,S-esters

Publications (3)

Publication Number Publication Date
HU9501061D0 HU9501061D0 (en) 1995-06-28
HUT71919A true HUT71919A (en) 1996-02-28
HU218118B HU218118B (hu) 2000-06-28

Family

ID=22854602

Family Applications (1)

Application Number Title Priority Date Filing Date
HU9501061A HU218118B (hu) 1994-04-14 1995-04-12 Eljárás 2,2-difluorketén-szilil-O,S-acetálok és alfa, alfa-difluor-béta-szilil-oxi-1,3-dioxolán-4-propánsav-O,S-észterek előállítására

Country Status (11)

Country Link
US (1) US5428176A (hu)
EP (3) EP0970962A3 (hu)
JP (1) JPH07285973A (hu)
KR (1) KR950032237A (hu)
BR (1) BR9501546A (hu)
CA (1) CA2146942A1 (hu)
ES (1) ES2166800T3 (hu)
FI (1) FI951759A (hu)
HU (1) HU218118B (hu)
IL (1) IL113357A (hu)
TW (1) TW317567B (hu)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR0148439B1 (ko) * 1994-03-11 1998-11-02 마사까쓰 마쓰모또 1,2-디옥세탄 유도체
US6001994A (en) * 1995-12-13 1999-12-14 Eli Lilly And Company Process for making gemcitabine hydrochloride
US5756775A (en) * 1995-12-13 1998-05-26 Eli Lilly And Company Process to make α,α-difluoro-β-hydroxyl thiol esters
EP0779275A2 (en) 1995-12-13 1997-06-18 Eli Lilly And Company Alpha, Alpha - Difluoro-beta -hydroxy thiol esters and their synthesis
USPP12237P2 (en) 1999-06-01 2001-11-27 Florfis Ag Geranium plant named ‘Fisrocky Dark Red’
WO2001000634A1 (en) 1999-06-29 2001-01-04 Wright Chemical Corporation Synthesis of vinyl carbonates for use in producing vinyl carbamates
DE10335061B4 (de) * 2003-07-31 2005-11-17 Wacker-Chemie Gmbh Verfahren zur Herstellung von OH-geschützten [4-(2,6-damino-9H-purin-9-yl)-1,3-dioxolan-2-yl]methanol-Derivaten
KR100578616B1 (ko) * 2004-07-23 2006-05-10 한미약품 주식회사 D-에리트로-2,2-다이플루오로-2-데옥시-1-옥소라이보스화합물의 제조방법

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4508880A (en) * 1981-06-30 1985-04-02 E. I. Du Pont De Nemours And Company "Living" polymers and process for their preparation
US4417034A (en) * 1981-06-30 1983-11-22 E. I. Du Pont De Nemours & Co. Living polymers and process for their preparation
US4414372A (en) * 1982-06-17 1983-11-08 E. I. Du Pont De Nemours & Co. Process for preparing living polymers
US4526988A (en) * 1983-03-10 1985-07-02 Eli Lilly And Company Difluoro antivirals and intermediate therefor
US4482729A (en) * 1984-03-04 1984-11-13 Daikin Kogyo Co., Ltd. Fluoroalkyl silyl ketene acetals and a process for preparing the same
US4780554A (en) * 1984-11-20 1988-10-25 Union Carbide Corporation O-silylated ketene acetals and enol ethers and method of preparation
US4754046A (en) * 1987-06-25 1988-06-28 Dow Corning Corporation Stabilized silyl ketene acetals
US4824981A (en) * 1987-07-06 1989-04-25 Dow Corning Corporation Process to produce silyl ketene acetals
US4746750A (en) * 1987-08-31 1988-05-24 Dow Corning Corporation Synthesis of silyl ketene acetal from allyl 2-organoacrylates
US4824980A (en) * 1988-09-02 1989-04-25 Dow Corning Corporation Process to produce O-silyl O,N-ketene acetals
JPH0267250A (ja) * 1988-09-02 1990-03-07 Asahi Glass Co Ltd 2,2‐ジフルオロ‐3‐ヒドロキシカルボン酸誘導体の製造法
KR900012940A (ko) * 1989-02-14 1990-09-03 사와무라 하루오 유기규소 화합물의 제조방법
JPH02270841A (ja) * 1989-04-12 1990-11-05 Asahi Glass Co Ltd 2,2―ジフルオロ―3,4,5―トリヒドロキシカルボン酸誘導体の製造法

Also Published As

Publication number Publication date
EP1258486A3 (en) 2004-01-07
ES2166800T3 (es) 2002-05-01
CA2146942A1 (en) 1995-10-15
JPH07285973A (ja) 1995-10-31
FI951759A (fi) 1995-10-15
IL113357A (en) 2000-10-31
EP0970962A3 (en) 2001-04-11
KR950032237A (ko) 1995-12-20
HU218118B (hu) 2000-06-28
HU9501061D0 (en) 1995-06-28
EP1258486A2 (en) 2002-11-20
US5428176A (en) 1995-06-27
BR9501546A (pt) 1995-11-14
TW317567B (hu) 1997-10-11
FI951759A0 (fi) 1995-04-12
EP0677527A1 (en) 1995-10-18
EP0970962A2 (en) 2000-01-12
IL113357A0 (en) 1995-07-31
EP0677527B1 (en) 2002-01-16

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Legal Events

Date Code Title Description
HMM4 Cancellation of final prot. due to non-payment of fee