HUT65983A - Process for the production of imidazole-condensed-compounds and pharmaceutical compositions containing them - Google Patents

Process for the production of imidazole-condensed-compounds and pharmaceutical compositions containing them

Info

Publication number
HUT65983A
HUT65983A HU9300390A HU39093A HUT65983A HU T65983 A HUT65983 A HU T65983A HU 9300390 A HU9300390 A HU 9300390A HU 39093 A HU39093 A HU 39093A HU T65983 A HUT65983 A HU T65983A
Authority
HU
Hungary
Prior art keywords
compounds
imidazole
condensed
production
pharmaceutical compositions
Prior art date
Application number
HU9300390A
Other languages
English (en)
Other versions
HU9300390D0 (en
Inventor
Mark Whittaker
Andrew Miller
Original Assignee
British Bio Technology
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB909017878A external-priority patent/GB9017878D0/en
Priority claimed from GB909018040A external-priority patent/GB9018040D0/en
Priority claimed from GB919112857A external-priority patent/GB9112857D0/en
Application filed by British Bio Technology filed Critical British Bio Technology
Publication of HU9300390D0 publication Critical patent/HU9300390D0/hu
Publication of HUT65983A publication Critical patent/HUT65983A/hu

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D235/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
    • C07D235/02—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
    • C07D235/04—Benzimidazoles; Hydrogenated benzimidazoles
    • C07D235/06—Benzimidazoles; Hydrogenated benzimidazoles with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 2
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/415—1,2-Diazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/02—Non-specific cardiovascular stimulants, e.g. drugs for syncope, antihypotensives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D235/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
    • C07D235/02—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
    • C07D235/04—Benzimidazoles; Hydrogenated benzimidazoles
    • C07D235/06—Benzimidazoles; Hydrogenated benzimidazoles with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 2
    • C07D235/08—Radicals containing only hydrogen and carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F7/00—Compounds containing elements of Groups 4 or 14 of the Periodic System
    • C07F7/02—Silicon compounds
    • C07F7/08—Compounds having one or more C—Si linkages
    • C07F7/18—Compounds having one or more C—Si linkages as well as one or more C—O—Si linkages
    • C07F7/1804—Compounds having Si-O-C linkages
HU9300390A 1990-08-15 1991-08-15 Process for the production of imidazole-condensed-compounds and pharmaceutical compositions containing them HUT65983A (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB909017878A GB9017878D0 (en) 1990-08-15 1990-08-15 Compounds
GB909018040A GB9018040D0 (en) 1990-08-16 1990-08-16 Compounds
GB919112857A GB9112857D0 (en) 1991-06-14 1991-06-14 Compounds

Publications (2)

Publication Number Publication Date
HU9300390D0 HU9300390D0 (en) 1993-04-28
HUT65983A true HUT65983A (en) 1994-08-29

Family

ID=27265234

Family Applications (2)

Application Number Title Priority Date Filing Date
HU9300390A HUT65983A (en) 1990-08-15 1991-08-15 Process for the production of imidazole-condensed-compounds and pharmaceutical compositions containing them
HU94P/P00003P HU210218A9 (en) 1990-08-15 1994-07-01 Heterobicyclic containing benzene sulfonamides which are platelet activating factor antagonists

Family Applications After (1)

Application Number Title Priority Date Filing Date
HU94P/P00003P HU210218A9 (en) 1990-08-15 1994-07-01 Heterobicyclic containing benzene sulfonamides which are platelet activating factor antagonists

Country Status (17)

Country Link
US (2) US5200412A (hu)
EP (1) EP0543861B1 (hu)
JP (1) JP3218243B2 (hu)
KR (1) KR930701412A (hu)
AT (1) ATE172195T1 (hu)
AU (1) AU657920B2 (hu)
CA (1) CA2088742C (hu)
DE (1) DE69130362T2 (hu)
ES (1) ES2123511T3 (hu)
FI (1) FI930633A (hu)
HU (2) HUT65983A (hu)
IE (1) IE912874A1 (hu)
NO (2) NO301229B1 (hu)
NZ (1) NZ239408A (hu)
PT (1) PT98674B (hu)
TW (1) TW199860B (hu)
WO (1) WO1992003422A1 (hu)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IE70217B1 (en) * 1990-08-15 1996-10-30 British Bio Technology Benzimidazole derivatives process for their preparation and application
US5466704A (en) * 1991-02-26 1995-11-14 E. R. Squibb & Sons, Inc. N-substituted imidazole and benzimidazole derivatives useful as angiotenson II antagonists
GB9122308D0 (en) * 1991-10-21 1991-12-04 British Bio Technology Compounds
GB9200209D0 (en) * 1992-01-07 1992-02-26 British Bio Technology Compounds
GB9200245D0 (en) * 1992-01-07 1992-02-26 British Bio Technology Compounds
GB9201755D0 (en) * 1992-01-28 1992-03-11 British Bio Technology Compounds
GB9202791D0 (en) * 1992-02-11 1992-03-25 British Bio Technology Compounds
IL111785A0 (en) 1993-12-03 1995-01-24 Ferring Bv Dp-iv inhibitors and pharmaceutical compositions containing them
CA2196792A1 (en) 1994-08-04 1996-02-15 Yoon T. Jeon Novel benzimidazole derivatives
GB9508748D0 (en) * 1995-04-28 1995-06-14 British Biotech Pharm Benzimidazole derivatives
US6495583B1 (en) 1997-03-25 2002-12-17 Synaptic Pharmaceutical Corporation Benzimidazole derivatives
FR2776925B3 (fr) * 1998-04-07 2000-05-26 Sanofi Sa Utilisation de derives d'aminothiazole pour la preparation de medicaments pour le traitement des maladies entrainant une demyelinisation
DE60316416T2 (de) * 2002-03-25 2008-06-26 Merck & Co., Inc. Heterocyclische beta-aminoverbindungen als inhibitoren der dipeptidylpeptidase zur behandlung bzw. prävention von diabetes
GB201321735D0 (en) 2013-12-09 2014-01-22 Ucb Pharma Sa Therapeutic Agents
CN113292873B (zh) * 2021-05-11 2022-03-08 重庆工程职业技术学院 一种煤矿矿井巷道喷涂材料及其制备方法
WO2023143520A1 (en) * 2022-01-28 2023-08-03 Insilico Medicine Ip Limited Ectonucleotide pyrophosphatase-phosphodiesterase 1 (enpp1) inhibitors and uses thereof

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL6715600A (hu) * 1966-12-02 1968-06-04
US4612323A (en) * 1983-06-27 1986-09-16 Sumitomo Chemical Company, Limited Insecticidal and acaricidal derivatives of 1-benzylbenzimidazole
US4539332A (en) * 1983-11-14 1985-09-03 Merck & Co., Inc. 2,5-Diaryl tetrahydrofurans and analogs thereof as PAF-antagonists
JP2556849B2 (ja) * 1986-02-13 1996-11-27 三共株式会社 グリセリン誘導体
US4804658A (en) * 1986-09-15 1989-02-14 G. D. Searle & Co. Imidazopyridine derivatives and pharmaceutical compositions
US4914108A (en) * 1988-03-14 1990-04-03 G. D. Searle & Co. 5-substituted(4,5-c)imidazopyridine compounds which have useful platelet activating factor antagonistic activity
AU616508B2 (en) * 1988-03-15 1991-10-31 G.D. Searle & Co. Benzyl-imidazo (4,5-c) pyridines
GB8904174D0 (en) * 1989-02-23 1989-04-05 British Bio Technology Compounds
IL94390A (en) * 1989-05-30 1996-03-31 Merck & Co Inc The 6-membered trans-nitrogen-containing heterocycles are compressed with imidazo and pharmaceutical preparations containing them
US5157026A (en) * 1989-05-30 1992-10-20 Merck & Co., Inc. Oxo-purines as angiotensin II antagonists
IE70217B1 (en) * 1990-08-15 1996-10-30 British Bio Technology Benzimidazole derivatives process for their preparation and application

Also Published As

Publication number Publication date
PT98674B (pt) 1999-01-29
KR930701412A (ko) 1993-06-11
NO301229B1 (no) 1997-09-29
FI930633A (fi) 1993-04-07
ATE172195T1 (de) 1998-10-15
AU657920B2 (en) 1995-03-30
NO973981D0 (no) 1997-08-29
US5200412A (en) 1993-04-06
NO930499L (no) 1993-04-14
EP0543861B1 (en) 1998-10-14
DE69130362T2 (de) 1999-04-01
NO930499D0 (no) 1993-02-12
PT98674A (pt) 1992-07-31
AU8421691A (en) 1992-03-17
EP0543861A1 (en) 1993-06-02
HU9300390D0 (en) 1993-04-28
WO1992003422A1 (en) 1992-03-05
US5276153A (en) 1994-01-04
IE912874A1 (en) 1992-02-26
DE69130362D1 (de) 1998-11-19
NZ239408A (en) 1993-12-23
ES2123511T3 (es) 1999-01-16
FI930633A0 (fi) 1993-02-12
CA2088742C (en) 2002-02-12
JPH06500085A (ja) 1994-01-06
CA2088742A1 (en) 1992-02-16
NO973981L (no) 1993-04-14
TW199860B (hu) 1993-02-11
HU210218A9 (en) 1995-02-28
JP3218243B2 (ja) 2001-10-15

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Legal Events

Date Code Title Description
DFC4 Cancellation of temporary protection due to refusal