HUT59696A - Process for producing platelet-activating polypeptide inhibitors and methods, combinations and compositions utilizing them - Google Patents

Process for producing platelet-activating polypeptide inhibitors and methods, combinations and compositions utilizing them

Info

Publication number
HUT59696A
HUT59696A HU901649A HU164990A HUT59696A HU T59696 A HUT59696 A HU T59696A HU 901649 A HU901649 A HU 901649A HU 164990 A HU164990 A HU 164990A HU T59696 A HUT59696 A HU T59696A
Authority
HU
Hungary
Prior art keywords
combinations
methods
activating polypeptide
compositions utilizing
polypeptide inhibitors
Prior art date
Application number
HU901649A
Other languages
English (en)
Inventor
John M Maraganore
Joseph A Jakubowski
Betty H Chao
Original Assignee
Biogen Inc
Univ Boston
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Biogen Inc, Univ Boston filed Critical Biogen Inc
Publication of HUT59696A publication Critical patent/HUT59696A/hu

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/78—Connective tissue peptides, e.g. collagen, elastin, laminin, fibronectin, vitronectin or cold insoluble globulin [CIG]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S530/00—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
    • Y10S530/855—Proteins from animals other than mammals or birds
    • Y10S530/856—Snakes; venom

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Molecular Biology (AREA)
  • Zoology (AREA)
  • Toxicology (AREA)
  • Hematology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Diabetes (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
HU901649A 1989-01-27 1990-01-26 Process for producing platelet-activating polypeptide inhibitors and methods, combinations and compositions utilizing them HUT59696A (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US30359089A 1989-01-27 1989-01-27
US30358589A 1989-01-27 1989-01-27
US07/430,313 US5182260A (en) 1989-01-27 1989-11-01 Dna sequences encoding snake venom inhibitors of platelet activation processes for producing those inhibitors and compositions using them

Publications (1)

Publication Number Publication Date
HUT59696A true HUT59696A (en) 1992-06-29

Family

ID=27404950

Family Applications (1)

Application Number Title Priority Date Filing Date
HU901649A HUT59696A (en) 1989-01-27 1990-01-26 Process for producing platelet-activating polypeptide inhibitors and methods, combinations and compositions utilizing them

Country Status (7)

Country Link
US (1) US5182260A (hu)
EP (1) EP0455722A1 (hu)
JP (1) JPH04505753A (hu)
CA (1) CA2045692A1 (hu)
FI (1) FI913592A0 (hu)
HU (1) HUT59696A (hu)
WO (1) WO1990008772A1 (hu)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5795867A (en) * 1989-06-16 1998-08-18 Cor Therapeutics, Inc. Platelet aggregation inhibitors
US5318899A (en) * 1989-06-16 1994-06-07 Cor Therapeutics, Inc. Platelet aggregation inhibitors
US5770564A (en) * 1989-06-16 1998-06-23 Cor Therapeutics, Inc. Platelet aggregation inhibitors
US5242810A (en) * 1990-12-07 1993-09-07 Biogen, Inc. Bifunctional inhibitors of thrombin and platelet activation
DE4203965A1 (de) * 1992-02-11 1993-08-12 Max Planck Gesellschaft Antidot fuer hirudin und synthetische thrombininhibitoren
KR100330465B1 (ko) * 1993-06-11 2002-11-23 메렐 파마슈티칼스 인크. 삼관능성항트롬빈및항혈소판펩티드
US7220724B2 (en) 1993-10-22 2007-05-22 University Of Southern California Contortrostatin CN and methods for its use in preventing metastasis and other conditions
US5731288A (en) * 1993-10-22 1998-03-24 University Of Southern California Compositions containing contortrostatin and methods for the use thereof
KR0142606B1 (ko) * 1995-07-05 1998-07-01 허영섭 혈소판 응집 억제 펩타이드 및 그의 제조방법
CA2253402A1 (en) * 1996-05-15 1997-11-20 G.D. Searle & Co. Method and reagent for monitoring blood levels of antiplatelet compounds
US5985833A (en) * 1996-09-17 1999-11-16 Wisconsin Alumni Research Foundation Thrombin inhibitor
CA2343716C (en) * 1998-09-29 2013-01-22 The University Of Southern California Contortrostatin (cn) and methods for its use in preventing metastasis and other conditions
WO2000056885A1 (en) * 1999-03-18 2000-09-28 Merck Patent Gmbh Protein for blocking platelet adhesion
EP1235586A4 (en) * 1999-12-10 2005-08-03 Univ Southern California CONTORTROSTATIN (CN) AND METHODS OF USE THEREOF FOR PREVENTING METASTASES AND OTHER PATHOGENESIS
JP2007502112A (ja) * 2003-08-12 2007-02-08 ユニバーシティ オブ ユタ リサーチ ファウンデーション ヘパリン結合タンパク質：ヘパリン検出のためのセンサー
US20110034396A1 (en) * 2005-09-28 2011-02-10 Biovascular, Inc. Methods and compositions for inhibiting cell migration and treatment of inflammatory conditions
WO2007038749A2 (en) * 2005-09-28 2007-04-05 Biovascular, Inc. Methods and compositions for blocking platelet and cell adhesion, cell migration and inflammation
US7259237B1 (en) * 2006-12-29 2007-08-21 Miller Kent D Pan-antiviral peptides
US9220743B2 (en) * 2010-01-22 2015-12-29 Nuovo Biologics, Llc Pan-antiviral peptides for protein kinase inhibition

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3743722A (en) * 1971-07-14 1973-07-03 Abbott Lab Anti-coagulant isolation
US3879369A (en) * 1972-05-12 1975-04-22 Abbott Lab Anti-coagulant isolation from malayan pit viper using affinity chromatography
US4341762A (en) * 1981-04-07 1982-07-27 Haast William E Use of snake venoms for treatment of neurological and related disorders
US4578079A (en) * 1982-08-04 1986-03-25 La Jolla Cancer Research Foundation Tetrapeptide
US4683291A (en) * 1985-10-28 1987-07-28 Scripps Clinic And Research Foundation Platelet binding inhibitors
US4741902A (en) * 1986-07-14 1988-05-03 Haast William E Compositions for treatment of neurological and related disorders
DE3886175T2 (de) * 1987-11-18 1994-04-07 Univ Temple Trigramin, ein Polypeptid, das die Aggregation der Blutplättchen hemmt.
NZ228710A (en) * 1988-04-22 1992-10-28 Merck & Co Inc Modified "echistatin" and anti-clotting pharmaceutical composition

Also Published As

Publication number Publication date
FI913592A0 (fi) 1991-07-26
US5182260A (en) 1993-01-26
WO1990008772A1 (en) 1990-08-09
JPH04505753A (ja) 1992-10-08
CA2045692A1 (en) 1990-07-28
EP0455722A1 (en) 1991-11-13

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Legal Events

Date Code Title Description
DFD9 Temporary prot. cancelled due to non-payment of fee