HUT59135A - Process for producing new thiazole derivatves and pharmaceutical compositions comprising such compounds - Google Patents

Process for producing new thiazole derivatves and pharmaceutical compositions comprising such compounds

Info

Publication number
HUT59135A
HUT59135A HU905918A HU591890A HUT59135A HU T59135 A HUT59135 A HU T59135A HU 905918 A HU905918 A HU 905918A HU 591890 A HU591890 A HU 591890A HU T59135 A HUT59135 A HU T59135A
Authority
HU
Hungary
Prior art keywords
derivatves
compounds
pharmaceutical compositions
producing new
new thiazole
Prior art date
Application number
HU905918A
Other languages
English (en)
Other versions
HU905918D0 (en
Inventor
Hisashi Takasugi
Yousuke Katsura
Tetsuo Tomishi
Yoshikazu Inoue
Original Assignee
Fujisawa Pharmaceutical Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB898920977A external-priority patent/GB8920977D0/en
Priority claimed from GB898928610A external-priority patent/GB8928610D0/en
Priority claimed from GB909012962A external-priority patent/GB9012962D0/en
Application filed by Fujisawa Pharmaceutical Co filed Critical Fujisawa Pharmaceutical Co
Publication of HU905918D0 publication Critical patent/HU905918D0/hu
Publication of HUT59135A publication Critical patent/HUT59135A/hu

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D277/00Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/20Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D277/22Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C07D277/28Radicals substituted by nitrogen atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D417/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/04Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D277/00Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/20Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D277/32Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D277/38Nitrogen atoms
    • C07D277/44Acylated amino or imino radicals
    • C07D277/48Acylated amino or imino radicals by radicals derived from carbonic acid, or sulfur or nitrogen analogues thereof, e.g. carbonylguanidines
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D417/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/14Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
HU905918A 1989-09-15 1990-09-14 Process for producing new thiazole derivatves and pharmaceutical compositions comprising such compounds HUT59135A (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB898920977A GB8920977D0 (en) 1989-09-15 1989-09-15 New pyridylthiazole derivatives,processes for the preparation thereof and pharmaceutical composition comprising the same
GB898928610A GB8928610D0 (en) 1989-12-19 1989-12-19 New thiazolthiazole derivatives,processes for the preparation thereof and pharmaceutical composition comprising the same
GB909012962A GB9012962D0 (en) 1990-06-11 1990-06-11 New thiazole derivatives,processes for the preparation thereof and pharmaceutical composition comprising the same

Publications (2)

Publication Number Publication Date
HU905918D0 HU905918D0 (en) 1991-03-28
HUT59135A true HUT59135A (en) 1992-04-28

Family

ID=27264690

Family Applications (1)

Application Number Title Priority Date Filing Date
HU905918A HUT59135A (en) 1989-09-15 1990-09-14 Process for producing new thiazole derivatves and pharmaceutical compositions comprising such compounds

Country Status (12)

Country Link
US (1) US5371097A (hu)
EP (1) EP0417751A3 (hu)
JP (1) JPH0730056B2 (hu)
KR (1) KR910006256A (hu)
AU (1) AU641425B2 (hu)
CA (1) CA2025356A1 (hu)
FI (1) FI904533A0 (hu)
HU (1) HUT59135A (hu)
IE (1) IE903216A1 (hu)
IL (1) IL95548A0 (hu)
NO (1) NO904020L (hu)
PT (1) PT95317A (hu)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE4134467A1 (de) 1991-10-18 1993-04-22 Thomae Gmbh Dr K Heterobiarylderivate, diese verbindungen enthaltende arzneimittel und verfahren zu ihrer herstellung
EP0575614A1 (en) * 1991-03-13 1993-12-29 Fujisawa Pharmaceutical Co., Ltd. Thiazole derivatives
GB9211163D0 (en) * 1992-05-26 1992-07-08 Fujisawa Pharmaceutical Co New oxazole derivatives
US5380734A (en) * 1993-04-15 1995-01-10 American Home Products Corporation N-cyanoamidine derivatives as anti-influenza agents
WO1994027606A1 (en) * 1993-05-28 1994-12-08 Unisearch Limited Method of treating helicobacter pylori infection
AU1504599A (en) * 1997-12-17 1999-07-05 Shionogi & Co., Ltd. Novel pyridine compounds
SI0928793T1 (en) * 1998-01-02 2002-10-31 F. Hoffmann-La Roche Ag Thiazole derivatives
US6001855A (en) * 1998-01-02 1999-12-14 Hoffman-La Roche Inc. Thiazole derivatives
KR100469219B1 (ko) 1998-10-22 2005-02-07 에프. 호프만-라 로슈 아게 티아졸-유도체
DE102004008141A1 (de) 2004-02-19 2005-09-01 Abbott Gmbh & Co. Kg Guanidinverbindungen und ihre Verwendung als Bindungspartner für 5-HT5-Rezeptoren
WO2006034003A2 (en) * 2004-09-17 2006-03-30 Whitehead Institute For Biomedical Research Compounds, compositions and methods of inhibiting a-synuclein toxicity
EP1939181A1 (en) 2006-12-27 2008-07-02 sanofi-aventis Heteroaryl-substituted carboxamides and use thereof for the stimulation of the expression of NO synthase
AR065785A1 (es) * 2007-03-19 2009-07-01 Xenon Pharmaceuticals Inc Compuestos biarilo y biheteroarilo de utilidad en el tratamiento de trastornos de hierro
US20230349922A1 (en) 2020-08-11 2023-11-02 Université De Strasbourg H2 Blockers Targeting Liver Macrophages for the Prevention and Treatment of Liver Disease and Cancer

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2961923D1 (en) * 1978-01-18 1982-03-11 Ici Plc Antisecretory guanidine derivatives, processes for their manufacture and pharmaceutical compositions containing them
DE2805756A1 (de) * 1978-02-10 1979-08-16 Bayer Ag N-azolylalkyl-aniline sowie verfahren zu ihrer herstellung
US4374843A (en) * 1980-10-14 1983-02-22 Pfizer Inc. 2-Guanidino-4-heteroarylthiazoles
IN163170B (hu) * 1980-10-14 1988-08-20 Pfizer
JPS5936674A (ja) * 1982-08-25 1984-02-28 Yamanouchi Pharmaceut Co Ltd N−置換グアニジノチアゾ−ル誘導体およびその製造法
US4649146A (en) * 1983-01-31 1987-03-10 Fujisawa Pharmaceutical Co., Ltd. Thiazole derivatives and pharmaceutical composition comprising the same
JPS59225186A (ja) * 1983-05-18 1984-12-18 Yamanouchi Pharmaceut Co Ltd 新規なグアニジノチアゾ−ル誘導体及びその製造方法
JPH0723982B2 (ja) * 1984-04-20 1995-03-15 コニカ株式会社 クリ−ニング装置
US4560690A (en) * 1984-04-30 1985-12-24 Pfizer Inc. 2-(N-substituted guanidino)-4-hetero-arylthiazole antiulcer agents
JPS62273977A (ja) * 1986-05-21 1987-11-28 Yoshitomi Pharmaceut Ind Ltd フリルチアゾ−ル化合物
FR2609603B1 (fr) * 1987-01-15 1989-03-24 Univ Claude Bernard Lyon Agents edulcorants derives des acides guanidinoacetique et ethanamidinoacetique, procede pour edulcorer des produits divers, et compositions contenant de tels agents edulcorants
IL91152A0 (en) * 1988-08-15 1990-03-19 Fujisawa Pharmaceutical Co Furylthiazole derivatives,processes for the preparation thereof and pharmaceutical compositions containing the same
EP0372125A1 (en) * 1988-11-08 1990-06-13 Akzo N.V. Oxazole and thiazole derivatives

Also Published As

Publication number Publication date
EP0417751A2 (en) 1991-03-20
EP0417751A3 (en) 1991-09-11
JPH0730056B2 (ja) 1995-04-05
JPH03141270A (ja) 1991-06-17
KR910006256A (ko) 1991-04-29
NO904020L (no) 1991-03-18
AU6242190A (en) 1991-03-21
PT95317A (pt) 1991-05-22
NO904020D0 (no) 1990-09-14
FI904533A0 (fi) 1990-09-14
US5371097A (en) 1994-12-06
HU905918D0 (en) 1991-03-28
AU641425B2 (en) 1993-09-23
IL95548A0 (en) 1991-06-30
CA2025356A1 (en) 1991-03-16
IE903216A1 (en) 1991-03-27

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Legal Events

Date Code Title Description
DFD9 Temporary protection cancelled due to non-payment of fee