HUT57195A - New process for producing an isoxazole derivative - Google Patents

New process for producing an isoxazole derivative

Info

Publication number
HUT57195A
HUT57195A HU633489A HU633489A HUT57195A HU T57195 A HUT57195 A HU T57195A HU 633489 A HU633489 A HU 633489A HU 633489 A HU633489 A HU 633489A HU T57195 A HUT57195 A HU T57195A
Authority
HU
Hungary
Prior art keywords
ester
methyl
acid
producing
iso
Prior art date
Application number
HU633489A
Other languages
Hungarian (hu)
Other versions
HU896334D0 (en
HU205749B (en
Inventor
Istvanne Krasznai
Geza Tokar
Csaba Kiss
Ferenc Jurak
Attila Mandi
Miklos Nemes
Istvan Derczbach
Peter Pentek
Karolyne Hadobas
Tibor Hegedues
Original Assignee
Egyt Gyogyszervegyeszeti Gyar
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Egyt Gyogyszervegyeszeti Gyar filed Critical Egyt Gyogyszervegyeszeti Gyar
Priority to HU633489A priority Critical patent/HU205749B/en
Publication of HU896334D0 publication Critical patent/HU896334D0/en
Publication of HUT57195A publication Critical patent/HUT57195A/en
Publication of HU205749B publication Critical patent/HU205749B/en

Links

Abstract

5-methyl-3-carbamoyl-iso-oxazole of formula (I) is prepd. as follows: Methyl-ester of acetyl-pyruvic-acid of formula (III) is obtd. by base catalysed condensn. of oxalic-acid-di:tert-butyl-ester or oxalic-acid-di:iso-butyl-ester and acetone. (III) reacts with hydroxyl-amine-sulphate or hydroxylamine-hydrochloride to yield 5-methyl-iso-oxazole-3-carboxylic-acid-methyl-ester of formula (IV), (IV) reacts with ammonia by known means without being isolated or purified.
HU633489A 1989-12-01 1989-12-01 New process for producing an isoxazole derivative HU205749B (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
HU633489A HU205749B (en) 1989-12-01 1989-12-01 New process for producing an isoxazole derivative

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
HU633489A HU205749B (en) 1989-12-01 1989-12-01 New process for producing an isoxazole derivative

Publications (3)

Publication Number Publication Date
HU896334D0 HU896334D0 (en) 1990-02-28
HUT57195A true HUT57195A (en) 1991-11-28
HU205749B HU205749B (en) 1992-06-29

Family

ID=10971490

Family Applications (1)

Application Number Title Priority Date Filing Date
HU633489A HU205749B (en) 1989-12-01 1989-12-01 New process for producing an isoxazole derivative

Country Status (1)

Country Link
HU (1) HU205749B (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1068316C (en) * 1996-10-31 2001-07-11 昆山制药总厂 Process for synthesizing 5-methyl-isoxazole-3-carboxamide

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1068316C (en) * 1996-10-31 2001-07-11 昆山制药总厂 Process for synthesizing 5-methyl-isoxazole-3-carboxamide

Also Published As

Publication number Publication date
HU896334D0 (en) 1990-02-28
HU205749B (en) 1992-06-29

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Legal Events

Date Code Title Description
HMM4 Cancellation of final prot. due to non-payment of fee