HUT48901A - Process for producing 5-substituted-3'-azido-2',3'-dideoxy-ribonukleozides - Google Patents
Process for producing 5-substituted-3'-azido-2',3'-dideoxy-ribonukleozidesInfo
- Publication number
- HUT48901A HUT48901A HU610187A HU610187A HUT48901A HU T48901 A HUT48901 A HU T48901A HU 610187 A HU610187 A HU 610187A HU 610187 A HU610187 A HU 610187A HU T48901 A HUT48901 A HU T48901A
- Authority
- HU
- Hungary
- Prior art keywords
- cpds
- azido
- ribonukleozides
- dideoxy
- substituted
- Prior art date
Links
Landscapes
- Saccharide Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
For the prepn. of 5-substd.-3'-azido-2'.3'-di:-dezoxy- ribo-nucleosides of formula (VI) where R is a hydrogen or a halogen, atom, a 1-3C straight or branched gp.; in this case a subst. alkyl and particularly gp.,-cpds. (I) are tritylated to obtain cpds. (II), which are mesylated to cpds. (III). Mesyl-oxy gps. of cpds. are cleaved off cpds. (III) to yield cpds. (IV). These are de-trithylated at room temp. with acetic acid to cpds. (V). Cpds. (V) and alkali-metal anodes form cpds. (VI). The end product is purified by continuous ethyl-acetate extraction.
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
HU610187A HU198949B (en) | 1987-12-30 | 1987-12-30 | Process for producing 5-substituted-3'azido-2',3'-dideoxyribonucleosides |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
HU610187A HU198949B (en) | 1987-12-30 | 1987-12-30 | Process for producing 5-substituted-3'azido-2',3'-dideoxyribonucleosides |
Publications (2)
Publication Number | Publication Date |
---|---|
HUT48901A true HUT48901A (en) | 1989-07-28 |
HU198949B HU198949B (en) | 1989-12-28 |
Family
ID=10971207
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
HU610187A HU198949B (en) | 1987-12-30 | 1987-12-30 | Process for producing 5-substituted-3'azido-2',3'-dideoxyribonucleosides |
Country Status (1)
Country | Link |
---|---|
HU (1) | HU198949B (en) |
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1994026756A1 (en) * | 1993-05-12 | 1994-11-24 | Rhone-Poulenc Chemicals Limited | Preparation of fluoro-compounds |
WO1994026762A1 (en) * | 1993-05-12 | 1994-11-24 | Rhone-Poulenc Chemicals Limited | Preparation of fluoro-nucleosides and intermediates for use therein |
-
1987
- 1987-12-30 HU HU610187A patent/HU198949B/en not_active IP Right Cessation
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1994026756A1 (en) * | 1993-05-12 | 1994-11-24 | Rhone-Poulenc Chemicals Limited | Preparation of fluoro-compounds |
WO1994026762A1 (en) * | 1993-05-12 | 1994-11-24 | Rhone-Poulenc Chemicals Limited | Preparation of fluoro-nucleosides and intermediates for use therein |
Also Published As
Publication number | Publication date |
---|---|
HU198949B (en) | 1989-12-28 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
HU90 | Patent valid on 900628 | ||
HMM4 | Cancellation of final prot. due to non-payment of fee |