HUT47132A - Process for producing new 2beta, 16beta-diamono-androstane derivatives and pharmaceutical compositions comprising such compounds - Google Patents

Process for producing new 2beta, 16beta-diamono-androstane derivatives and pharmaceutical compositions comprising such compounds

Info

Publication number
HUT47132A
HUT47132A HU882058A HU205888A HUT47132A HU T47132 A HUT47132 A HU T47132A HU 882058 A HU882058 A HU 882058A HU 205888 A HU205888 A HU 205888A HU T47132 A HUT47132 A HU T47132A
Authority
HU
Hungary
Prior art keywords
diamono
16beta
2beta
compounds
pharmaceutical compositions
Prior art date
Application number
HU882058A
Other languages
English (en)
Other versions
HU198084B (en
Inventor
Thomas Sleigh
David S Savage
Robert Taylor
Original Assignee
Akzo Nv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Akzo Nv filed Critical Akzo Nv
Publication of HUT47132A publication Critical patent/HUT47132A/hu
Publication of HU198084B publication Critical patent/HU198084B/hu

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J1/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 17 beta by a carbon atom, e.g. estrane, androstane
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J43/00—Normal steroids having a nitrogen-containing hetero ring spiro-condensed or not condensed with the cyclopenta(a)hydrophenanthrene skeleton
    • C07J43/003—Normal steroids having a nitrogen-containing hetero ring spiro-condensed or not condensed with the cyclopenta(a)hydrophenanthrene skeleton not condensed
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00—Drugs for disorders of the muscular or neuromuscular system
    • A61P21/02—Muscle relaxants, e.g. for tetanus or cramps
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J13/00—Normal steroids containing carbon, hydrogen, halogen or oxygen having a carbon-to-carbon double bond from or to position 17
    • C07J13/005—Normal steroids containing carbon, hydrogen, halogen or oxygen having a carbon-to-carbon double bond from or to position 17 with double bond in position 16 (17)
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J31/00—Normal steroids containing one or more sulfur atoms not belonging to a hetero ring
    • C07J31/006—Normal steroids containing one or more sulfur atoms not belonging to a hetero ring not covered by C07J31/003
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J41/00—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
    • C07J41/0005—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring the nitrogen atom being directly linked to the cyclopenta(a)hydro phenanthrene skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J71/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton is condensed with a heterocyclic ring
    • C07J71/0005—Oxygen-containing hetero ring
    • C07J71/001—Oxiranes

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Neurology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pain & Pain Management (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Steroid Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
HU882058A 1987-04-23 1988-04-22 Process for producing new 2beta, 16beta-diaminoandrostane derivatives and pharmaceutical compositions comprising such compounds HU198084B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB878709565A GB8709565D0 (en) 1987-04-23 1987-04-23 2beta,16beta-diaminoandrostanes

Publications (2)

Publication Number Publication Date
HUT47132A true HUT47132A (en) 1989-01-30
HU198084B HU198084B (en) 1989-07-28

Family

ID=10616197

Family Applications (1)

Application Number Title Priority Date Filing Date
HU882058A HU198084B (en) 1987-04-23 1988-04-22 Process for producing new 2beta, 16beta-diaminoandrostane derivatives and pharmaceutical compositions comprising such compounds

Country Status (12)

Country Link
US (1) US4891366A (hu)
EP (1) EP0288102A1 (hu)
JP (1) JPS63280096A (hu)
KR (1) KR880012635A (hu)
AU (1) AU601036B2 (hu)
DK (1) DK221288A (hu)
FI (1) FI881899A (hu)
GB (1) GB8709565D0 (hu)
HU (1) HU198084B (hu)
NZ (1) NZ224317A (hu)
PT (1) PT87298A (hu)
ZA (1) ZA882522B (hu)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8708886D0 (en) * 1987-04-14 1987-05-20 Akzo Nv 2beta-morpholino-androstane derivatives
JP2797444B2 (ja) * 1989-06-09 1998-09-17 石川島播磨重工業株式会社 管の多周溶接方法
IE914274A1 (en) * 1990-12-21 1992-07-01 Akzo Nv USE OF 2ß,16ß-DIAMINO-3Ó,17-DIHYDROXY ANDROSTANE DERIVATIVES
CZ300694A3 (en) * 1993-12-02 1996-05-15 Akzo Nobel Nv Substituted 2beta-morpholinandrostane derivatives, process of their preparation, their use for preparing pharmaceutical preparations and pharmaceutical compositions containing thereof
IT1277700B1 (it) * 1995-12-22 1997-11-11 Poli Ind Chimica Spa Processo di preparazione di 2-beta, 16-beta-diamino 3-alfa, 17-beta- diacilossi 5-alfaandrostani, bloccanti neuromuscolari a struttura
JP2008522983A (ja) 2005-09-13 2008-07-03 シコール インコーポレイティド ロクロニウムブロミドの合成方法

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1138605A (en) * 1965-02-19 1969-01-01 Organon Labor Ltd Improvements in or relating to new 2-ß,16-ß-diamino-androstanes
DE2962627D1 (en) * 1978-09-05 1982-06-09 Akzo Nv Acid addition salts of 16-beta-monoquaternary ammonium derivatives of 2-beta, 16-beta-bis-piperidino-androstanes and pharmaceutical preparations containing same
GB8708886D0 (en) * 1987-04-14 1987-05-20 Akzo Nv 2beta-morpholino-androstane derivatives

Also Published As

Publication number Publication date
FI881899A0 (fi) 1988-04-22
AU601036B2 (en) 1990-08-30
DK221288A (da) 1988-10-24
DK221288D0 (da) 1988-04-22
HU198084B (en) 1989-07-28
EP0288102A1 (en) 1988-10-26
PT87298A (pt) 1989-05-12
JPS63280096A (ja) 1988-11-17
US4891366A (en) 1990-01-02
FI881899A (fi) 1988-10-24
AU1478688A (en) 1988-10-27
GB8709565D0 (en) 1987-05-28
KR880012635A (ko) 1988-11-28
ZA882522B (en) 1988-09-28
NZ224317A (en) 1990-05-28

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Legal Events

Date Code Title Description
HU90 Patent valid on 900628
HMM4 Cancellation of final prot. due to non-payment of fee