HUT36797A - Process for producing monosodium salt of 7-d-mandelamido-3-/1-sulfomethyl-tetrazol-5-y1-thio-methyl/-3-cepheme-4-carboxylic acid - Google Patents

Process for producing monosodium salt of 7-d-mandelamido-3-/1-sulfomethyl-tetrazol-5-y1-thio-methyl/-3-cepheme-4-carboxylic acid

Info

Publication number
HUT36797A
HUT36797A HU85726A HU72685A HUT36797A HU T36797 A HUT36797 A HU T36797A HU 85726 A HU85726 A HU 85726A HU 72685 A HU72685 A HU 72685A HU T36797 A HUT36797 A HU T36797A
Authority
HU
Hungary
Prior art keywords
mandelamido
cepheme
sulfomethyl
tetrazol
thio
Prior art date
Application number
HU85726A
Other languages
English (en)
Other versions
HU192330B (en
Inventor
Theodore J Polansky
Original Assignee
Smithkline Beckman Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Smithkline Beckman Corp filed Critical Smithkline Beckman Corp
Publication of HUT36797A publication Critical patent/HUT36797A/hu
Publication of HU192330B publication Critical patent/HU192330B/hu

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/14—Compounds having a nitrogen atom directly attached in position 7
    • C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
    • C07D501/20—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
    • C07D501/24—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids with hydrocarbon radicals, substituted by hetero atoms or hetero rings, attached in position 3
    • C07D501/36—Methylene radicals, substituted by sulfur atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Cephalosporin Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
HU85726A 1984-02-29 1985-02-27 Process for producing monosodium salt of 7-d-mandelicacid-amido-3-/1-sulfomethyl-tetrazol-5-yl-thio-methyl/-3-cepheme-4-carboxylic acid HU192330B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/584,590 US4576937A (en) 1984-02-29 1984-02-29 7-D-Mandelamido-3(1-sulfomethyltetrazol-5-yl)thiomethyl-3-cephem-4-carboxylic acid monosodium salt

Publications (2)

Publication Number Publication Date
HUT36797A true HUT36797A (en) 1985-10-28
HU192330B HU192330B (en) 1987-05-28

Family

ID=24337979

Family Applications (1)

Application Number Title Priority Date Filing Date
HU85726A HU192330B (en) 1984-02-29 1985-02-27 Process for producing monosodium salt of 7-d-mandelicacid-amido-3-/1-sulfomethyl-tetrazol-5-yl-thio-methyl/-3-cepheme-4-carboxylic acid

Country Status (25)

Country Link
US (1) US4576937A (hu)
EP (1) EP0154484B1 (hu)
JP (1) JPH0699446B2 (hu)
KR (1) KR920004821B1 (hu)
AR (1) AR246974A1 (hu)
AT (1) ATE36715T1 (hu)
AU (1) AU577571B2 (hu)
CA (1) CA1239390A (hu)
DE (1) DE3564577D1 (hu)
DK (1) DK161083C (hu)
EG (1) EG17773A (hu)
ES (1) ES8701182A1 (hu)
FI (1) FI83083C (hu)
GR (1) GR850493B (hu)
HK (1) HK78791A (hu)
HU (1) HU192330B (hu)
IE (1) IE58234B1 (hu)
IL (1) IL74455A (hu)
NO (1) NO164599C (hu)
NZ (1) NZ211233A (hu)
PH (1) PH20809A (hu)
PT (1) PT80031B (hu)
SG (1) SG67291G (hu)
ZA (1) ZA851477B (hu)
ZW (1) ZW2785A1 (hu)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NZ263721A (en) * 1993-03-25 1996-12-20 Smithkline Beecham Corp Crystalline benzathine salt of cefonicid n,n'-dibenzylethylene diamine-7-[(hydroxyphenylacetyl)amino-8-oxo-3-[[[1-(sulfomethyl)-1h-tetrazol -5-yl]thio]methyl]-5-thia-1-azabicyclo-[4,2,0]oct-2-ene-2-carboxylate, preparation thereof
IT1265341B1 (it) * 1993-07-16 1996-11-22 Farmabios Srl Procedimento per la preparazione di cefalosporine
US5705496A (en) * 1994-03-24 1998-01-06 Smithkline Beecham Corporation Crystalline benzathine salt of cefonicid and its preparation
GB9908776D0 (en) * 1999-04-16 1999-06-09 Smithkline Beecham Plc Formulation

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1119799A (en) * 1964-09-01 1968-07-10 Eastman Kodak Co Substituted mercapto-tetrazoles and their use in photographic processing methods
CH527215A (de) * 1967-04-15 1972-08-31 Fujisawa Pharmaceutical Co Verfahren zur Herstellung von 3,7-disubstituierten Cephalosporinderivaten
US3819623A (en) * 1968-04-12 1974-06-25 Fujisawa Pharmaceutical Co 3,7-disubstituted cephalosporin compounds
NL173169C (nl) * 1969-10-27 1983-12-16 Fujisawa Pharmaceutical Co Werkwijze voor het bereiden van een farmaceutisch preparaat met antibacteriele werking en werkwijze voor het bereiden van het daarvoor benodigde cephalosporinederivaat.
GB1478055A (en) * 1973-07-27 1977-06-29 Erba Carlo Spa Cephalosporin compounds
JPS57873B2 (hu) * 1973-12-25 1982-01-08
DE2512284A1 (de) * 1974-03-28 1975-10-09 Fujisawa Pharmaceutical Co Cephalosporansaeurederivate, verfahren zu ihrer herstellung und sie enthaltende pharmazeutische mittel
GB1509074A (en) * 1974-04-05 1978-04-26 Yamanouchi Pharma Co Ltd Cephalosporin derivatives
US4048311A (en) * 1976-01-08 1977-09-13 Smithkline Corporation 7-Acyl-3-(sulfonic acid and sulfamoyl substituted tetrazolyl thiomethyl)cephalosporins
PT67732A (en) * 1977-03-07 1978-04-01 Lilly Co Eli Process for preparing cephalosporin compounds
EP0156771A3 (en) * 1984-03-29 1986-03-19 Biochemie Gesellschaft M.B.H. Cephalosporins

Also Published As

Publication number Publication date
DK84885D0 (da) 1985-02-25
DE3564577D1 (de) 1988-09-29
ES540680A0 (es) 1986-11-16
JPS60202890A (ja) 1985-10-14
PT80031A (en) 1985-03-01
EP0154484A3 (en) 1986-08-13
NZ211233A (en) 1988-06-30
NO850791L (no) 1985-08-30
GR850493B (hu) 1985-06-26
SG67291G (en) 1991-09-13
IE850491L (en) 1985-08-29
AR246974A1 (es) 1994-10-31
EG17773A (en) 1991-06-30
FI83083B (fi) 1991-02-15
JPH0699446B2 (ja) 1994-12-07
ATE36715T1 (de) 1988-09-15
FI850790L (fi) 1985-08-30
EP0154484B1 (en) 1988-08-24
DK161083B (da) 1991-05-27
AU3921385A (en) 1985-09-05
KR850006543A (ko) 1985-10-14
NO164599B (no) 1990-07-16
HU192330B (en) 1987-05-28
KR920004821B1 (ko) 1992-06-18
DK161083C (da) 1991-11-04
PH20809A (en) 1987-04-21
IL74455A0 (en) 1985-05-31
DK84885A (da) 1985-08-30
NO164599C (no) 1990-10-24
CA1239390A (en) 1988-07-19
US4576937A (en) 1986-03-18
EP0154484A2 (en) 1985-09-11
IE58234B1 (en) 1993-08-11
FI850790A0 (fi) 1985-02-27
FI83083C (fi) 1991-05-27
ES8701182A1 (es) 1986-11-16
PT80031B (pt) 1987-09-18
AU577571B2 (en) 1988-09-29
HK78791A (en) 1991-10-11
IL74455A (en) 1988-09-30
ZA851477B (en) 1985-10-30
ZW2785A1 (en) 1985-05-22

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Legal Events

Date Code Title Description
HU90 Patent valid on 900628