HUP9903904A2 - Use of an oligosaccharide as an immunomodulator in a dermato-cosmetic composition - Google Patents
Use of an oligosaccharide as an immunomodulator in a dermato-cosmetic compositionInfo
- Publication number
- HUP9903904A2 HUP9903904A2 HU9903904A HUP9903904A HUP9903904A2 HU P9903904 A2 HUP9903904 A2 HU P9903904A2 HU 9903904 A HU9903904 A HU 9903904A HU P9903904 A HUP9903904 A HU P9903904A HU P9903904 A2 HUP9903904 A2 HU P9903904A2
- Authority
- HU
- Hungary
- Prior art keywords
- oligosaccharide
- petro
- hex
- subject
- tube
- Prior art date
Links
- 229920001542 oligosaccharide Polymers 0.000 title abstract 3
- 150000002482 oligosaccharides Chemical class 0.000 title abstract 3
- 239000002537 cosmetic Substances 0.000 title 1
- 239000002955 immunomodulating agent Substances 0.000 title 1
- 229940121354 immunomodulator Drugs 0.000 title 1
- 230000002584 immunomodulator Effects 0.000 title 1
- 206010020751 Hypersensitivity Diseases 0.000 abstract 2
- 230000002209 hydrophobic effect Effects 0.000 abstract 2
- GUBGYTABKSRVRQ-XLOQQCSPSA-N Alpha-Lactose Chemical compound O[C@@H]1[C@@H](O)[C@@H](O)[C@@H](CO)O[C@H]1O[C@@H]1[C@@H](CO)O[C@H](O)[C@H](O)[C@H]1O GUBGYTABKSRVRQ-XLOQQCSPSA-N 0.000 abstract 1
- DHMQDGOQFOQNFH-UHFFFAOYSA-N Glycine Natural products NCC(O)=O DHMQDGOQFOQNFH-UHFFFAOYSA-N 0.000 abstract 1
- 239000004471 Glycine Substances 0.000 abstract 1
- GUBGYTABKSRVRQ-QKKXKWKRSA-N Lactose Natural products OC[C@H]1O[C@@H](O[C@H]2[C@H](O)[C@@H](O)C(O)O[C@@H]2CO)[C@H](O)[C@@H](O)[C@H]1O GUBGYTABKSRVRQ-QKKXKWKRSA-N 0.000 abstract 1
- 230000024932 T cell mediated immunity Effects 0.000 abstract 1
- 208000026935 allergic disease Diseases 0.000 abstract 1
- 230000007815 allergy Effects 0.000 abstract 1
- DLRVVLDZNNYCBX-ZZFZYMBESA-N beta-melibiose Chemical compound O[C@@H]1[C@@H](O)[C@@H](O)[C@@H](CO)O[C@@H]1OC[C@@H]1[C@@H](O)[C@H](O)[C@@H](O)[C@H](O)O1 DLRVVLDZNNYCBX-ZZFZYMBESA-N 0.000 abstract 1
- 229940079593 drug Drugs 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 229930182830 galactose Natural products 0.000 abstract 1
- 150000002402 hexoses Chemical class 0.000 abstract 1
- 230000003308 immunostimulating effect Effects 0.000 abstract 1
- 230000001939 inductive effect Effects 0.000 abstract 1
- 239000008101 lactose Substances 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 150000002972 pentoses Chemical class 0.000 abstract 1
- 239000003209 petroleum derivative Substances 0.000 abstract 1
- 239000000843 powder Substances 0.000 abstract 1
- 208000024891 symptom Diseases 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7016—Disaccharides, e.g. lactose, lactulose
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/702—Oligosaccharides, i.e. having three to five saccharide radicals attached to each other by glycosidic linkages
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/06—Antipsoriatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Engineering & Computer Science (AREA)
- Organic Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Molecular Biology (AREA)
- Epidemiology (AREA)
- Immunology (AREA)
- Dermatology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Cosmetics (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Abstract
A találmány tárgyát őligőszacharid alkalmazása képezi cellűlárisimműnválaszt befőlyásűló, imműndűlátőr hatású gyógyszer előállítására,amely őligőszacharid 2-6, glikőzidős kötéssel kapcsőlódó csőpőrtőttartalmaz és a nem redűkáló végcsőpőrtja galaktóz, vagy ezek hidrőfóbcsőpőrttal szűbsztitűált származéka, és amely az alábbi (A) általánősképlettel írható le: galaktóz -n (a vagy b) - (hex)p, (A) ahől aképletben n az 1., 2., 3., 4., 5. vagy 6. pőzíciót jelöli, hex a- vagyb-kötésű/ hexóz vagy pentóz, p 1 és 5 közötti szám. A találmányszerinti megőldásban előnyösen melibiózt, laktózt vagy ezek hidrőfóbcsőpőrt addíciójával előállítható származékait alkalmazzák A találmánytárgya képezik az őligőszacharidőt taralmazó bőrgyógyászati-kőzmetikaikészítmények, valamint kőzmetikai eljárásők, példáűl túlérzékeny bőrkőzmetikai kezelésére. A találmány szerinti megőldás alkalmas -különösen érzékeny vagy hiperreaktív bőrű egyének esetében - bőrimműnő-allergiás eredetű tüneteinek enyhítésére vagy megszüntetésére. ŕThe subject of the invention is the use of an oligosaccharide for the production of a cellular immune response-inducing drug with an immunostimulant effect, which is an oligosaccharide containing 2-6 end-tube caps linked by a glycine bond and the non-reducing end tube cap is galactose, or their derivative substituted with a hydrophobic cap, and which can be described by the general formula (A) below: galac pond - n (a or b) - (hex)p, (A) where n represents the 1st, 2nd, 3rd, 4th, 5th or 6th position, hex a- or b-bonded/ hexose or pentose, p is a number between 1 and 5. The solution according to the invention preferably uses melibiose, lactose, or their derivatives that can be produced by adding hydrophobic tube powder. The subject of the invention is the dermatological-petroleum products that represent prehistoric times, as well as the petro-methods, e.g. for the treatment of hypersensitive skin petro-metics. The solution according to the invention is suitable - especially in the case of individuals with sensitive or hyperreactive skin - to relieve or eliminate symptoms of dermatological allergy. ŕ
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR9609649A FR2751876B1 (en) | 1996-07-31 | 1996-07-31 | USE OF AN OLIGOSACCHARIDE AS AN IMMUNOMODULATOR, DERMATO-COSMETIC COMPOSITION AND METHOD OF COSMETIC TREATMENT |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| HUP9903904A2 true HUP9903904A2 (en) | 2000-04-28 |
| HUP9903904A3 HUP9903904A3 (en) | 2000-05-29 |
Family
ID=9494678
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| HU9903904A HUP9903904A3 (en) | 1996-07-31 | 1997-07-30 | Use of an oligosaccharide as an immunomodulator in a dermato-cosmetic composition |
Country Status (15)
| Country | Link |
|---|---|
| EP (1) | EP0954322A1 (en) |
| JP (1) | JP2000516591A (en) |
| KR (1) | KR20000029754A (en) |
| CN (1) | CN1228705A (en) |
| AU (1) | AU3457697A (en) |
| BR (1) | BR9710630A (en) |
| CA (1) | CA2262564A1 (en) |
| CZ (1) | CZ29599A3 (en) |
| FR (1) | FR2751876B1 (en) |
| HU (1) | HUP9903904A3 (en) |
| NZ (1) | NZ333985A (en) |
| PL (1) | PL331478A1 (en) |
| RU (1) | RU99104398A (en) |
| SK (1) | SK12199A3 (en) |
| WO (1) | WO1998004270A1 (en) |
Families Citing this family (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE19836339B4 (en) | 1998-08-11 | 2011-12-22 | N.V. Nutricia | carbohydrate mix |
| CN100528169C (en) * | 2002-05-31 | 2009-08-19 | 天野酶株式会社 | Antiinflammatory agent, agent for preventing/ameliorating allergic diseases and functional food |
| EP2223691A1 (en) * | 2003-10-24 | 2010-09-01 | N.V. Nutricia | Immunemodulating oligosaccharides |
| JP2005281298A (en) * | 2004-03-04 | 2005-10-13 | Fancl Corp | T cell immunomodulator comprising melibiose as active ingredient |
| EP1597978A1 (en) | 2004-05-17 | 2005-11-23 | Nutricia N.V. | Synergism of GOS and polyfructose |
| EA200802038A1 (en) * | 2006-04-10 | 2009-06-30 | Александр Владимирович ДИКОВСКИЙ | PHARMACEUTICAL COMPOSITION OF ENTEROSORBENT AND PREBIOTICS, MEDICAL FORMS AND METHOD OF PREVENTION AND TREATMENT OF DISEASES OF THE GASTROINTESTINAL TRACT |
| GB0915315D0 (en) | 2009-09-03 | 2009-10-07 | Univ Manchester | Use of non-digestible oligosaccharides |
| GB2500585A (en) | 2012-03-23 | 2013-10-02 | Univ Manchester | Use of oligosaccharides to reduce skin pigmentation |
| CN105764518A (en) * | 2013-10-25 | 2016-07-13 | 红艇有限公司 | Dietary regime for treatment of acne and other inflammatory skin conditions |
| US11328621B2 (en) | 2013-10-25 | 2022-05-10 | Red Pinnace Limited | Dietary regime for treatment of acne and other inflammatory skin conditions |
| KR101689875B1 (en) | 2014-08-28 | 2016-12-26 | (주)셀아이콘랩 | Cosmetic composition for treating atopic dermatitis containing mixtures of peptide and amino acid |
| KR101689877B1 (en) | 2014-08-28 | 2016-12-26 | (주)셀아이콘랩 | Cosmetic composition for treating atopic dermatitis |
| KR102046566B1 (en) | 2018-08-09 | 2019-11-19 | 박정혜 | cosmetic composition for improving pruritus of skin |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2545087B1 (en) * | 1983-04-29 | 1985-12-27 | Malte Oeuvres Hospit Fses Ordr | NOVEL CARBOHYDRATE DERIVATIVES OF 5-HYDROXYTRYPTOPHANE, OBTAINMENT AND APPLICATION AS MEDICAMENTS |
| GR860379B (en) * | 1985-02-22 | 1986-06-11 | Akzo Nv | Novel disaccharide and trisaccharide derivatives of the lipid a type |
| CA2118405A1 (en) * | 1992-05-26 | 1993-09-12 | Robert Maurice Ippolito | Immunosuppressive and tolerogenic modified lewisc and lacnac compounds |
-
1996
- 1996-07-31 FR FR9609649A patent/FR2751876B1/en not_active Expired - Fee Related
-
1997
- 1997-07-30 EP EP97930717A patent/EP0954322A1/en not_active Withdrawn
- 1997-07-30 WO PCT/IB1997/000951 patent/WO1998004270A1/en not_active Application Discontinuation
- 1997-07-30 CA CA002262564A patent/CA2262564A1/en not_active Abandoned
- 1997-07-30 RU RU99104398A patent/RU99104398A/en unknown
- 1997-07-30 CZ CZ99295A patent/CZ29599A3/en unknown
- 1997-07-30 AU AU34576/97A patent/AU3457697A/en not_active Abandoned
- 1997-07-30 JP JP10508650A patent/JP2000516591A/en active Pending
- 1997-07-30 CN CN97197506A patent/CN1228705A/en active Pending
- 1997-07-30 PL PL97331478A patent/PL331478A1/en unknown
- 1997-07-30 HU HU9903904A patent/HUP9903904A3/en unknown
- 1997-07-30 KR KR1019997000867A patent/KR20000029754A/en not_active Application Discontinuation
- 1997-07-30 SK SK121-99A patent/SK12199A3/en unknown
- 1997-07-30 BR BR9710630-5A patent/BR9710630A/en unknown
- 1997-07-30 NZ NZ333985A patent/NZ333985A/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| JP2000516591A (en) | 2000-12-12 |
| RU99104398A (en) | 2001-02-20 |
| SK12199A3 (en) | 2000-01-18 |
| CA2262564A1 (en) | 1998-02-05 |
| AU3457697A (en) | 1998-02-20 |
| CZ29599A3 (en) | 1999-06-16 |
| CN1228705A (en) | 1999-09-15 |
| KR20000029754A (en) | 2000-05-25 |
| HUP9903904A3 (en) | 2000-05-29 |
| EP0954322A1 (en) | 1999-11-10 |
| FR2751876A1 (en) | 1998-02-06 |
| PL331478A1 (en) | 1999-07-19 |
| BR9710630A (en) | 2000-01-11 |
| NZ333985A (en) | 2000-09-29 |
| FR2751876B1 (en) | 1998-12-31 |
| WO1998004270A1 (en) | 1998-02-05 |
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