HUP9903869A2 - Oral composition comprising a triazole antifungal compound - Google Patents

Oral composition comprising a triazole antifungal compound

Info

Publication number
HUP9903869A2
HUP9903869A2 HU9903869A HUP9903869A HUP9903869A2 HU P9903869 A2 HUP9903869 A2 HU P9903869A2 HU 9903869 A HU9903869 A HU 9903869A HU P9903869 A HUP9903869 A HU P9903869A HU P9903869 A2 HUP9903869 A2 HU P9903869A2
Authority
HU
Hungary
Prior art keywords
anticidal
granules
oral composition
agent
antifungal compound
Prior art date
Application number
HU9903869A
Other languages
Hungarian (hu)
Inventor
Ping I. Lee
Surendra A. Sangekar
Winston A. Vadino
Original Assignee
Schering Corp.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Schering Corp. filed Critical Schering Corp.
Publication of HUP9903869A2 publication Critical patent/HUP9903869A2/en
Publication of HUP9903869A3 publication Critical patent/HUP9903869A3/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/167—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction with an outer layer or coating comprising drug; with chemically bound drugs or non-active substances on their surface
    • A61K9/1676—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction with an outer layer or coating comprising drug; with chemically bound drugs or non-active substances on their surface having a drug-free core with discrete complete coating layer containing drug
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/496—Non-condensed piperazines containing further heterocyclic rings, e.g. rifampin, thiothixene
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/10—Antimycotics

Abstract

A találmány tárgyát növelt vagy javítőtt biőlógiai hasznősűlásúkészítmény triazől gőmbaölő szert tartalmazó gyógyászati keszítményekképezik, amelyek hatásős gőmbaölő aktivitással és/vagy biőlógiaihasznősűlással rendelkeznek. A találmány szerinti gyógyászatikészítményeket az alábbiakat tartalmazzák: i) szemcsék sőkaságát, amelyben az említett szemcsék ii) az (I) képletű gőmbaölő szerrel vannak bevőnva, és iii) egy kötőanyagőt, amely képes a gőmbaölő szert az említettszemcsékhez kötni. A találmány tárgyáhőz tartőznak a fenti készítményttartalmazó kapszűlák is. (I) ŕThe subject of the invention is an increased or improved biologically effective preparation containing a triazole anticidal agent, which has effective anticidal activity and/or biological efficacy. The pharmaceutical compositions according to the invention contain the following: i) a mass of granules, in which said granules are ii) coated with an anticidal agent of formula (I), and iii) a binding agent capable of binding the anticidal agent to said granules. The subject of the invention also includes the capsules containing the above preparation. (I) ŕ

HU9903869A 1996-06-28 1997-06-25 Oral composition comprising a triazole antifungal compound HUP9903869A3 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US67243296A 1996-06-28 1996-06-28
PCT/US1997/010122 WO1998000116A1 (en) 1996-06-28 1997-06-25 Oral composition comprising a triazole antifungal compound

Publications (2)

Publication Number Publication Date
HUP9903869A2 true HUP9903869A2 (en) 2000-06-28
HUP9903869A3 HUP9903869A3 (en) 2000-07-28

Family

ID=24698529

Family Applications (1)

Application Number Title Priority Date Filing Date
HU9903869A HUP9903869A3 (en) 1996-06-28 1997-06-25 Oral composition comprising a triazole antifungal compound

Country Status (16)

Country Link
EP (1) EP0914100A1 (en)
JP (1) JP2000514059A (en)
KR (1) KR20000022294A (en)
CN (1) CN1228693A (en)
AU (1) AU731704B2 (en)
BR (1) BR9710069A (en)
CA (1) CA2258683C (en)
CZ (1) CZ421498A3 (en)
HU (1) HUP9903869A3 (en)
IL (1) IL127780A0 (en)
NO (1) NO986087L (en)
NZ (1) NZ333514A (en)
PL (1) PL330864A1 (en)
SK (1) SK177598A3 (en)
TR (1) TR199802718T2 (en)
WO (1) WO1998000116A1 (en)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SI0969821T1 (en) * 1997-03-26 2003-10-31 Janssen Pharmaceutica N.V. Pellets having a core coated with an antifungal and a polymer
CA2301042A1 (en) * 1998-06-11 1999-12-16 Em Industries, Inc. Micro-osmotic controlled drug delivery systems
JP2002520351A (en) * 1998-07-17 2002-07-09 ジヤンセン・フアーマシユーチカ・ナームローゼ・フエンノートシヤツプ Pellets having a core coated with an antibacterial / mold agent and a polymer
ES2157731B1 (en) 1998-07-21 2002-05-01 Liconsa Liberacion Controlada ORAL PHARMACEUTICAL PREPARATION OF AN ANTIFUNGIC ACTIVITY COMPOUND AND PROCEDURE FOR PREPARATION.
US6248363B1 (en) * 1999-11-23 2001-06-19 Lipocine, Inc. Solid carriers for improved delivery of active ingredients in pharmaceutical compositions
US7863331B2 (en) 1999-07-09 2011-01-04 Ethypharm Pharmaceutical composition containing fenofibrate and method for the preparation thereof
FR2795961B1 (en) 1999-07-09 2004-05-28 Ethypharm Lab Prod Ethiques PHARMACEUTICAL COMPOSITION CONTAINING MICRONIZED FENOFIBRATE, A SURFACTANT AND A BINDING CELLULOSIC DERIVATIVE AND PREPARATION METHOD
KR100694667B1 (en) * 1999-12-08 2007-03-14 동아제약주식회사 Antifungal compositions containing itraconazole with both improved bioavailability and narrow intra- and inter-individual variation of its absorption
EP1842532A3 (en) * 2001-02-06 2009-04-22 Stiefel Laboratories, Inc. Oral sparingly water-soluble antifungal formulations and methods of making the same
US6663897B2 (en) * 2001-02-06 2003-12-16 Dsm Ip Assets B.V. Oral itraconazole formulations and methods of making the same
FR2842736B1 (en) 2002-07-26 2005-07-22 Flamel Tech Sa ORAL PHARMACEUTICAL FORMULATION IN THE FORM OF A PLURALITY OF MICROCAPSULES FOR PROLONGED RELEASE OF LOW SOLUBLE ACTIVE (S) PRINCIPLE (S)
ITMI20031096A1 (en) * 2003-05-30 2004-11-30 Eurand Spa MICROCAPS FOR COACERVATION CONTAINING DRUG INCORPORATED IN THE COATING POLYMER
DE10355461A1 (en) 2003-11-27 2005-06-23 Bayer Healthcare Ag Solid, high bioavailabilty oral formulations of N-substituted 5-chloro-2-thiophene-carboxamide derivative in hydrophilized form, useful for combating thrombo-embolic diseases
US11304960B2 (en) 2009-01-08 2022-04-19 Chandrashekar Giliyar Steroidal compositions
US9034858B2 (en) 2010-11-30 2015-05-19 Lipocine Inc. High-strength testosterone undecanoate compositions
US9358241B2 (en) 2010-11-30 2016-06-07 Lipocine Inc. High-strength testosterone undecanoate compositions
US20180153904A1 (en) 2010-11-30 2018-06-07 Lipocine Inc. High-strength testosterone undecanoate compositions
US20120148675A1 (en) 2010-12-10 2012-06-14 Basawaraj Chickmath Testosterone undecanoate compositions
US9498485B2 (en) 2014-08-28 2016-11-22 Lipocine Inc. Bioavailable solid state (17-β)-hydroxy-4-androsten-3-one esters
WO2016033549A2 (en) 2014-08-28 2016-03-03 Lipocine Inc. (17-ß)-3-OXOANDROST-4-EN-17-YL TRIDECANOATE COMPOSITIONS AND METHODS OF THEIR PREPARATION AND USE
CN105949278B (en) * 2016-03-30 2019-12-06 南京曼杰生物科技有限公司 Substituted tetrahydrofuran water-soluble derivative and application thereof
JP2020503269A (en) 2016-11-28 2020-01-30 リポカイン インコーポレーテッド Oral testosterone undecanoate therapy

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5580578A (en) * 1992-01-27 1996-12-03 Euro-Celtique, S.A. Controlled release formulations coated with aqueous dispersions of acrylic polymers
PH30929A (en) * 1992-09-03 1997-12-23 Janssen Pharmaceutica Nv Beads having a core coated with an antifungal and a polymer.
DK0736030T3 (en) * 1993-12-21 2001-10-29 Schering Corp Fungicidal tetrahydrofurans

Also Published As

Publication number Publication date
NO986087D0 (en) 1998-12-23
NZ333514A (en) 2000-05-26
KR20000022294A (en) 2000-04-25
IL127780A0 (en) 1999-10-28
WO1998000116A1 (en) 1998-01-08
JP2000514059A (en) 2000-10-24
CN1228693A (en) 1999-09-15
AU3387497A (en) 1998-01-21
CA2258683C (en) 2007-07-31
AU731704B2 (en) 2001-04-05
CA2258683A1 (en) 1998-01-08
CZ421498A3 (en) 1999-06-16
PL330864A1 (en) 1999-06-07
EP0914100A1 (en) 1999-05-12
NO986087L (en) 1999-02-26
SK177598A3 (en) 1999-07-12
HUP9903869A3 (en) 2000-07-28
TR199802718T2 (en) 1999-03-22
BR9710069A (en) 1999-08-10

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