HUP9903578A2 - Eljárás személyek, köztük májátültetésen átesett személyek mája állapotának meghatározására - Google Patents

Eljárás személyek, köztük májátültetésen átesett személyek mája állapotának meghatározására

Info

Publication number
HUP9903578A2
HUP9903578A2 HU9903578A HUP9903578A HUP9903578A2 HU P9903578 A2 HUP9903578 A2 HU P9903578A2 HU 9903578 A HU9903578 A HU 9903578A HU P9903578 A HUP9903578 A HU P9903578A HU P9903578 A2 HUP9903578 A2 HU P9903578A2
Authority
HU
Hungary
Prior art keywords
pgst
determining
individual
transplant recipient
liver transplant
Prior art date
Application number
HU9903578A
Other languages
English (en)
Inventor
John Martin Doyle
Cormac Gerard Kilty
Fiona Mary Manning
Original Assignee
Biotrin Intellectual Properties Limited
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Biotrin Intellectual Properties Limited filed Critical Biotrin Intellectual Properties Limited
Publication of HUP9903578A2 publication Critical patent/HUP9903578A2/hu

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/573—Immunoassay; Biospecific binding assay; Materials therefor for enzymes or isoenzymes
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/975—Kit

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Chemical & Material Sciences (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Cell Biology (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Microbiology (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Measuring And Recording Apparatus For Diagnosis (AREA)

Abstract

A találmány tárgyát képezi eljárás egy személy mája állapőtánakmeghatárőzására, amelyet az jellemez, hőgy a pGST-izőfőrmáraspecifikűs imműnőlógiai vizsgálati eljárással a személyből származóbiőlógiai főlyadékból vett mintában mérik a p-glűtatiőn S-transzferáz-izőfőrma (pGST) szintjét, a mért pGST-szintet összehasőnlítják abiőlógiai mintában nőrmális pGST-tartőmánnyal, majd amennyiben anőrmális tartőmányhőz képest a pGST-szint relatív növekedéséttapasztalják, a biőlógiai minta pGST-szintje alapján meghatárőzzák aszemély májának állapőtát. Az eljárás alkalmas májátültetés űtán igenkőrai fázisban a kilökődés esélyének megállapítására, mivel azelsődleges kilökődés általában az elágazó epevezetékekben következikbe. ŕ
HU9903578A 1996-02-02 1996-02-02 Eljárás személyek, köztük májátültetésen átesett személyek mája állapotának meghatározására HUP9903578A2 (hu)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CA002246072A CA2246072A1 (en) 1996-02-02 1996-02-02 Method of determining the hepatic status of an individual, including a liver transplant recipient
PCT/IE1996/000003 WO1997028449A1 (en) 1996-02-02 1996-02-02 Method of determining the hepatic status of an individual, including a liver transplant recipient

Publications (1)

Publication Number Publication Date
HUP9903578A2 true HUP9903578A2 (hu) 2000-02-28

Family

ID=25680448

Family Applications (1)

Application Number Title Priority Date Filing Date
HU9903578A HUP9903578A2 (hu) 1996-02-02 1996-02-02 Eljárás személyek, köztük májátültetésen átesett személyek mája állapotának meghatározására

Country Status (13)

Country Link
US (1) US6183977B1 (hu)
EP (1) EP0880700B1 (hu)
JP (1) JP2000505544A (hu)
AT (1) ATE322013T1 (hu)
AU (1) AU712180B2 (hu)
BR (1) BR9612475A (hu)
CA (1) CA2246072A1 (hu)
CZ (1) CZ287488B6 (hu)
DE (1) DE69635979T2 (hu)
ES (1) ES2262153T3 (hu)
HU (1) HUP9903578A2 (hu)
PL (1) PL328518A1 (hu)
WO (1) WO1997028449A1 (hu)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6977140B1 (en) 1998-09-29 2005-12-20 Organ Recovery Systems, Inc. Method for maintaining and/or restoring viability of organs
US6492103B1 (en) 2000-01-31 2002-12-10 Organ Recovery Systems, Inc. System for organ and tissue preservation and hypothermic blood substitution
CA2449175A1 (en) * 2001-06-05 2002-12-12 University Of Chicago Use of methylnaltrexone to treat immune suppression
US20040219600A1 (en) * 2002-12-13 2004-11-04 Williams Robert Wood Method for determining sensitivity to environmental toxins and susceptibility to parkinson's disease
US8048638B2 (en) 2005-04-01 2011-11-01 University Of Florida Research Foundation, Inc. Biomarkers of liver injury
JP5202296B2 (ja) * 2005-04-01 2013-06-05 ユニバーシティ オブ フロリダ リサーチ ファウンデーション，インコーポレイティド 肝臓傷害のバイオマーカー
US9682132B2 (en) 2010-01-26 2017-06-20 Banyan Biomarkers, Inc Compositions and methods relating to argininosucccinate synthetase

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU5435990A (en) 1989-04-13 1990-11-05 United States of America, as represented by the Secretary, U.S. Department of Commerce, The Monoclonal antibodies to human glutathione s transferase pi
JPH0425763A (ja) 1990-05-21 1992-01-29 Maruko Seiyaku Kk グルタチオンＳ―トランスフェラーゼπの定量方法および診断のための試薬
USRE35419E (en) * 1992-05-01 1997-01-07 Cormac G. Kilty Measurement of an enzyme marker as an aid to diagnosis of liver transplant rejection
US5217868A (en) * 1992-05-01 1993-06-08 Syncor Limited Measurement of an enzyme marker as an aid to diagnosis of liver transplant rejection

Also Published As

Publication number Publication date
ATE322013T1 (de) 2006-04-15
US6183977B1 (en) 2001-02-06
CZ287488B6 (en) 2000-12-13
BR9612475A (pt) 1999-07-13
DE69635979D1 (de) 2006-05-18
DE69635979T2 (de) 2006-11-16
AU712180B2 (en) 1999-10-28
ES2262153T3 (es) 2006-11-16
CZ228898A3 (cs) 1999-03-17
JP2000505544A (ja) 2000-05-09
CA2246072A1 (en) 1997-08-07
EP0880700B1 (en) 2006-03-29
PL328518A1 (en) 1999-02-01
WO1997028449A1 (en) 1997-08-07
EP0880700A1 (en) 1998-12-02
AU4632396A (en) 1997-08-22

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HUP9903578A2 (hu) Eljárás személyek, köztük májátültetésen átesett személyek mája állapotának meghatározására
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