AU2836299A - Use of 14-3-3 proteins as sensitive biological markers for detecting pollution caused, inter alia, by polychlorinated biphenyl (pcb) and (xeno)oestrogen and method for quick determination of 14-3-3 proteins - Google Patents
Use of 14-3-3 proteins as sensitive biological markers for detecting pollution caused, inter alia, by polychlorinated biphenyl (pcb) and (xeno)oestrogen and method for quick determination of 14-3-3 proteinsInfo
- Publication number
- AU2836299A AU2836299A AU28362/99A AU2836299A AU2836299A AU 2836299 A AU2836299 A AU 2836299A AU 28362/99 A AU28362/99 A AU 28362/99A AU 2836299 A AU2836299 A AU 2836299A AU 2836299 A AU2836299 A AU 2836299A
- Authority
- AU
- Australia
- Prior art keywords
- proteins
- xeno
- oestrogen
- pcb
- inter alia
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
- G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
- G01N33/5082—Supracellular entities, e.g. tissue, organisms
- G01N33/5085—Supracellular entities, e.g. tissue, organisms of invertebrates
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
- G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
- G01N33/5082—Supracellular entities, e.g. tissue, organisms
- G01N33/5088—Supracellular entities, e.g. tissue, organisms of vertebrates
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6893—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere
- G01N33/6896—Neurological disorders, e.g. Alzheimer's disease
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Immunology (AREA)
- Chemical & Material Sciences (AREA)
- Hematology (AREA)
- Urology & Nephrology (AREA)
- Molecular Biology (AREA)
- Cell Biology (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- Biotechnology (AREA)
- Pathology (AREA)
- General Physics & Mathematics (AREA)
- Food Science & Technology (AREA)
- Medicinal Chemistry (AREA)
- Physics & Mathematics (AREA)
- General Health & Medical Sciences (AREA)
- Microbiology (AREA)
- Toxicology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Tropical Medicine & Parasitology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Peptides Or Proteins (AREA)
- Steroid Compounds (AREA)
Abstract
Method for monitoring natural and anthropogenic environmental chemicals in water or soil comprises assaying for protein 14-3-3 (Trends Biochem. Sci., 17, 498, 1992) as a biomarker in vertebrate or invertebrate indicator organisms exposed to the water or soil. An independent claim is also included for an enzyme-linked immunosorbent assay (ELISA) for determining the presence and amount of protein 14-3-3 in an extract or body fluid sample, comprising: (1) introducing the sample into a microtiter plate well coated with a 14-3-3-binding peptide, either directly or by interaction of the biotinylated peptide with a streptavidin coating, and (2) detecting and quantifying complex formation. ACTIVITY : None given. MECHANISM OF ACTION : None given.
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE19810721A DE19810721A1 (en) | 1998-03-12 | 1998-03-12 | Application of the 14-3-3 proteins as well as methods for the rapid determination of the 14-3-3 proteins as sensitive biomarkers for pollution and. a. with polychlorinated biphenyls (PCBs) and (xeno) estrogens |
DE19810721 | 1998-03-12 | ||
PCT/EP1999/001545 WO1999046401A2 (en) | 1998-03-12 | 1999-03-10 | 14-3-3 proteins used as sensitive biological markers for detecting pollution caused, inter alia, by polychlorinated biphenyl (pcb) and (xeno)oestrogen |
Publications (1)
Publication Number | Publication Date |
---|---|
AU2836299A true AU2836299A (en) | 1999-09-27 |
Family
ID=7860626
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AU28362/99A Abandoned AU2836299A (en) | 1998-03-12 | 1999-03-10 | Use of 14-3-3 proteins as sensitive biological markers for detecting pollution caused, inter alia, by polychlorinated biphenyl (pcb) and (xeno)oestrogen and method for quick determination of 14-3-3 proteins |
Country Status (5)
Country | Link |
---|---|
EP (2) | EP1536235A3 (en) |
AT (1) | ATE295898T1 (en) |
AU (1) | AU2836299A (en) |
DE (3) | DE19810721A1 (en) |
WO (1) | WO1999046401A2 (en) |
Families Citing this family (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE10131912A1 (en) * | 2001-06-06 | 2002-12-19 | Werner E G Mueller | Determining isoforms of 14-3-3 family proteins, useful for early diagnosis of transmissible spongiform encephalopathies or toxicity testing |
ES2407975T3 (en) | 2006-05-09 | 2013-06-17 | The University Of British Columbia | Dissolved arthritis protein markers |
JP5781764B2 (en) * | 2007-11-27 | 2015-09-24 | ザ・ユニバーシティ・オブ・ブリティッシュ・コロンビア | 14-3-3η antibody and its use for the diagnosis and treatment of arthritis |
DK2768851T3 (en) | 2011-10-21 | 2017-09-18 | Augurex Life Sciences Corp | ANTIGENS DERIVED BY CITRULLINATED 14-3-3 AND APPLICATIONS THEREOF IN THE DIAGNOSIS OF RHEUMATOID ARTHRITIS |
KR101933692B1 (en) | 2017-07-12 | 2018-12-28 | 동국대학교 산학협력단 | Diagnostic kit comprising biomarkers for polychlorinated biphenyl 77 exposure diagnosis |
RU2702852C1 (en) * | 2018-07-20 | 2019-10-11 | федеральное государственное автономное образовательное учреждение высшего образования "Казанский (Приволжский) федеральный университет" (ФГАОУ ВО КФУ) | Method for using marker proteins of saprobic groups of indicator organisms for assessing ecological state of an environment |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5948765A (en) * | 1996-03-15 | 1999-09-07 | Washington University | Inhibition of intracellular signal transduction by 14-3-3-binding peptides |
US5998149A (en) * | 1996-04-05 | 1999-12-07 | The United States Of America As Represented By The Department Of Health And Human Services | Method of detecting transmissible spongiform encephalopathies |
-
1998
- 1998-03-12 DE DE19810721A patent/DE19810721A1/en not_active Withdrawn
-
1999
- 1999-03-10 WO PCT/EP1999/001545 patent/WO1999046401A2/en active IP Right Grant
- 1999-03-10 AT AT99908954T patent/ATE295898T1/en not_active IP Right Cessation
- 1999-03-10 AU AU28362/99A patent/AU2836299A/en not_active Abandoned
- 1999-03-10 EP EP04029992A patent/EP1536235A3/en not_active Withdrawn
- 1999-03-10 EP EP99908954A patent/EP0983377B1/en not_active Expired - Lifetime
- 1999-03-10 DE DE19980374T patent/DE19980374D2/en not_active Expired - Fee Related
- 1999-03-10 DE DE59912059T patent/DE59912059D1/en not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
DE19980374D2 (en) | 2000-09-28 |
WO1999046401A3 (en) | 2000-03-09 |
EP0983377B1 (en) | 2005-05-18 |
DE19810721A1 (en) | 1999-10-14 |
ATE295898T1 (en) | 2005-06-15 |
EP1536235A2 (en) | 2005-06-01 |
WO1999046401A2 (en) | 1999-09-16 |
DE59912059D1 (en) | 2005-06-23 |
EP0983377A1 (en) | 2000-03-08 |
EP1536235A3 (en) | 2005-09-07 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
MK6 | Application lapsed section 142(2)(f)/reg. 8.3(3) - pct applic. not entering national phase |