HUP9900942A2 - Medicament forms constituted in situ for releasing enzymes into wounds - Google Patents

Medicament forms constituted in situ for releasing enzymes into wounds

Info

Publication number
HUP9900942A2
HUP9900942A2 HU9900942A HUP9900942A HUP9900942A2 HU P9900942 A2 HUP9900942 A2 HU P9900942A2 HU 9900942 A HU9900942 A HU 9900942A HU P9900942 A HUP9900942 A HU P9900942A HU P9900942 A2 HUP9900942 A2 HU P9900942A2
Authority
HU
Hungary
Prior art keywords
wounds
situ
chamber
medicament forms
releasing enzymes
Prior art date
Application number
HU9900942A
Other languages
Hungarian (hu)
Inventor
Uwe Löffler
Thomas Moest
Original Assignee
Knoll Aktiengesellschaft
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Knoll Aktiengesellschaft filed Critical Knoll Aktiengesellschaft
Publication of HUP9900942A2 publication Critical patent/HUP9900942A2/en
Publication of HUP9900942A3 publication Critical patent/HUP9900942A3/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/06—Ointments; Bases therefor; Other semi-solid forms, e.g. creams, sticks, gels
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43—Enzymes; Proenzymes; Derivatives thereof
    • A61K38/46—Hydrolases (3)
    • A61K38/48—Hydrolases (3) acting on peptide bonds (3.4)
    • A61K38/4886—Metalloendopeptidases (3.4.24), e.g. collagenase
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like

Abstract

A találmány tárgya őlyan hatóanyagők külső felvitelére alkalmasrendszer, amelyek vízre érzékenyek, és kőcsőnyás állagúhőrdőzóanyaggal nehezen felvehetők; amely rendszer tartalmaz 1. egykamrát a hatóanyag - előnyösen sebtisztító enzimként kőllagenáz -részére, 2. egy kamrát egy őldószer részére, amelyben a hatóanyagkönnyen őldható, és 3. egy kamrát egy gélképző részére, emellett akamrák úgy vannak kialakítva, hőgy tartalműk győrsanösszekeveredhessen egymással. ŕThe subject of the invention is a system suitable for the external application of active ingredients that are sensitive to water and difficult to apply with a stone-like mortar; which system contains 1. a chamber for the active ingredient - preferably a wound-cleansing enzyme called llagenase, 2. a chamber for a solvent, in which the active ingredient can be easily dissolved, and 3. a chamber for a gel-forming part, in addition, the chambers are designed in such a way that heat content can be thoroughly mixed with each other. ŕ

HU9900942A 1996-01-23 1997-01-22 Medicament forms constituted in situ for releasing enzymes into wounds HUP9900942A3 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19602208A DE19602208A1 (en) 1996-01-23 1996-01-23 Pharmaceutical form formed in situ for the delivery of enzymes to wounds

Publications (2)

Publication Number Publication Date
HUP9900942A2 true HUP9900942A2 (en) 1999-08-30
HUP9900942A3 HUP9900942A3 (en) 2000-06-28

Family

ID=7783390

Family Applications (1)

Application Number Title Priority Date Filing Date
HU9900942A HUP9900942A3 (en) 1996-01-23 1997-01-22 Medicament forms constituted in situ for releasing enzymes into wounds

Country Status (14)

Country Link
EP (1) EP0876139A1 (en)
JP (1) JP2001518063A (en)
KR (1) KR19990081901A (en)
CN (1) CN1209739A (en)
AU (1) AU715587B2 (en)
BR (1) BR9707058A (en)
CA (1) CA2243528A1 (en)
CZ (1) CZ230198A3 (en)
DE (1) DE19602208A1 (en)
HU (1) HUP9900942A3 (en)
IL (1) IL125148A (en)
NO (1) NO983373L (en)
WO (1) WO1997026861A1 (en)
ZA (1) ZA97514B (en)

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2194144B (en) * 1986-08-22 1990-04-25 American Cyanamid Co Stable pharmaceutical gel preparation
US5580856A (en) * 1994-07-15 1996-12-03 Prestrelski; Steven J. Formulation of a reconstituted protein, and method and kit for the production thereof

Also Published As

Publication number Publication date
KR19990081901A (en) 1999-11-15
EP0876139A1 (en) 1998-11-11
HUP9900942A3 (en) 2000-06-28
CN1209739A (en) 1999-03-03
CZ230198A3 (en) 1999-02-17
JP2001518063A (en) 2001-10-09
AU1544297A (en) 1997-08-20
BR9707058A (en) 1999-07-20
DE19602208A1 (en) 1997-07-24
NO983373L (en) 1998-09-21
IL125148A0 (en) 1999-01-26
ZA97514B (en) 1998-07-22
AU715587B2 (en) 2000-02-03
NO983373D0 (en) 1998-07-22
CA2243528A1 (en) 1997-07-31
WO1997026861A1 (en) 1997-07-31
IL125148A (en) 2001-03-19

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