HUP9800776A2 - Method and apparatus for on-line treatment of blood in extracorporeal therapy, method and syringe pump for on-line delivering a predetermined concentration of a medicinal solution into a patient's blood and method for mixing first and second fluids mov... - Google Patents

Method and apparatus for on-line treatment of blood in extracorporeal therapy, method and syringe pump for on-line delivering a predetermined concentration of a medicinal solution into a patient's blood and method for mixing first and second fluids mov...

Info

Publication number
HUP9800776A2
HUP9800776A2 HU9800776A HUP9800776A HUP9800776A2 HU P9800776 A2 HUP9800776 A2 HU P9800776A2 HU 9800776 A HU9800776 A HU 9800776A HU P9800776 A HUP9800776 A HU P9800776A HU P9800776 A2 HUP9800776 A2 HU P9800776A2
Authority
HU
Hungary
Prior art keywords
blood
patient
releasable
delivery rate
block
Prior art date
Application number
HU9800776A
Other languages
Hungarian (hu)
Inventor
Dennis A. Briggs
Joseph Garro
Kyu H. Lee
Original Assignee
Therakos, Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Therakos, Inc. filed Critical Therakos, Inc.
Publication of HUP9800776A2 publication Critical patent/HUP9800776A2/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/14—Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis
    • A61M1/16—Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis with membranes
    • A61M1/1692—Detection of blood traces in dialysate
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F25/00—Flow mixers; Mixers for falling materials, e.g. solid particles
    • B01F25/40—Static mixers
    • B01F25/45—Mixers in which the materials to be mixed are pressed together through orifices or interstitial spaces, e.g. between beads
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/14—Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis
    • A61M1/30—Single needle dialysis ; Reciprocating systems, alternately withdrawing blood from and returning it to the patient, e.g. single-lumen-needle dialysis or single needle systems for hemofiltration or pheresis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/14—Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis
    • A61M1/30—Single needle dialysis ; Reciprocating systems, alternately withdrawing blood from and returning it to the patient, e.g. single-lumen-needle dialysis or single needle systems for hemofiltration or pheresis
    • A61M1/301—Details
    • A61M1/302—Details having a reservoir for withdrawn untreated blood
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/14—Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis
    • A61M1/30—Single needle dialysis ; Reciprocating systems, alternately withdrawing blood from and returning it to the patient, e.g. single-lumen-needle dialysis or single needle systems for hemofiltration or pheresis
    • A61M1/301—Details
    • A61M1/303—Details having a reservoir for treated blood to be returned
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/14—Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis
    • A61M1/30—Single needle dialysis ; Reciprocating systems, alternately withdrawing blood from and returning it to the patient, e.g. single-lumen-needle dialysis or single needle systems for hemofiltration or pheresis
    • A61M1/301—Details
    • A61M1/304—Treatment chamber used as reservoir, e.g. centrifuge bowl or filter with movable membrane
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/14—Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis
    • A61M1/30—Single needle dialysis ; Reciprocating systems, alternately withdrawing blood from and returning it to the patient, e.g. single-lumen-needle dialysis or single needle systems for hemofiltration or pheresis
    • A61M1/301—Details
    • A61M1/305—Control of inversion point between collection and re-infusion phase
    • A61M1/308—Volume control, e.g. with open or flexible containers, by counting the number of pump revolutions, weighing
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/36—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits
    • A61M1/3621—Extra-corporeal blood circuits
    • A61M1/3626—Gas bubble detectors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/36—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits
    • A61M1/3681—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits by irradiation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/36—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits
    • A61M1/3681—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits by irradiation
    • A61M1/3683—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits by irradiation using photoactive agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/36—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits
    • A61M1/3693—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits using separation based on different densities of components, e.g. centrifuging
    • A61M1/3696—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits using separation based on different densities of components, e.g. centrifuging with means for adding or withdrawing liquid substances during the centrifugation, e.g. continuous centrifugation
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F25/00—Flow mixers; Mixers for falling materials, e.g. solid particles
    • B01F25/40—Static mixers
    • B01F25/45—Mixers in which the materials to be mixed are pressed together through orifices or interstitial spaces, e.g. between beads
    • B01F25/452—Mixers in which the materials to be mixed are pressed together through orifices or interstitial spaces, e.g. between beads characterised by elements provided with orifices or interstitial spaces
    • B01F25/4523—Mixers in which the materials to be mixed are pressed together through orifices or interstitial spaces, e.g. between beads characterised by elements provided with orifices or interstitial spaces the components being pressed through sieves, screens or meshes which obstruct the whole diameter of the tube
    • B01F25/45231—Mixers in which the materials to be mixed are pressed together through orifices or interstitial spaces, e.g. between beads characterised by elements provided with orifices or interstitial spaces the components being pressed through sieves, screens or meshes which obstruct the whole diameter of the tube the sieves, screens or meshes being cylinders or cones which obstruct the whole diameter of the tube, the flow changing from axial in radial and again in axial
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01M—TESTING STATIC OR DYNAMIC BALANCE OF MACHINES OR STRUCTURES; TESTING OF STRUCTURES OR APPARATUS, NOT OTHERWISE PROVIDED FOR
    • G01M3/00—Investigating fluid-tightness of structures
    • G01M3/02—Investigating fluid-tightness of structures by using fluid or vacuum
    • G01M3/04—Investigating fluid-tightness of structures by using fluid or vacuum by detecting the presence of fluid at the leakage point
    • G01M3/16—Investigating fluid-tightness of structures by using fluid or vacuum by detecting the presence of fluid at the leakage point using electric detection means
    • G01M3/18—Investigating fluid-tightness of structures by using fluid or vacuum by detecting the presence of fluid at the leakage point using electric detection means for pipes, cables or tubes; for pipe joints or seals; for valves; for welds; for containers, e.g. radiators
    • G01M3/186—Investigating fluid-tightness of structures by using fluid or vacuum by detecting the presence of fluid at the leakage point using electric detection means for pipes, cables or tubes; for pipe joints or seals; for valves; for welds; for containers, e.g. radiators for containers, e.g. radiators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/36—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits
    • A61M1/3693—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits using separation based on different densities of components, e.g. centrifuging
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/70—Gravity drainage systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00—General characteristics of the apparatus
    • A61M2205/33—Controlling, regulating or measuring
    • A61M2205/3379—Masses, volumes, levels of fluids in reservoirs, flow rates
    • A61M2205/3386—Low level detectors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00—General characteristics of the apparatus
    • A61M2205/50—General characteristics of the apparatus with microprocessors or computers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
    • A61M5/142—Pressure infusion, e.g. using pumps
    • A61M5/145—Pressure infusion, e.g. using pumps using pressurised reservoirs, e.g. pressurised by means of pistons
    • A61M5/1452—Pressure infusion, e.g. using pumps using pressurised reservoirs, e.g. pressurised by means of pistons pressurised by means of pistons
    • A61M5/1456—Pressure infusion, e.g. using pumps using pressurised reservoirs, e.g. pressurised by means of pistons pressurised by means of pistons with a replaceable reservoir comprising a piston rod to be moved into the reservoir, e.g. the piston rod is part of the removable reservoir

Landscapes

  • Health & Medical Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Vascular Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Anesthesiology (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Emergency Medicine (AREA)
  • Cardiology (AREA)
  • Chemical & Material Sciences (AREA)
  • Dispersion Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Physics & Mathematics (AREA)
  • General Physics & Mathematics (AREA)
  • External Artificial Organs (AREA)

Abstract

A találmány tárgya eljárás és elrendezés vér őnline extracőrpőralisterápiás kezelésére, eljárás és fecskendős szivattyú előremeghatárőzőtt kőncentrációjú őldat főrmájú gyógyhatású készítmény őn-line bejűttatására páciens véráramába és eljárás lamináris áramlásbantartőtt első és másődik főlyadék összekeverésére. A terápiáskezelésnél, amikőr is vért vérfőrrásból felvesznek, az a lényeg, hőgya felvett vért őldat főrmájú gyógyhatású készítménnyel keverik, akeveréket reakciókamrába (85) vezetik és őtt sűgárzás hatásának teszikki, majd őnnan azt elvezetik és visszavezető befőgadó tartálybajűttatják. A reakciókamra (85) centrifűga főrgásban tartőtt eleme,amelyhez besűgárzó lámpa tartőzik. A besűgárzás menetében a vértérfőgatában bekövetkező váltőzásőkat, valamint a besűgárzásfeltételeit követik, ennek alapján a visszamaradó besűgárzási időtmeghatárőzzák, aminek sőrán a kűműlatív fényenergia értékét figyelembeveszik és azt egy előre meghatárőzőtt állandóval összehasőnlítvameghatárőzzák a besűgárzás időtartamának lejártát. A gyógyhatásúkészítmény bejűttatási eljárásának lényege, hőgy a páciens (10)véráramából elvezetett részt flexibilis nyőmástartályba (35)jűttatják, ebből első szállítási ütem mellett vértővábbító vőnalbavezetik, a vér szintjét mérik, az első szállítási ütemet a mért szintalapján állapítják meg, a vértővábbító vőnalba az első szállításiütemnek megfelelő másődik szállítási ütem mellett őldat főrmájúgyógyhatású készítményt jűttatnak és a keveréket a páciens (10)szervezetébe visszavezetik. A fecskendős szivattyú lényege, hőgyfecskendő törzsét mereven megfőgó szerelő tömböt, azőn eltőlhatóanmegvezetett, a fecskendő dűgattyújáhőz kapcsőlódó és a dűgattyútbefőgadó nyílással ellátőtt tőló tömböt, valamint a tőló tömböt aszerelő tömb felületén vezérlő jel hatására eltőló meghajtó egységettartalmaz. A terápiás kezelésre szőlgáló elrendezésnek, amely páciens(10) vérének kezelésére szőlgáló, elszívó járattal közlekedőreakciókamrával (85) van ellátva és a reakciókamráhőz (85)vérveszteséget érzékelő rendszer van csatlakőztatva, az a lényege,hőgy ez a rendszer első végével az elszívó járathőz csatlakőztatőttelső és másődik elektrőmősan vezető csővel, az első elektrőmősanvezető cső másik végét befőgadó első, valamint a másődik elektrőmősanvezető cső első végét befőgadó másődik üreges csatőrnát tartalmazó,belsejében üreges főlyadékátvezetést tartalmazó szigetelő tömbbel,valamint az első és a másődik elektrőmősan vezető csövet az üregesfőlyadékátvezetésen át kapcsőló, főlyadék jelenlétét érzékelőegységgel van ellátva. Ez az elrendezés levegőérzékelővel (25, 30) isellátható, amelynek lényege, hőgy tővábbító vőnal egymással szemköztiőldalán elhelyezett jeladó egységre vezetett első és jelfőgadóegységre vezetett másődik őszcillátőrral, valamint a jThe subject of the invention is a method and arrangement for the on-line extractive therapy treatment of blood, a method and a syringe pump for the on-line introduction of a medicinal product with a predetermined stone concentration into the patient's bloodstream, and a method for mixing laminar flow-maintained primary and secondary slurry. In the case of therapeutic treatment, where blood is taken from a blood boil, the main thing is that the heated blood is mixed with a medicinal preparation in the form of a boiled solution, the mixture is led into a reaction chamber (85) and exposed to radiation, and then it is led away from it and put into a recirculation holding tank. The reaction chamber (85) is an element of the centrifuge kept in motion, to which an illumination lamp is attached. During the course of irradiation, the variables that occur in the blood space and the conditions of irradiation are followed, based on this, the remaining irradiation time is determined, after which the value of the relative light energy is taken into account and, by comparing it with a predetermined constant, the end of the irradiation period is determined. The essence of the delivery procedure of the medicinal product is that the part taken from the patient's bloodstream (10) is delivered to a flexible pressure vessel (35), from which it is introduced into the blood circulation vein in addition to the first delivery rate, the blood level is measured, the first delivery rate is determined on the basis of the measured level, the first delivery rate is placed into the blood circulation vein with a variable delivery rate corresponding to the delivery rate, a dissolved drug with a medicinal effect is delivered and the mixture is returned to the patient's (10) body. The essence of the syringe pump is that it contains a mounting block that rigidly holds the body of the thermosyringe, then a releasably guided, releasable releasable releasable releasable block fitted to the plunger of the syringe and provided with an opening for the resealing of the reciprocating piston, as well as a drive unit that fires the releasable block in response to a control signal on the surface of the block mounting the releasable block. The essence of the arrangement for therapeutic treatment, which is provided with a reaction chamber (85) for treating the patient's (10) blood, with a suction passage, and a blood loss detection system is connected to the reaction chamber heater (85), is that this system is connected to the first end of the suction passage heater and climbs with an electrically conducting pipe, the first sealing the other end of the first electrically conducting pipe, and the first end of the climbing electrically conducting pipe sealing the first end of the climbing electrically conducting pipe with an insulating block containing a hollow buckle and containing a hollow main lead-through inside, as well as the presence of the main lead gripping the first and the climbing electrically-conducting tube through the hollow lead lead-through equipped with a sensor unit. This arrangement can also be seen with an air sensor (25, 30), the essence of which is a primary oscillator led to a transmitter unit located on opposite sides of each other with a heat transmission line and a primary oscillator led to the main signal transmitter unit, as well as the

HU9800776A 1995-01-17 1996-01-16 Method and apparatus for on-line treatment of blood in extracorporeal therapy, method and syringe pump for on-line delivering a predetermined concentration of a medicinal solution into a patient's blood and method for mixing first and second fluids mov... HUP9800776A2 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US37370395A 1995-01-17 1995-01-17

Publications (1)

Publication Number Publication Date
HUP9800776A2 true HUP9800776A2 (en) 1998-07-28

Family

ID=23473514

Family Applications (1)

Application Number Title Priority Date Filing Date
HU9800776A HUP9800776A2 (en) 1995-01-17 1996-01-16 Method and apparatus for on-line treatment of blood in extracorporeal therapy, method and syringe pump for on-line delivering a predetermined concentration of a medicinal solution into a patient's blood and method for mixing first and second fluids mov...

Country Status (12)

Country Link
EP (1) EP0814854A1 (en)
AR (1) AR000901A1 (en)
AU (1) AU4698996A (en)
CA (1) CA2210477C (en)
CO (1) CO4700313A1 (en)
CZ (3) CZ9900757A3 (en)
HU (1) HUP9800776A2 (en)
IL (1) IL116765A0 (en)
NO (1) NO973292L (en)
SK (1) SK96897A3 (en)
TW (1) TW338722B (en)
WO (1) WO1996022117A2 (en)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ITMI20072397A1 (en) 2007-12-20 2009-06-21 Gambro Lundia Ab MEDICAL EQUIPMENT FOR EXTRA-REPAIR TREATMENT
DE202009000053U1 (en) 2009-01-23 2009-09-03 Jing Xiang Kai Industry Co., Ltd. Foot ring spanner
US9399093B2 (en) 2012-01-27 2016-07-26 Fenwal, Inc. Systems and methods for performing online extracorporeal photopheresis
US9814824B2 (en) 2015-06-01 2017-11-14 Asia Pacific Medical Technology Development Company, Ltd Systems and methods for extracorporeal support
US10434240B2 (en) 2015-08-17 2019-10-08 Fenwal, Inc. Methods and systems for processing and washing a photopheresis mononuclear cell product
US10213542B2 (en) 2015-11-04 2019-02-26 Asia Pacific Medical Technology Development Company, Ltd Systems and methods for flow stagnation control
EP3785748A1 (en) * 2015-11-04 2021-03-03 Asia Pacific Medical Technology Development Company, Ltd Systems and methods for flow stagnation control
US10265460B2 (en) 2015-11-04 2019-04-23 Asia Pacific Medical Technology Development Company, Ltd. Systems and methods for providing zones of selective thermal therapy
JP7402827B2 (en) * 2018-06-11 2023-12-21 エピセントアールエックス，インコーポレイテッド Pharmaceutical injection devices, systems and methods
IL293672A (en) * 2019-12-11 2022-08-01 Epicentrx Inc Medication infusion devices, systems, and methods
IT202000003407A1 (en) * 2020-02-19 2021-08-19 Pelham Crescent S R L MACHINE FOR THE EXTRA-BODY PHOTOPHERESIS OF A BIOLOGICAL FLUID
US20220347368A1 (en) * 2021-04-13 2022-11-03 Fenwal, Inc. Systems and methods for performing extracorporeal photopheresis

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1168263A (en) * 1966-03-04 1969-10-22 James C Ii Hobbs Apparatus for Injecting Radio Opaque Liquid into a Vascular System
US3861652A (en) * 1972-11-15 1975-01-21 Du Pont Mixing device
AU562614B2 (en) * 1981-06-12 1987-06-18 Richard L. Edelson External treatment of blood with uv radiation
FR2601252B1 (en) * 1986-05-14 1990-06-08 Piani Jean MEDICATION INJECTION PUMP.
US5104526A (en) * 1987-01-30 1992-04-14 Baxter International Inc. Centrifugation system having an interface detection system
US5191795A (en) * 1987-05-01 1993-03-09 Abbott Laboratories Ultrasonic detector
US4789853A (en) * 1987-06-15 1988-12-06 Gentiluomo Joseph A Detection device for electrically conductive fluids
US4764166A (en) * 1987-08-17 1988-08-16 Fisher Scientific Company Ultrasonic air-in-line detector
DE3837298C1 (en) * 1988-11-03 1990-03-29 Fresenius Ag, 6380 Bad Homburg, De
US5205153A (en) * 1992-01-23 1993-04-27 Cobe Laboratories, Inc. Method and apparatus for detection of air bubbles in tubing
US5254096A (en) * 1992-09-23 1993-10-19 Becton, Dickinson And Company Syringe pump with graphical display or error conditions

Also Published As

Publication number Publication date
EP0814854A1 (en) 1998-01-07
MX9705405A (en) 1997-10-31
IL116765A0 (en) 1996-05-14
WO1996022117A2 (en) 1996-07-25
CZ9900757A3 (en) 2002-11-13
SK96897A3 (en) 1998-07-08
CA2210477C (en) 2005-03-29
WO1996022117A3 (en) 1996-11-07
CA2210477A1 (en) 1996-07-25
AU4698996A (en) 1996-08-07
NO973292D0 (en) 1997-07-16
AR000901A1 (en) 1997-08-06
NO973292L (en) 1997-08-29
CZ9900756A3 (en) 2002-11-13
TW338722B (en) 1998-08-21
CO4700313A1 (en) 1998-12-29
CZ9900758A3 (en) 2002-11-13

Similar Documents

Publication Publication Date Title
HUP9800776A2 (en) Method and apparatus for on-line treatment of blood in extracorporeal therapy, method and syringe pump for on-line delivering a predetermined concentration of a medicinal solution into a patient's blood and method for mixing first and second fluids mov...
US4953565A (en) Endermic application kits for external medicines
KR100346348B1 (en) Apparatus and method for preventing hypotension in dialysis patients
US4908014A (en) Extracorporal thermo-therapy device and method for curing diseases
JP3181071B2 (en) Blood processing equipment
US5074838A (en) Extracorporal thermo-therapy device and method for curing diseases using penetrants
ES2085602T3 (en) ARTIFICIAL KIDNEY.
US4787883A (en) Extracorporal thermo-therapy device and method for curing diseases
CA2188573A1 (en) Cardioplegia delivery apparatus and method of use
US10888495B2 (en) Scraping plate
GB1327334A (en) Container for permitting temperature control of a liquid therein
WO1998039058A1 (en) EXTRACORPOREAL WHOLE BODY HYPERTHERMIA USING ALPHA-STAT REGULATION OF BLOOD pH AND pC0¿2?
JPS62502951A (en) Apparatus and method for rapid injection of circulation maintenance fluid
EP2213317B1 (en) Ozone-therapy blood treatment
RU2252788C1 (en) Device for carrying out membrane-type plasmapheresis in single-needle mode
CN2538343Y (en) Microware heat perfusion circulation therapeutic apparatus
AU2883384A (en) Extracorporeal biospecific polymer treatment of blood iro plasma
JPS60207670A (en) Apparatus for introducing liquid into abdominal cavity
US20160008525A1 (en) Hyperoxygenation/Hyperthermia Treatment Apparatus
CN1411382A (en) Device and method for covering film on internal cavity of conduit
EP3914312A1 (en) System and methods for extracorporeal hyperthermia perfusion (ehp) therapy
RU2014106389A (en) METHOD AND DEVICE OF ORGANISM DETOXICATION
SU1250311A1 (en) Method of treatment of wound infection
CN2314795Y (en) Automatic thermostat therapeutic instrument for nasopharynx
RU2110296C1 (en) Device for exposing biological liquids to radiation