HUP1500023A2 - A method for the preparation of fingolimod - Google Patents
A method for the preparation of fingolimodInfo
- Publication number
- HUP1500023A2 HUP1500023A2 HU1500023A HUP1500023A HUP1500023A2 HU P1500023 A2 HUP1500023 A2 HU P1500023A2 HU 1500023 A HU1500023 A HU 1500023A HU P1500023 A HUP1500023 A HU P1500023A HU P1500023 A2 HUP1500023 A2 HU P1500023A2
- Authority
- HU
- Hungary
- Prior art keywords
- fingolimod
- preparation
- Prior art date
Links
- KKGQTZUTZRNORY-UHFFFAOYSA-N fingolimod Chemical compound CCCCCCCCC1=CC=C(CCC(N)(CO)CO)C=C1 KKGQTZUTZRNORY-UHFFFAOYSA-N 0.000 title 1
- 229960000556 fingolimod Drugs 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D319/00—Heterocyclic compounds containing six-membered rings having two oxygen atoms as the only ring hetero atoms
- C07D319/04—1,3-Dioxanes; Hydrogenated 1,3-dioxanes
- C07D319/06—1,3-Dioxanes; Hydrogenated 1,3-dioxanes not condensed with other rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C213/00—Preparation of compounds containing amino and hydroxy, amino and etherified hydroxy or amino and esterified hydroxy groups bound to the same carbon skeleton
- C07C213/08—Preparation of compounds containing amino and hydroxy, amino and etherified hydroxy or amino and esterified hydroxy groups bound to the same carbon skeleton by reactions not involving the formation of amino groups, hydroxy groups or etherified or esterified hydroxy groups
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CZPV2012-406 | 2012-06-15 | ||
CZ2012-406A CZ2012406A3 (cs) | 2012-06-15 | 2012-06-15 | Způsob výroby fingolimodu založený na otevírání aziridinového kruhu |
PCT/CZ2013/000075 WO2013185740A1 (en) | 2012-06-15 | 2013-06-12 | A method for the preparation of fingolimod |
Publications (2)
Publication Number | Publication Date |
---|---|
HUP1500023A2 true HUP1500023A2 (en) | 2015-04-28 |
HU230655B1 HU230655B1 (hu) | 2017-06-28 |
Family
ID=48740780
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
HU1500023A HU230655B1 (hu) | 2012-06-15 | 2013-06-12 | Eljárás fingolimod előállítására |
Country Status (3)
Country | Link |
---|---|
CZ (1) | CZ2012406A3 (hu) |
HU (1) | HU230655B1 (hu) |
WO (1) | WO2013185740A1 (hu) |
Families Citing this family (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US11696904B2 (en) * | 2020-01-10 | 2023-07-11 | The Regents Of The University Of California | Prodrug for therapeutic applications |
Family Cites Families (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
ATE172711T1 (de) * | 1992-10-21 | 1998-11-15 | Yoshitomi Pharmaceutical | 2-amino-1, 3- propandiolverbindung und immunosuppressium |
JP4079505B2 (ja) | 1998-04-28 | 2008-04-23 | 田辺三菱製薬株式会社 | 2−アミノ−2−[2−(4−オクチルフェニル)エチル]プロパン−1,3−ジオールの新規な製造法 |
CN100548968C (zh) | 2006-03-01 | 2009-10-14 | 徐州师范大学 | 一种制备2-对辛基苯乙基-2-氨基丙二醇盐酸盐的方法 |
CA2717934C (en) | 2008-03-19 | 2017-07-18 | Novartis Ag | Process for the preparation of 2-amino-2- [2-(4-c3-c21-alkyl-phenyl)ethyl] propane-1,3-diols |
JP2014503478A (ja) * | 2010-10-28 | 2014-02-13 | マピ ファーマ リミテッド | フィンゴリモドの調製のための中間の化合物およびプロセス |
CN102120720B (zh) * | 2011-01-25 | 2013-05-22 | 上海华升生物科技有限公司 | 盐酸芬戈莫德的合成新方法 |
-
2012
- 2012-06-15 CZ CZ2012-406A patent/CZ2012406A3/cs not_active IP Right Cessation
-
2013
- 2013-06-12 HU HU1500023A patent/HU230655B1/hu not_active IP Right Cessation
- 2013-06-12 WO PCT/CZ2013/000075 patent/WO2013185740A1/en active Application Filing
Also Published As
Publication number | Publication date |
---|---|
WO2013185740A1 (en) | 2013-12-19 |
CZ2012406A3 (cs) | 2013-12-27 |
HU230655B1 (hu) | 2017-06-28 |
CZ304188B6 (cs) | 2013-12-18 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
MM4A | Lapse of definitive patent protection due to non-payment of fees |