HUP0500259A2 - Új N-(transz-4-izopropil-ciklohexil-karbonil)-D-fenil-alanin forma, eljárás előállítására és alkalmazása - Google Patents

Új N-(transz-4-izopropil-ciklohexil-karbonil)-D-fenil-alanin forma, eljárás előállítására és alkalmazása

Info

Publication number
HUP0500259A2
HUP0500259A2 HU0500259A HUP0500259A HUP0500259A2 HU P0500259 A2 HUP0500259 A2 HU P0500259A2 HU 0500259 A HU0500259 A HU 0500259A HU P0500259 A HUP0500259 A HU P0500259A HU P0500259 A2 HUP0500259 A2 HU P0500259A2
Authority
HU
Hungary
Prior art keywords
trans
isopropylcyclohexylcarbonyl
phenylalanine
process according
methyl ester
Prior art date
Application number
HU0500259A
Other languages
English (en)
Hungarian (hu)
Inventor
Shanmughasamy Rajamahendra
Chandrashekar Aswathanarayanappa
Tom Thomas Puthiaprampil
Madhavan Sridharan
Sambasivam Ganesh
Original Assignee
Biocon Limited
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Biocon Limited filed Critical Biocon Limited
Publication of HUP0500259A2 publication Critical patent/HUP0500259A2/hu

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C233/00—Carboxylic acid amides
    • C07C233/57—Carboxylic acid amides having carbon atoms of carboxamide groups bound to carbon atoms of rings other than six-membered aromatic rings
    • C07C233/63—Carboxylic acid amides having carbon atoms of carboxamide groups bound to carbon atoms of rings other than six-membered aromatic rings having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by carboxyl groups
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
    • A61K31/197—Carboxylic acids, e.g. valproic acid having an amino group the amino and the carboxyl groups being attached to the same acyclic carbon chain, e.g. gamma-aminobutyric acid [GABA], beta-alanine, epsilon-aminocaproic acid or pantothenic acid
    • A61K31/198—Alpha-amino acids, e.g. alanine or edetic acid [EDTA]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00—Systems containing only non-condensed rings
    • C07C2601/12—Systems containing only non-condensed rings with a six-membered ring
    • C07C2601/14—The ring being saturated

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Diabetes (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Endocrinology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Emergency Medicine (AREA)
  • Epidemiology (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
HU0500259A 2002-04-29 2002-04-29 Új N-(transz-4-izopropil-ciklohexil-karbonil)-D-fenil-alanin forma, eljárás előállítására és alkalmazása HUP0500259A2 (hu)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/IN2002/000114 WO2003093222A1 (en) 2002-04-29 2002-04-29 Novel form of n-(trans-4-isopropylcyclohexylcarbonyl)-d-phenylalanine

Publications (1)

Publication Number Publication Date
HUP0500259A2 true HUP0500259A2 (hu) 2005-06-28

Family

ID=29287383

Family Applications (1)

Application Number Title Priority Date Filing Date
HU0500259A HUP0500259A2 (hu) 2002-04-29 2002-04-29 Új N-(transz-4-izopropil-ciklohexil-karbonil)-D-fenil-alanin forma, eljárás előállítására és alkalmazása

Country Status (13)

Country Link
US (1) US7314955B2 (cg-RX-API-DMAC10.html)
EP (1) EP1499586A4 (cg-RX-API-DMAC10.html)
JP (1) JP4137053B2 (cg-RX-API-DMAC10.html)
KR (1) KR20040111490A (cg-RX-API-DMAC10.html)
AU (1) AU2002304281A1 (cg-RX-API-DMAC10.html)
CA (1) CA2481322A1 (cg-RX-API-DMAC10.html)
CZ (1) CZ2004997A3 (cg-RX-API-DMAC10.html)
HR (1) HRP20040920A2 (cg-RX-API-DMAC10.html)
HU (1) HUP0500259A2 (cg-RX-API-DMAC10.html)
IL (1) IL164327A0 (cg-RX-API-DMAC10.html)
MX (1) MXNL04000084A (cg-RX-API-DMAC10.html)
SK (1) SK287644B6 (cg-RX-API-DMAC10.html)
WO (1) WO2003093222A1 (cg-RX-API-DMAC10.html)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2003093222A1 (en) 2002-04-29 2003-11-13 Biocon Limited Novel form of n-(trans-4-isopropylcyclohexylcarbonyl)-d-phenylalanine
US6861553B2 (en) 2002-07-03 2005-03-01 Teva Pharmaceuticals Industries Ltd. Process for preparing nateglinide and intermediates thereof
US7358390B2 (en) 2002-07-18 2008-04-15 Teva Pharmaceutical Industries Ltd. Polymorphic forms of nateglinide
US7420084B2 (en) * 2002-07-18 2008-09-02 Teva Pharmaceutical Industries Ltd. Polymorphic forms of nateglinide
US7148376B2 (en) 2002-07-18 2006-12-12 Teva Pharmaceutical Industries Ltd. Polymorphic forms of nateglinide
US7534913B2 (en) 2002-07-18 2009-05-19 Teva Pharmaceutica Industries Ltd. Crystalline form of nateglinide
WO2004020396A1 (en) * 2002-08-28 2004-03-11 Dr. Reddy's Laboratories Limited Crystalline form of nateglinide and process for preparation thereof
US7449519B2 (en) * 2003-02-18 2008-11-11 Konishi Co., Ltd. Curing resin, method for producing same and curing resin composition
HU227073B1 (hu) * 2003-07-10 2010-06-28 Richter Gedeon Nyrt Eljárás királisan tiszta N-(transz-4-izopropil-ciklohexilkarbonil)-D-fenil-alanin (nateglinid) és kristálymódosulatainak elõállítására, valamint a G-kristálymódosulata
WO2005110395A1 (en) * 2004-05-19 2005-11-24 University Of South Carolina System and device for magnetic drug targeting with magnetic drug carrier particles
GB0413084D0 (en) * 2004-06-11 2004-07-14 Cipla Ltd Process
US20100004334A1 (en) * 2008-07-01 2010-01-07 Mead Johnson Nutrition Company Nutritional Compositions Containing Punicalagins
US11390830B2 (en) 2018-10-05 2022-07-19 The Chemours Company Fc, Llc Compositions comprising 1,2-dichloro-1,2-difluoroethylene for use in cleaning and solvent applications

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS6354321A (ja) * 1985-03-27 1988-03-08 Ajinomoto Co Inc 血糖降下剤
US4814684A (en) * 1987-09-30 1989-03-21 Trw Inc. Apparatus for extending the Vout/Vin ratio of a DC-to-DC converter
US5463116A (en) 1991-07-30 1995-10-31 Ajinomoto Co., Inc. Crystals of N- (trans-4-isopropylcyclohexlycarbonyl)-D-phenylalanine and methods for preparing them
DE69217762T2 (de) 1991-07-30 1997-10-09 Ajinomoto Kk Kristalle von N-(Trans-4-isopropylcyclohexylcarbonyl)-D-phenylalanin und Verfahren zu ihrer Herstellung
WO2003093222A1 (en) 2002-04-29 2003-11-13 Biocon Limited Novel form of n-(trans-4-isopropylcyclohexylcarbonyl)-d-phenylalanine

Also Published As

Publication number Publication date
KR20040111490A (ko) 2004-12-31
SK50052004A3 (sk) 2005-03-04
US7314955B2 (en) 2008-01-01
SK287644B6 (sk) 2011-05-06
MXNL04000084A (es) 2006-02-28
EP1499586A1 (en) 2005-01-26
JP2005523933A (ja) 2005-08-11
IL164327A0 (en) 2005-12-18
CZ2004997A3 (cs) 2005-01-12
WO2003093222A1 (en) 2003-11-13
CA2481322A1 (en) 2003-11-13
US20050165108A1 (en) 2005-07-28
AU2002304281A1 (en) 2003-11-17
HRP20040920A2 (en) 2005-02-28
EP1499586A4 (en) 2006-01-18
JP4137053B2 (ja) 2008-08-20

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Legal Events

Date Code Title Description
FD9A Lapse of provisional protection due to non-payment of fees