HUP0204150A2 - A cisz-lítium-4-ciano-4-[3-(ciklopentil-oxi)-4-metoxi-fenil]-ciklohexánkarboxilát monohidrátja, eljárás az előállítására és ezt tartalmazó gyógyszerkészítmény - Google Patents

A cisz-lítium-4-ciano-4-[3-(ciklopentil-oxi)-4-metoxi-fenil]-ciklohexánkarboxilát monohidrátja, eljárás az előállítására és ezt tartalmazó gyógyszerkészítmény

Info

Publication number
HUP0204150A2
HUP0204150A2 HU0204150A HUP0204150A HUP0204150A2 HU P0204150 A2 HUP0204150 A2 HU P0204150A2 HU 0204150 A HU0204150 A HU 0204150A HU P0204150 A HUP0204150 A HU P0204150A HU P0204150 A2 HUP0204150 A2 HU P0204150A2
Authority
HU
Hungary
Prior art keywords
cyclohexanecarboxylate
cyclopentyloxy
monohydrate
methoxyphenyl
cyano
Prior art date
Application number
HU0204150A
Other languages
English (en)
Inventor
Kevin Scott Webb
Original Assignee
Smithkline Beecham Corp.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Smithkline Beecham Corp. filed Critical Smithkline Beecham Corp.
Publication of HUP0204150A2 publication Critical patent/HUP0204150A2/hu
Publication of HUP0204150A3 publication Critical patent/HUP0204150A3/hu

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C255/00—Carboxylic acid nitriles
    • C07C255/45—Carboxylic acid nitriles having cyano groups bound to carbon atoms of rings other than six-membered aromatic rings
    • C07C255/46—Carboxylic acid nitriles having cyano groups bound to carbon atoms of rings other than six-membered aromatic rings to carbon atoms of non-condensed rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C255/00—Carboxylic acid nitriles
    • C07C255/49—Carboxylic acid nitriles having cyano groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton
    • C07C255/50—Carboxylic acid nitriles having cyano groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton to carbon atoms of non-condensed six-membered aromatic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00—Systems containing only non-condensed rings
    • C07C2601/06—Systems containing only non-condensed rings with a five-membered ring
    • C07C2601/08—Systems containing only non-condensed rings with a five-membered ring the ring being saturated
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00—Systems containing only non-condensed rings
    • C07C2601/12—Systems containing only non-condensed rings with a six-membered ring
    • C07C2601/14—The ring being saturated

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Neurology (AREA)
  • Pulmonology (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Rheumatology (AREA)
  • Pain & Pain Management (AREA)
  • Psychiatry (AREA)
  • Immunology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Hospice & Palliative Care (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

A találmány az (I) képletű cisz-lítium-4-ciano-4-[3-(ciklopentil-oxi)-4-metoxi-fenil]-ciklohexán-karboxilát monohidrátra, a vegyületelőállítási eljárására, valamint a vegyületet hatóanyagként tartalmazógyógyszerkészítményekre vonatkozik. Ó
HU0204150A 2000-01-26 2001-01-18 Monohydrate of cis-lithium-cyano-4-[3-(cyclopentyloxy)-4-methoxyphenyl]cyclohexanecarboxylate, process for its preparation and pharmaceutical compositions containing the same HUP0204150A3 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US17812900P 2000-01-26 2000-01-26
PCT/US2001/001487 WO2001055094A1 (en) 2000-01-26 2001-01-18 Monohydrate of cis-lithium-cyano-4-[3-(cyclopentyloxy)-4-methoxyphenyl]cyclohexanecarboxylate

Publications (2)

Publication Number Publication Date
HUP0204150A2 true HUP0204150A2 (hu) 2003-04-28
HUP0204150A3 HUP0204150A3 (en) 2003-05-28

Family

ID=22651319

Family Applications (1)

Application Number Title Priority Date Filing Date
HU0204150A HUP0204150A3 (en) 2000-01-26 2001-01-18 Monohydrate of cis-lithium-cyano-4-[3-(cyclopentyloxy)-4-methoxyphenyl]cyclohexanecarboxylate, process for its preparation and pharmaceutical compositions containing the same

Country Status (36)

Country Link
US (1) US6699903B2 (hu)
EP (1) EP1250313B1 (hu)
JP (1) JP2003520842A (hu)
KR (1) KR20020073183A (hu)
CN (1) CN1157371C (hu)
AP (1) AP1432A (hu)
AR (1) AR027273A1 (hu)
AT (1) ATE344235T1 (hu)
AU (1) AU3282201A (hu)
BG (1) BG106959A (hu)
BR (1) BR0107709A (hu)
CA (1) CA2397758A1 (hu)
CO (1) CO5300517A1 (hu)
CY (1) CY1108515T1 (hu)
CZ (1) CZ20022590A3 (hu)
DE (1) DE60124221T2 (hu)
DK (1) DK1250313T3 (hu)
DZ (1) DZ3285A1 (hu)
EA (1) EA200200791A1 (hu)
EG (1) EG24065A (hu)
ES (1) ES2273804T3 (hu)
HK (1) HK1051030A1 (hu)
HU (1) HUP0204150A3 (hu)
IL (1) IL150400A0 (hu)
MA (1) MA25652A1 (hu)
MX (1) MXPA02007300A (hu)
MY (1) MY122802A (hu)
NO (1) NO20023378L (hu)
NZ (1) NZ519799A (hu)
OA (1) OA12159A (hu)
PE (1) PE20011040A1 (hu)
PL (1) PL356832A1 (hu)
PT (1) PT1250313E (hu)
SK (1) SK10942002A3 (hu)
WO (1) WO2001055094A1 (hu)
ZA (1) ZA200205925B (hu)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0011802D0 (en) * 2000-05-16 2000-07-05 Smithkline Beecham Method for enhancing cognitive function

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0633776B1 (en) * 1992-04-02 2001-05-09 Smithkline Beecham Corporation Compounds useful for treating allergic and inflammatory diseases
UA67753C2 (uk) * 1997-10-10 2004-07-15 Смітклайн Бічам Корпорейшн Спосіб отримання заміщених 4-феніл-4-ціанциклогексанових кислот

Also Published As

Publication number Publication date
AP1432A (en) 2005-06-20
SK10942002A3 (sk) 2002-11-06
CN1157371C (zh) 2004-07-14
EP1250313B1 (en) 2006-11-02
ZA200205925B (en) 2003-11-21
CA2397758A1 (en) 2001-08-02
EP1250313A1 (en) 2002-10-23
DK1250313T3 (da) 2007-02-12
MA25652A1 (fr) 2002-12-31
WO2001055094A1 (en) 2001-08-02
AR027273A1 (es) 2003-03-19
EP1250313A4 (en) 2005-09-21
US6699903B2 (en) 2004-03-02
DE60124221D1 (de) 2006-12-14
AU3282201A (en) 2001-08-07
HUP0204150A3 (en) 2003-05-28
DZ3285A1 (fr) 2001-08-02
MY122802A (en) 2006-05-31
BR0107709A (pt) 2002-11-19
NO20023378D0 (no) 2002-07-12
NO20023378L (no) 2002-07-12
EA200200791A1 (ru) 2002-12-26
KR20020073183A (ko) 2002-09-19
DE60124221T2 (de) 2007-09-13
JP2003520842A (ja) 2003-07-08
NZ519799A (en) 2004-04-30
ES2273804T3 (es) 2007-05-16
PE20011040A1 (es) 2001-10-31
CN1395556A (zh) 2003-02-05
CZ20022590A3 (cs) 2003-01-15
CO5300517A1 (es) 2003-07-31
PT1250313E (pt) 2007-01-31
HK1051030A1 (zh) 2003-07-18
US20030032670A1 (en) 2003-02-13
PL356832A1 (en) 2004-07-12
ATE344235T1 (de) 2006-11-15
BG106959A (en) 2003-05-30
EG24065A (en) 2008-05-08
AP2002002566A0 (en) 2002-06-30
OA12159A (en) 2006-05-08
CY1108515T1 (el) 2014-04-09
IL150400A0 (en) 2002-12-01
MXPA02007300A (es) 2002-11-29

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Legal Events

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