HUP0203908A2 - Ozmotikus adagolórendszer és eljárás elsősorban gyógyszer adagolására - Google Patents

Ozmotikus adagolórendszer és eljárás elsősorban gyógyszer adagolására

Info

Publication number
HUP0203908A2
HUP0203908A2 HU0203908A HUP0203908A HUP0203908A2 HU P0203908 A2 HUP0203908 A2 HU P0203908A2 HU 0203908 A HU0203908 A HU 0203908A HU P0203908 A HUP0203908 A HU P0203908A HU P0203908 A2 HUP0203908 A2 HU P0203908A2
Authority
HU
Hungary
Prior art keywords
implant
catheter
receiving unit
osmotic
medicine
Prior art date
Application number
HU0203908A
Other languages
English (en)
Inventor
Stephen A. Berry
Craig R. Davis
Pamela Ferreira
Juan M. Harrison
Li-Ming Lau
Judy A. Magruder
Paul R. Magruder
Wouter Roorda
Gregory R. Stewart
Original Assignee
Alza Corporation
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Alza Corporation filed Critical Alza Corporation
Publication of HUP0203908A2 publication Critical patent/HUP0203908A2/hu
Publication of HUP0203908A3 publication Critical patent/HUP0203908A3/hu

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M39/00—Tubes, tube connectors, tube couplings, valves, access sites or the like, specially adapted for medical use
    • A61M39/02—Access sites
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A61K9/0024—Solid, semi-solid or solidifying implants, which are implanted or injected in body tissue
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0002—Galenical forms characterised by the drug release technique; Application systems commanded by energy
    • A61K9/0004—Osmotic delivery systems; Sustained release driven by osmosis, thermal energy or gas
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin

Landscapes

  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Biomedical Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Neurosurgery (AREA)
  • Dermatology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hematology (AREA)
  • Anesthesiology (AREA)
  • Pulmonology (AREA)
  • Materials For Medical Uses (AREA)
  • Separation Using Semi-Permeable Membranes (AREA)
  • Medicinal Preparation (AREA)
  • External Artificial Organs (AREA)
  • Media Introduction/Drainage Providing Device (AREA)
  • Infusion, Injection, And Reservoir Apparatuses (AREA)
  • Prostheses (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)

Abstract

Az adagolórendszer implantátumot (10) tartalmaz, amelyben nedvességhatására duzzadó ozmotikus anyag van elhelyezve, és a gyógyszer vagymás hatóanyag számára kamra van kialakítva. Az implantátum (10) egyikvége (16) féligáteresztő membránnal van lezárva, és a másik végén (18)a gyógyszert vagy más hatóanyagot kivezető adagolónyílás vankialakítva. A rendszer az implantátum (10) másik végének (18)befogadására alkalmas, páciensbe beültethető fogadóegységet (12) istartalmaz, amelyhez egy katéter (14) van kapcsolva. A katéter (14)bemenete a fogadóegységbe (12) behelyezett implantátum (10)adagolónyílásához csatlakozik. A beültetett fogadóegység (12)összeköttetést biztosít a katéter (14) és az implantátum (10) között,és lehetővé teszi az implantátum (10) periodikus cseréjét a katéter(14) és a fogadóegység (12) bennhagyása mellett. Az eljárás során egykatéterrel ellátott fogadóegységet ültetnek be egy páciens testébe, ésa katéter szabad végét a páciens testében egy kezelési területrevezetik be; a fogadóegységhez egy ozmotikus implantátumotcsatlakoztatunk, amelyből gyógyszert vagy más hatóanyagot adagolnak akatéter belsejébe; szelektíven folyadékot engednek az ozmotikusimplantátumba; és a gyógyszert vagy más hatóanyagot az ozmotikusimplantátumból a katéteren át a kezelési helyre továbbítják. Ó
HU0203908A 1999-12-27 2000-12-13 Osmotic delivery system and method for delivery first of all of medicine HUP0203908A3 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US17164799P 1999-12-27 1999-12-27
PCT/US2000/034315 WO2001047595A1 (en) 1999-12-27 2000-12-13 Osmotic beneficial agent delivery system

Publications (2)

Publication Number Publication Date
HUP0203908A2 true HUP0203908A2 (hu) 2003-03-28
HUP0203908A3 HUP0203908A3 (en) 2005-01-28

Family

ID=22624590

Family Applications (1)

Application Number Title Priority Date Filing Date
HU0203908A HUP0203908A3 (en) 1999-12-27 2000-12-13 Osmotic delivery system and method for delivery first of all of medicine

Country Status (20)

Country Link
US (2) US20020032401A1 (hu)
EP (1) EP1246662B1 (hu)
JP (1) JP2003518421A (hu)
KR (1) KR100743403B1 (hu)
CN (1) CN1230224C (hu)
AT (1) ATE303174T1 (hu)
AU (1) AU782252B2 (hu)
CA (1) CA2395362A1 (hu)
DE (1) DE60022394T2 (hu)
DK (1) DK1246662T3 (hu)
ES (1) ES2246914T3 (hu)
HU (1) HUP0203908A3 (hu)
IL (1) IL150489A0 (hu)
MX (1) MXPA02006458A (hu)
NO (1) NO20023088L (hu)
NZ (1) NZ519810A (hu)
PL (1) PL356639A1 (hu)
PT (1) PT1246662E (hu)
WO (1) WO2001047595A1 (hu)
ZA (1) ZA200205149B (hu)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP4680939B2 (ja) * 2004-02-10 2011-05-11 シネコー・エルエルシー 治療薬用脈管内送達システム
AU2007201808B8 (en) * 2006-04-26 2013-09-05 Sun Pharmaceutical Advanced Research Company Ltd A method for alleviating signs and symptoms of spasticity
US8401213B2 (en) * 2008-03-31 2013-03-19 Cochlear Limited Snap-lock coupling system for a prosthetic device
KR100986140B1 (ko) * 2008-08-18 2010-10-07 한국전력공사 태양전지 겸용 원자력전지
WO2010138911A1 (en) 2009-05-29 2010-12-02 Otologics, Llc Implantable auditory stimulation system and method with offset implanted microphones
US9056204B2 (en) 2010-10-29 2015-06-16 Cochlear Limited Universal implant
US11071869B2 (en) 2016-02-24 2021-07-27 Cochlear Limited Implantable device having removable portion
CN106037988B (zh) * 2016-07-05 2018-01-05 大连大学 一种针对实验动物局部的多功能喷液给药组合装置
CN109045454B (zh) * 2018-10-25 2021-02-02 北京光捷扬基健康科技有限公司 一种中耳重复给药装置及人工耳蜗植入电极
CN111659020A (zh) * 2020-06-11 2020-09-15 福建医科大学附属第一医院 一种用于脑胶质瘤的诊断装置

Family Cites Families (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4203439A (en) 1976-11-22 1980-05-20 Alza Corporation Osmotic system with volume amplifier for increasing amount of agent delivered therefrom
US4111203A (en) 1976-11-22 1978-09-05 Alza Corporation Osmotic system with means for improving delivery kinetics of system
US4111202A (en) 1976-11-22 1978-09-05 Alza Corporation Osmotic system for the controlled and delivery of agent over time
DE2721752C2 (de) * 1977-05-13 1983-12-29 Siemens AG, 1000 Berlin und 8000 München In einen menschlichen oder tierischen Körper implantierbares Gerät zur Infusion einer medizinischen Flüssigkeit
US4781693A (en) * 1983-09-02 1988-11-01 Minntech Corporation Insulin dispenser for peritoneal cavity
US4927633A (en) * 1984-03-19 1990-05-22 Alza Corporation Dispenser for delivering drug to livestock
JPS61162956A (ja) * 1985-01-11 1986-07-23 東レ株式会社 リ−クバル−ンカテ−テル
US4865845A (en) * 1986-03-21 1989-09-12 Alza Corporation Release rate adjustment of osmotic or diffusional delivery devices
US4886502A (en) * 1986-12-09 1989-12-12 Thermedics, Inc. Peritoneal access catheter
US5129889A (en) * 1987-11-03 1992-07-14 Hahn John L Synthetic absorbable epidural catheter
US5487739A (en) * 1987-11-17 1996-01-30 Brown University Research Foundation Implantable therapy systems and methods
US5057318A (en) * 1988-12-13 1991-10-15 Alza Corporation Delivery system for beneficial agent over a broad range of rates
US5034229A (en) * 1988-12-13 1991-07-23 Alza Corporation Dispenser for increasing feed conversion of hog
US5037420A (en) * 1988-12-13 1991-08-06 Alza Corporation Delivery system comprising two sections for delivering somatotropin
US4976966A (en) * 1988-12-29 1990-12-11 Alza Corporation Delayed release osmotically driven fluid dispenser
US5203770A (en) * 1990-04-20 1993-04-20 Regents Of The University Of Minnesota Method and apparatus for catheterization
US5180591A (en) * 1990-07-11 1993-01-19 Alza Corporation Delivery device with a protective sleeve
US5458570A (en) * 1991-01-22 1995-10-17 May, Jr.; James W. Absorbable catheter and method of using the same
US5861166A (en) * 1991-03-12 1999-01-19 Alza Corporation Delivery device providing beneficial agent stability
US5536243A (en) * 1994-12-13 1996-07-16 Jeyendran; Rajasingam S. Time-release insemination device
US5690952A (en) * 1995-06-07 1997-11-25 Judy A. Magruder et al. Implantable system for delivery of fluid-sensitive agents to animals
PT877599E (pt) * 1996-02-02 2003-08-29 Alza Corp Administracao continua de leuprolido utilizando um sistema implantavel
ZA981610B (en) * 1997-03-24 1999-08-26 Alza Corp Self adjustable exit port.
US6183461B1 (en) * 1998-03-11 2001-02-06 Situs Corporation Method for delivering a medication
US20010041870A1 (en) * 1999-03-09 2001-11-15 Edward M. Gillis Implantable device for access to a treatment site
US6436091B1 (en) * 1999-11-16 2002-08-20 Microsolutions, Inc. Methods and implantable devices and systems for long term delivery of a pharmaceutical agent
US6464688B1 (en) * 2000-02-15 2002-10-15 Microsolutions, Inc. Osmotic pump delivery system with flexible drug compartment

Also Published As

Publication number Publication date
NO20023088L (no) 2002-08-27
WO2001047595A1 (en) 2001-07-05
CA2395362A1 (en) 2001-07-05
ZA200205149B (en) 2003-11-17
EP1246662B1 (en) 2005-08-31
IL150489A0 (en) 2002-12-01
KR20020062994A (ko) 2002-07-31
AU782252B2 (en) 2005-07-14
KR100743403B1 (ko) 2007-07-30
HUP0203908A3 (en) 2005-01-28
DE60022394D1 (de) 2005-10-06
DK1246662T3 (da) 2006-01-16
NO20023088D0 (no) 2002-06-26
CN1230224C (zh) 2005-12-07
ES2246914T3 (es) 2006-03-01
CN1437491A (zh) 2003-08-20
AU2109601A (en) 2001-07-09
PT1246662E (pt) 2005-11-30
US20030083647A1 (en) 2003-05-01
NZ519810A (en) 2004-05-28
US20020032401A1 (en) 2002-03-14
JP2003518421A (ja) 2003-06-10
ATE303174T1 (de) 2005-09-15
PL356639A1 (en) 2004-06-28
DE60022394T2 (de) 2006-06-29
MXPA02006458A (es) 2003-01-28
EP1246662A1 (en) 2002-10-09

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Legal Events

Date Code Title Description
FD9A Lapse of provisional protection due to non-payment of fees