HUP0203049A3 - Enzymatic synthesis of deoxyribonucleosides - Google Patents

Enzymatic synthesis of deoxyribonucleosides

Info

Publication number
HUP0203049A3
HUP0203049A3 HU0203049A HUP0203049A HUP0203049A3 HU P0203049 A3 HUP0203049 A3 HU P0203049A3 HU 0203049 A HU0203049 A HU 0203049A HU P0203049 A HUP0203049 A HU P0203049A HU P0203049 A3 HUP0203049 A3 HU P0203049A3
Authority
HU
Hungary
Prior art keywords
deoxyribonucleosides
enzymatic synthesis
enzymatic
synthesis
Prior art date
Application number
HU0203049A
Other languages
English (en)
Original Assignee
Roche Diagnostics Gmbh
Pasteur Institut
Pharma Waldhof Gmbh & Co Kg
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=8238824&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=HUP0203049(A3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Roche Diagnostics Gmbh, Pasteur Institut, Pharma Waldhof Gmbh & Co Kg filed Critical Roche Diagnostics Gmbh
Publication of HUP0203049A2 publication Critical patent/HUP0203049A2/hu
Publication of HUP0203049A3 publication Critical patent/HUP0203049A3/hu

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P19/00—Preparation of compounds containing saccharide radicals
    • C12P19/26—Preparation of nitrogen-containing carbohydrates
    • C12P19/28—N-glycosides
    • C12P19/38—Nucleosides
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004—Oxidoreductases (1.)
    • C12N9/0006—Oxidoreductases (1.) acting on CH-OH groups as donors (1.1)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10—Transferases (2.)
    • C12N9/1048—Glycosyltransferases (2.4)
    • C12N9/1051—Hexosyltransferases (2.4.1)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10—Transferases (2.)
    • C12N9/1048—Glycosyltransferases (2.4)
    • C12N9/1077—Pentosyltransferases (2.4.2)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10—Transferases (2.)
    • C12N9/12—Transferases (2.) transferring phosphorus containing groups, e.g. kinases (2.7)
    • C12N9/1205—Phosphotransferases with an alcohol group as acceptor (2.7.1), e.g. protein kinases
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/88—Lyases (4.)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/90—Isomerases (5.)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P19/00—Preparation of compounds containing saccharide radicals
    • C12P19/02—Monosaccharides
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P19/00—Preparation of compounds containing saccharide radicals
    • C12P19/24—Preparation of compounds containing saccharide radicals produced by the action of an isomerase, e.g. fructose
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P9/00—Preparation of organic compounds containing a metal or atom other than H, N, C, O, S or halogen

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
HU0203049A 1999-08-20 2000-08-18 Enzymatic synthesis of deoxyribonucleosides HUP0203049A3 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP99116425 1999-08-20
PCT/EP2000/008088 WO2001014566A2 (en) 1999-08-20 2000-08-18 Enzymatic synthesis of deoxyribonucleosides

Publications (2)

Publication Number Publication Date
HUP0203049A2 HUP0203049A2 (hu) 2002-12-28
HUP0203049A3 true HUP0203049A3 (en) 2007-03-28

Family

ID=8238824

Family Applications (1)

Application Number Title Priority Date Filing Date
HU0203049A HUP0203049A3 (en) 1999-08-20 2000-08-18 Enzymatic synthesis of deoxyribonucleosides

Country Status (10)

Country Link
US (2) US7229797B1 (hu)
EP (1) EP1206551B2 (hu)
JP (1) JP2003507071A (hu)
KR (1) KR20020048930A (hu)
AT (1) ATE431416T1 (hu)
AU (1) AU6571700A (hu)
CA (1) CA2382462A1 (hu)
DE (1) DE60042209D1 (hu)
HU (1) HUP0203049A3 (hu)
WO (1) WO2001014566A2 (hu)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6965018B2 (en) 2000-06-06 2005-11-15 Bristol-Myers Squibb Company Antibodies directed to B7-related polypeptide, BSL-2
US20030031675A1 (en) 2000-06-06 2003-02-13 Mikesell Glen E. B7-related nucleic acids and polypeptides useful for immunomodulation
CA2380804A1 (en) * 2001-05-01 2002-11-01 Mitsui Chemicals, Inc. Method for producing cytosine nucleosides compounds
US7381555B2 (en) 2001-09-14 2008-06-03 Institut Pasteur Lactobacillus N-deoxyribosyl transferases, corresponding nucleotide sequences and their uses
FR2829774B1 (fr) * 2001-09-14 2004-09-03 Pasteur Institut N-desoxyribosyltransferases de lactobacilles, sequences nucleotidiques correspondantes et leurs applications
US20040214314A1 (en) 2001-11-02 2004-10-28 Friedrich Srienc High throughput bioreactor
EP1636246B1 (en) * 2003-06-24 2015-08-19 Scientist of Fortune S.A. Production of 2 -deoxynucleosides and 2 -deoxynucleoside precursors from 2-dehydro-3-deoxy-d-gluconate
EP1491549A1 (en) * 2003-06-24 2004-12-29 Evologic S.A. Production of 2'-deoxynucleosides and 2'-deoxynucleoside precursors from 2-dehydro-3-deoxy-D-gluconate
GB2403950A (en) * 2003-07-18 2005-01-19 Mitsui Chemicals Inc Pyrimidine nucleosides from reaction of sugar phosphate with pyrimidine base derivative & enzyme having cytosine nucleoside phosphorylase activity
EP1690946A4 (en) * 2003-11-11 2011-06-15 Mitsui Chemicals Inc PROCESS FOR THE PRODUCTION OF PENTOSE-5-PHOSPHATE ESTER
FR2853906B1 (fr) * 2004-06-07 2006-04-14 Pasteur Institut N-desoxyribosyltransferases de lactobacilles, sequences nucleotidiques correspondantes et leurs applications
LT2660336T (lt) 2008-06-11 2017-10-10 Orion Pharma (Uk) Limited Izoterminė nukleorūgšties amplifkacija
WO2014072487A1 (en) * 2012-11-08 2014-05-15 Centre National De La Recherche Scientifique (Cnrs) New phosphodeoxyribosyltransferase mutant enzymes and uses thereof
WO2014177585A2 (en) * 2013-04-29 2014-11-06 Plasmia Biotech, S.L Biocatalytic production of nucleoside analogues as active pharmaceutical ingredients
JP2015160832A (ja) * 2014-02-27 2015-09-07 大陽日酸株式会社 ヌクレオシド化合物の製造方法
SG11202012111UA (en) 2018-07-09 2021-01-28 Codexis Inc Engineered purine nucleoside phosphorylase variant enzymes
US11034948B2 (en) * 2018-07-09 2021-06-15 Codexis, Inc. Engineered phosphopentomutase variant enzymes
EP3820473A4 (en) 2018-07-09 2022-05-11 Merck Sharp & Dohme Corp. ENZYMATIC SYNTHESIS OF 4'-ETHINYL NUCLEOSIDE ANALOGUES
KR20220034220A (ko) * 2019-08-28 2022-03-17 이너 몽골리아, 에펜 바이오테크 컴퍼니 리미티드 대장균 기반 재조합 균주 및 이의 구축 방법과 응용
CN110592084B (zh) * 2019-08-28 2023-07-28 内蒙古伊品生物科技有限公司 一种rhtA基因启动子改造的重组菌株及其构建方法与应用

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS56166199A (en) 1980-04-23 1981-12-21 Wellcome Found Antiinflammatory compound
JPS5863393A (ja) 1981-10-13 1983-04-15 Ajinomoto Co Inc リボノフラノシル又はデオキシリボフラノシルプリン誘導体の製造法
EP0090417B1 (en) 1982-04-01 1989-03-01 Yamasa Shoyu Kabushiki Kaisha Process for producing 3'-deoxyguanosine
CA2028119C (en) 1989-02-28 2000-05-16 Hiroshi Yamauchi Process for producing nucleosides
CA2064754C (en) * 1989-07-31 1996-06-18 Vladimir Ivanovich Baranov Method of preparing polypeptides in a cell-free translation system
US5728554A (en) * 1995-04-11 1998-03-17 Cytel Corporation Enzymatic synthesis of glycosidic linkages

Also Published As

Publication number Publication date
AU6571700A (en) 2001-03-19
CA2382462A1 (en) 2001-03-01
HUP0203049A2 (hu) 2002-12-28
DE60042209D1 (de) 2009-06-25
WO2001014566A2 (en) 2001-03-01
EP1206551B1 (en) 2009-05-13
EP1206551B2 (en) 2011-10-26
US20080280329A1 (en) 2008-11-13
WO2001014566A3 (en) 2001-09-20
US7229797B1 (en) 2007-06-12
KR20020048930A (ko) 2002-06-24
JP2003507071A (ja) 2003-02-25
EP1206551A2 (en) 2002-05-22
ATE431416T1 (de) 2009-05-15

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Legal Events

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FD9A Lapse of provisional protection due to non-payment of fees